Peanuts Case Study

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Introduction
Peanuts are considered one of the most allergenic foods, as they are one of the eight major allergens that must be listed on the packaging of foods in the United States (FARE)*. Peanuts cause roughly 0.5% to 2% of food allergens worldwide (Cabanos and other 2011)*. These reactions caused by peanuts can be anywhere from a mild skin reaction to deathly anaphylactic shock. Although peanuts cause allergies, they are often used in food processing. They provide important nutrients such as fats and proteins. While there are other foods that can provide similar nutrients (i.e. soybeans, beans, etc.), peanuts are still commonly used.
The proteins found in peanuts are the cause of peanut allergies. There are a total of thirteen different …show more content…

These seeds were germinated for around five to ten days, depending on the conditions applied. The reasoning behind the germination conditions is not fully explained. After germination, all parts of the plant, including the germinated seeds, cotyledons, plumules, hypocotyls and radicles were separated from one another to be tested. The main methods used for this study were ELISA and Western blot analysis.
Proteins from the peanut samples are extracted for comparison from short-term germinated. The protein concentration is determined using Bradford analysis.
The next step is to purify the protein Ara h1 using DEAE Fast Flow and high performance liquid chromatography. The purity of Ara h1 was measured by SDS-PAGE gel stained with Coomassie Brilliant Blue.
Rabbits were used for the testing of antibodies against Ara h1. The purified Ara h1 was injected into rabbits.
The ELISA method was used to examine the immunoreactivity of Ara h1. The results were read in a spectrophotometer at 450 nm. The purified Ara h1 proteins were used to construct a standard curve.
Electrophoresis was used to examine the whole peanut protein extracts.
Western blotting was used to detect Ara h1 or its protein fragments.
All of these methods seemed to be reasonable and the most efficient for what needed to be

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