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Penicillin-The discovery that changed the world, but for how long? Accidents can often turn positive, or in some cases, they can even become revolutionary. The discovery of Penicillin changed the world immensely and it was all due to an accident one day in the lab. Penicillin changed the history of medicine for the better, saving millions of lives since its discovery. Even today, it is used by millions daily, from prescriptions from the pharmacy to life saving drugs in the hospital. However, unless something changes in the near future, history could soon reverse, and the power of penicillin could soon be diminished. Prior to the discovery of penicillin, the only available treatments for bacterial infections were all highly toxic; arsenic, …show more content…
Some of the bacteria that antibiotics treat are actually becoming resistant to the antibiotics meaning they lose all power. Without the power of antibiotics, these infections cannot be treated, which is proving to be a huge issue, as it’s spreading fast. Currently 700,000 have died from antibiotic resistance, which is a lot higher than the statistics for deaths caused by measles, cholera and tetanus combined. This is showing that already, it has already caused a lot of damage, and it continues to spread.(Walsh, 2014) Antibiotic resistance can spread in various ways, stemming from the bottom of the food chain to other human beings. Crops can be sprayed with water or fertiliser which contain drug resistant bacteria. These crops can be eaten by humans, transmitting the resistant bacteria and it can also be spread to crop-eating animals which some humans also consume, also spreading the resistant bacteria. The drug resistant bacteria are then transmitted among humans, from hospital environments to even in the local community, meaning nobody is immune to getting it. (CDC Office of Infectious Diseases (OID), …show more content…
2017. The Discovery of Penicillin—New Insights After More Than 75 Years of Clinical Use. Emerging Infectious Diseases, 23: 849-853. Kardos, N. & Demain. A. L. 2011. Penicillin: the medicine with the greatest impact on therapeutic outcomes. Applied Microbiology and Biotechnology, 92: 677-687. Gale, T. (1997). [online] Available at: http://www.encyclopedia.com/medicine/medical-journals/penicillin [Accessed 27 Oct. 2017]. Walsh, F. (2014). Superbugs to kill 'more than cancer'. [online] BBC News. Available at: http://www.bbc.co.uk/news/health-30416844 [Accessed 20 Oct. 2017]. Hoyert DL, Kochanek KD, Murphy SL. Hyattsville, Maryland: US Department of Health and Human Services, Public Health Service, CDC, National Center for Health Statistics, (1999). Deaths: final data for 1997. National Vitaln statistics reports. (vol. 47 no.19.) CDC Office of Infectious Diseases (OID) (2013). Antibiotic Resistance Threats in the United States. [online] p.15. Available at: https://www.cdc.gov/drugresistance/threat-report-2013/pdf/ar-threats-2013-508.pdf#page=5 [Accessed 17 Oct.
The Factor of War in the Development of Penicillin The discovery, development and subsequent use of penicillin can be considered to be one of the most important breakthroughs in medical history. There were many factors, which were involved in the development of penicillin, and it could be argued that war was the most important, but other factors were also responsible. Alexander Fleming was working in London as a bacteriologist in 1928 when he noticed that a growth of a mould called penicillin produced a substance that actually killed the germs he was working on. He realised that this might be very important and a year later he wrote an article about his findings. However, Fleming did not have the facilities or the support to develop and test his idea that penicillin could fight infection, and he didn't develop it further.
Penicillin, derived from the mold Penicillium, is the first antibiotic to successfully treat bacterial infections on humans. It was accidentally discovered by scientist, Alexander Fleming. While Fleming was growing Staphylococcus, a serious and often deadly infection, in a dish, he noticed the bacteria had stopped growing after a mold found its way
Years later other scientists were also intrigued by the possibilities of penicillin and produced enough penicillin to prove that it was a useable antibiotic. The scientists from Great Britain were developing all of this during World War II, and unfortunately funding for their drug was unavailable due to the war. They decided to bring their concepts to the United States, and once enough was made, it was eventually used, to treat wounded soldiers during World War I.
Thesis: With the advent of antibiotics in 1929 Fleming said, "The time may come when penicillin can be bought by anyone in the shops.Then there is the danger that the ignorant man may easily underdose himself and by exposing his microbes to non-lethal quantities of the drug make them resistant."With the overuse of antibiotics today we have seen this very idea come to be.Over usage is caused most prevalently by a lack of education on the part of the patient.Thus stated, the way to overcome such a circumstance is to educate, not only the patient but also the physician.
Penicillin: discovered by Alexander Fleming, helps treat a wide spectrum of infections that could potentially harm you. When penicillin was discovered, doctors finally had something that would completely cure their patients. Upon examining some colonies of Staphylococcus Aureus, Alexander Fleming noticed that a mold called Penicillium Notatum had grown in his petri dishes while he was on vacation. When Fleming put the dishes under the microscope, he found that the mold had stopped the growth of the Staphylococci. Fleming took a while longer to grow more of the mold to prove his findings he found that the mold inhabited the growth of bacteria, and that it could be used to fight infectious diseases. Alexander Fleming did not, however have the
Penicillin was one of the very first antibiotics. It is often referred to as "the miracle drug" because of its effectiveness against many harmful and deadly bacteria. With its discovery by Alexander Fleming in 1928, penicillin has proven to be a major contribution to the medical field. Penicillin is responsible for preventing the spreading of infectious illnesses, and for improving military medicine. It has revolutionized the study of medicine, saved countless of lives, and played a key role as a foundation for the development of other efficient antibiotics. The discovery of penicillin has greatly improved the way doctors were able to treat patients and gave way to a new era of antibiotics.
