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The Discovery of Antibiotics
Literature review on discovery of antibiotics
Antibiotic resistance review
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Antibiotic Resistance
John Pearson
Concepts of Biology
12/7/2014
Antibiotic resistance is basically when even after the use of antibiotics there are some bacteria that remains alive because it is immune to it, then that bacteria reproduces and reproduces until there is only the strongest bacteria left. Antibiotic resistance is generally a very big problem because it makes it so that bacterial infections and even diseases will eventually be very hard to nearly impossible to treat. Antibiotic resistance is almost entirely a human caused problem which could slowly be reversed over time. As we research deeper into the subject of antibiotic resistance we find there are a lot of interesting facts. First many bacterial infections
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Antibiotic resistance is generally a very big problem because it makes it so that bacterial infections and even diseases will eventually be very hard to nearly impossible to treat. Antibiotic resistance is almost entirely a human caused problem which could slowly be reversed over time. As we research deeper into the subject of antibiotic resistance we find there are a lot of interesting facts. First many bacterial infections and infectious diseases including HIV, gonorrhea, tuberculosis and many more are starting to become increasing difficult to treat using traditional antibiotics. About 90,000 patients die each year from their infections which has increased from 13, 300 deaths in 1992. People infected with resistant organisms have an increased likelihood of needing to go to the hospital and those who do will need to stay longer and might even require a more in-depth treatment. Antibiotic resistance is currently happening all over the world which causes new resistance mechanisms to form and spread everywhere. A high percentage of infections caught from hospitals are highly resistant infections are highly resistant infections. (1,
Adegoke AA, Tom M, Okoh AI, Jacob S (2010) Studies on multiple antibiotic resistant bacterial isolated from surgical site infection. Scient Res. Essays 5:3876-81.
Resistance arises from mutations that are not under the control of humans, but the evolution of bacteria has been sped along by the overexposure of antibiotics to both people and animals. The number of antibiotic-resistant strains of bacteria in an area is closely related to the frequency that antibiotics that are prescribed (Todar, 2012). Patients often unnecessarily demand antibiotics to treat common colds or simple illnesses that are not caused by bacteria. Instead, these infections are caused by viruses which, unlike bacteria, are unaffected by antibiotics. Incorrect diagnosis can also lead patients to using unnecessary antibiotics, which can sometimes be even more dangerous than otherwise left untreated. Besides the fact that antibiotics kill off beneficial bacteria in the intestines, misuse of antibiotics provides an opportunity ...
Antibiotic-resistant bacteria are created when mutations in the pathogen's genetic code occurs, changing the protein in the bacteria that the antibiotics normally go after into a shape that the antibiotic can not recognize. The average bacteria divides every twenty minutes, so if a contaminated spot has one single bacteria in the morning, there could be trillions on that same spot at the end of the day. That means that when counting all the possibilities of mutations, the amount of mutated offspring that the bacteria might have formed during those replications could be as high as in the millions. Fortunately though, this does not happen so frequently that it is normally an issue. The amount of non-mutated bacteria vastly outnumbers the mutated ones and many of the mutations occurring in the bacteria usually have either a harmful effect, or not effect at all on its function. That means that the pathogen is still relatively less harmful than it c...
This is the main reason antibiotic studies are disregarded. If the large majority of the population continues to do little to avert antibiotic resistance, bacteria will evolve beyond medical treatment. Actions must be taken by the community as a whole, and even further by the individual, to “reduce the spread of microbes and improve our defense against them” (Schmidt 272). Although antibiotic resistance is inevitable, humans are accelerating the natural defense of microbes through the overuse and misuse of antibiotics. The natural components of antibiotics have been used as local remedies long before humans understood the reasons why these sometimes-radical treatments worked.
Antibiotic resistance is one of the most important issues facing health care today, with wide reaching future implications if abuse continues. In the United States alone, antibiotic resistance is responsible for over two million illnesses and 23,000 deaths per year. Providers need to be judicious in the disbursement of these life saving pharmacological agents, while being informative of why antibiotics are not always the answer (Talkington, Cairns, Dolen, & Mothershed, 2014). In the case listed below, several issues need to be addressed including perception, knowledge deficit, and the caregiver’s role. This paper will focus on whether a prescription for antibiotics is appropriate and other courses of action that may be taken instead.
The Centers for Disease Control and Prevention (CDC), describes antibiotic resistance is the ability of bacteria or other microbes to resist the effects of antibiotic treatment. () So instead of being destroyed by the medications, the bacteria survives and continues to reproduce, resultant in new communicable diseases that even more difficult to treat.
One of the many growing concerns in the world today is antibiotic resistance. Antibiotic resistance happens when the bacteria that an antibiotic is made to treat learns how to fight the treatment, and develops a strain of DNA that resists the antibiotic. The resistance is then spread from generation to generation and from one bacteria to another bacteria. The article “Antibiotic Resistance Is Worrisome, but Not Hopeless” states that the misuse and overuse of antibiotics by humans is one of the reasons for the development of resistance but not the only reason. All in all, antibiotics are important to our country's public health. Education is one way that our country could aid the misuse and overuse of antibiotics that leads to resistance. The
Antibiotic resistance is a consequence of the misuse of antibiotics that give pathogenic bacteria the ability to withstand the effects of an antibiotic. Resistance occurs when bacteria change in such a way that they survive exposure to antibiotics. Resistance may not be confined to a single antibiotic, but may affect multiple antimicrobial classes. Antibiotic resistance is a major problem and everyone needs to work together to combat it - from medical practitioners to patients.
Throughout history disease has run rampant taking many lives with every passing day. Finding a cure or even just a tool in the battle has been the main focus of scientist throughout time. This focus is what brought us the discovery of antibiotics. Over the years antibiotics have been misused by patients, over prescribed by physicians and have led to resistant strains of bacteria.
Bacteria that is resistant to antibiotics is a major problem not only for the United States, but worldwide. According to the Centers for Disease Control and Prevention (2012) the cause is related to “widespread overuse, as well as inappropriate use, of antibiotics that is fueling antibiotic resistance”. According to World Health Organization (2013) resistance is a global concern for several reasons; it impedes the control of infectious diseases, increases healthcare costs, and the death rate for patients with resistant bacterial infections is twice of those with non-resistant bacterial infections.
If we don’t have antibiotics all bacteria reproduce at a similar rate. With the antibiotic the non-resistant individuals die but there is an increase in the resistant alleles. The genetic diversity is generated by rapid reproduction which because there is an increase rate of mutations which creates new alleles. It is also generated because bacteria can share DNA through gene transfer and they are also able to pick up DNA from the environment. This creates a threat to us because currently scientists have discovered at least one bacteria strain with resistance to each of the current
This turn of events presents us with an alarming problem. Strains of bacteria that are resistant to all prescribed antibiotics are beginning to appear. As a result, diseases such as tuberculosis and penicillin-resistant gonorrhea are reemerging on a worldwide scale (1). Resistance first appears in a population of bacteria through conditions that favor its selection. When an antibiotic attacks a group of bacteria, cells that are highly susceptible to the medicine will die.
The most effective way to combat pathogenic bacteria which invade the body is the use of antibiotics. Overexposure to antibiotics can easily lead to resistant strains of bacteria. Resistance is dangerous because bacteria can easily spread from person to person. Simple methods for preventing excessive bacterial spread are often overlooked. Not all preventative measures are even adequate. Doctors and patients often use antibiotics unnecessarily or incorrectly, leading to greater resistance. Antibiotics are used heavily in livestock and this excessive antibiotic use can create resistant bacteria and transfer them to humans. In order to reduce resistant bacteria,
Formal equality is known as the formal, legal equality. This is the equality that is seen as one law should be applied to all people, social and personal characteristics are no factor. Formal equality aims to distribute equality fairly and evenly, and aims to treat people the same. Formal equality does not ensure the wellbeing of individuals based on race, ethnicity, sex, age etc. Unfortunately, this side of equality does not recognize diversity and is insufficient for promoting social inclusiveness. Even though it may give the illusion of equality and justice, it is actually creating inequality and is actually ending up discriminating individuals (EU Charter of Fundamental Rights, 2004).
At his Nobel Peace Prize speech in 1945, Alexander Fleming warned against the misuse of antibiotics and the fact that by doing this, one allows the bacteria to ‘become educated’ and therefore become resistant to the antibiotic. It is believed that the first cases of antibiotic resistance were shortly after this speech. (Fleming, 1945)