The widely used antibiotic medicine, Penicillin, was discovered all because of an accident that was made. When Alexander Fleming(a scottish physician) came back to his laboratory from a long vacation, found what would soon save millions of lives world wide. In an article written by Jesse Lane, it says that Fleming looked at a plate that was full of bacteria. But he also saw this yellow green mold, so he experimented and found that the ring was bacteria free, and that the mold was a rare spore called Penicillium notatum. In history penicillin is one of the earliest discovered widely used antibiotic agents. Penicillin became a medicine not by Alexander Fleming but by Dr. Howard Florey and Ernst Boris Chain. Penicillin then went on to save many lives in perfect time during the war.
Fleming’s most famous discovery, however, is that of penicillin, and again, it occurred quite by accident. Echoing the discovery of lysozyme, the story of penicillin begins with a contaminated bacterial culture, this time with a mold. Again, Fleming allowed the culture to mature, and found that the growth of the bacteria had been severely inhibited by the presence of the mold, which was later identified as a member of Penicillium. Fleming and his team did not, however, manage to convert the antibiotic into a useful form, so they shared the 1945 Nobel prize with the researchers that did.
Howard Florey was a British scientist who conducted research along with others on penicillin in the United States (Bellis). Key aspects described by Mary Bellis in “The history of Penicillin” emphasise that Florey’s research on penicillin helped “demonstrate penicillin's ability to kill infectious bacteria.” With further research done on penicillin, it was conceivable to use penicillin in beneficial ways. World War II boosted the intensity of the research on penicillin because, as stated by Brittany Connors in “The Discovery of Penicillin: The True Story”, “Part of the reason for their increased effort in discovering how penicillin could be used on humans was that a drug was needed to reduce bacterial infections in soldiers’ wounds.” Death from infected wounds was a common problem before antibiotics, such as penicillin. During the early development of penicillin as an antibiotic much progress was made. However, Florey and other scientists were having problems producing large quantities of the
In some cases, Penicillin can be the difference between life and death for some people. Having the luxury is dedicated to the discoveries from many scientists, Andrew Moyer and Alexander Fleming, in particular. This medicine has saved the lives of many American soldiers, and the allies as well during the tough times of World War II. The infectious diseases could have killed many without the discovery of penicillin. The discovery of the drug is life changing.
Penicillin is a rare type of mold that kills bacteria. The discovery of penicillin was made by a scientist named Alexander Fleming. Penicillin was actually discovered by accident when Alexander Fleming left his house for vacation and when he came back he found that there was mold on his dishes and he immediately examined the mold. Fleming was credited with the discovery of penicillin, Florey was credited with making it into a medicine, and Morey was credited with the mass production of penicillin. Most of the development of penicillin happened in the 1900’s but the discovery of penicillin was in 1890.
The discovery of penicillin, in 1928, was purely by accident. It was discovered by bacteriologist Alexander Fleming when he came back from vacation to his lab in London. He had left his lab in a mess and found that mold had grown on some plates he had left out in the open. Fleming noticed one plate in particular that had a ring around the mold. “After some experimentation, he found that the ring was bacteria-free, and that the mold was a rare spore called Penicillium notatum…” (Lane). Fleming grew the mold and discovered that it created a substance that had the property of killing many disease-causing bacteria. He named this substance penicillin and published his findings, noting that it may have value if produced in quantity
As we research deeper into the subject of antibiotic resistance we find there are a lot of interesting facts. First many bacterial infections and infectious diseases including HIV, gonorrhea, tuberculosis and many more are starting to become increasing difficult to treat using traditional antibiotics. About 90,000 patients die each year from their infections which has increased from 13, 300 deaths in 1992. People infected with resistant organisms have an increased likelihood of needing to go to the hospital and those who do will need to stay longer and might even require a more in-depth treatment. Antibiotic resistance is currently happening all over the world which causes new resistance mechanisms to form and spread everywhere. A high percentage of infections caught from hospitals are highly resistant infections are highly resistant infections. (1,
The production of penicillin shifted the use of antibiotics in the medical field. As one of the most common antibiotic substances, penicillin fights unwanted and harmful bacterias. Before it became a bacteria-reducing medicine, it began as mold sitting in a petri dish in the laboratory of Andrew Fleming. Numerous scientists such as Dr. Howard Florey and Andrew J. Moyer held significant positions in the widespread use of penicillin. Events leading up to the common use of penicillin began with the discovery, early development and the first uses, and the common purpose of the mold as a usable and effective medicine.
With its rising popularity and use, comes its abuse and frightening downsides (Davies, 2010). There are hundreds of antibiotics and to further complicate things, many people remain unaware and oblivious to their contribution to antibiotic resistance. Antibiotic resistance occurs when an antibiotic has lost its ability to effectively control or kill bacterial growth. In other words, the bacteria are "resistant" and continue to multiply in the presence of therapeutic levels of an antibiotic. It happens when an antibiotic kills the susceptible bacteria and the surviving bacteria are selectively pressured to survive and the genes mutate to evade and inhibit the functions of an antibiotic. It is very imperative in medicine that doctors and patients become more familiar with the repercussions that regard the abuse of antibiotics and how to take preliminary precautions to begin the fight against antibiotic resistance (Author Unknown,