Triphenylmethyl Bromide. A 400 mL beaker was filled with hot water from the tap. Acetic acid (4 mL) and solid triphenylmethanol (0.199 g, 0.764 mmol) were added to a reaction tube, with 33% hydrobromic acid solution (0.6 mL) being added dropwise via syringe. The compound in the tube then took on a light yellow color. The tube was then placed in the beaker and heated for 5 minutes. After the allotted time, the tube was removed from the hot water bath and allowed to cool to room temperature. In the meantime, an ice bath was made utilizing the 600 mL plastic beaker, which the tube was then placed in for 10 minutes. The compound was then vacuum filtered with the crystals rinsed with water and a small amount of hexane. The crude product was then weighed and recrystallized with hexane to form fine white crystals, which was triphenylmethyl bromide (0.105 g, 0.325 mmol, 42.5%). A Beilstein test was conducted, and the crystals produced a green to greenish-blue flame. …show more content…
Solid triphenylmethanol (0.200 g, 0.768 mmol) and sulfuric acid (2 mL) were added to a reaction tube, which was then ground using a glass rod until it dissolved and turned a dark orange color. The mixture was then added dropwise via a glass pipette into another reaction tube containing methanol (1 mL). An extra amount of methanol (2 mL) was used to transfer the rest of the contents of the first reaction tube. Formation of crystals was facilitated by scratching the side of the tube and adding additional methanol until the color changed to an off-white color. The contents of the tube were then vacuum filtered with water and the resulting crude product was weighed and then recrystallized using hot methanol to form triphenylmethyl methyl ether (0.051 g, 0.186 mmol, 24.2%). The melting point was 81 – 83˚
The goal of this experiment is to determine which products are formed from elimination reactions that occur in the dehydration of an alcohol under acidic and basic conditions. The process utilized is the acid-catalyzed dehydration of a secondary and primary alcohol, 1-butanol and 2-butanol, and the base-induced dehydrobromination of a secondary and primary bromide, 1-bromobutane and 2-bromobutane. The different products formed form each of these reactions will be analyzed using gas chromatography, which helps understand stereochemistry and regioselectivity of each product formed.
Then the reaction tube was capped but not tightly. The tube then was placed in a sand bath reflux to heat it until a brown color was formed. Then the tube was taken out of the sand bath and allowed to cool to room temperature. Then the tube was shaken until a formation of a white solid at the bottom of the tube. After formation of the white solid, diphenyl ether (2 mL) was added to the solution and heated until the white solid was completely dissolved in the solution. After heating, the tube was cooled to room temperature. Then toluene (2 mL) was added to the solution. The tube was then placed in an ice bath. Then the solution was filtered via vacuum filtration, and there was a formation of a white solid. Then the product was dried and weighed. The Final product was hexaphenylbenzene (0.094 g, 0.176 mmol,
The unknown bacterium that was handed out by the professor labeled “E19” was an irregular and raised shaped bacteria with a smooth texture and it had a white creamy color. The slant growth pattern was filiform and there was a turbid growth in the broth. After all the tests were complete and the results were compared the unknown bacterium was defined as Shigella sonnei. The results that narrowed it down the most were the gram stain, the lactose fermentation test, the citrate utilization test and the indole test. The results for each of the tests performed are listed in Table 1.1 below.
The isomerization procedure was done in order to create dimethyl fumarate from dimethyl maleate. Dimethyl maleate and dimethyl fumarate are cis and trans isomers, respectively. This procedure was done via a free radical mechanism using bromine. The analysis of carvones reaction was done in order to identify the smell and optical rotation of the carvone samples that were provided. The odor was determined by smelling the compound and the optical rotation was determined using a polarimeter.
Procedure: Anisole (0.35mL, 0.0378mol) was obtained and placed in a pre-weighed 25 mL round bottom flask, along with 2.5 mL of glacial acetic acid and a magnetic stir bar. Then the reaction apparatus was assembled, the dry tube was charged with conc. sodium bi sulfate, the 25 mL round bottom was attached to the apparatus, and 5 mL of Br2/HBr mixture was obtained and placed in the round bottom. The reaction took place for 20 minutes. An orange liquid was obtained and placed in a 125 mL Erlenmeyer flask along with 25 mL of water and 2.5 mL of conc. Sodium bisulfate soln. The solution was then placed in an ice bath to precipitate and then the solid product was filter in a Buchner funnel. These crystals were then re-dissolved minimum amount of hot solvent (heptane) and recrystallized. Once a dry product was obtained, a melting point was established (2,4-Dibromoanisol mp 55-58 C) and percent yield was established (52%).
While the solution is being stirred, an air condenser is attached to the vial and 12.2 mg of NaBH4 is added in 3 portions through the condenser. The condenser is capped with a drying tube containing calcium chloride and cotton. After thirty minutes a TLC analysis is taken of the reaction to see how many compounds are present. Three compounds were identified on the TLC meaning that the reaction did not go to completion and the mixture was placed back on a hot plate to react further for ten minutes longer. The TLC showed the starting product 4-tert-butylcyclohexanone and the cis-/trans- forms of 4-tert-butylcyclohexanol; the cis isomer is more polar and will appear above the trans
The goal of this lab is to exemplify a standard method for making alkyne groups in two main steps: adding bromine to alkene groups, and followed by heating the product with a strong base to eliminate H and Br from C. Then, in order to purify the product obtained, recrystallization method is used with ethanol and water. Lastly, the melting point and IR spectrum are used to determine the purity of diphenylacetylene.
This week’s lab was the third and final step in a multi-step synthesis reaction. The starting material of this week was benzil and 1,3- diphenylacetone was added along with a strong base, KOH, to form the product tetraphenylcyclopentadienone. The product was confirmed to be tetraphenylcyclopentadienone based of the color of the product, the IR spectrum, and the mechanism of the reaction. The product of the reaction was a dark purple/black color, which corresponds to literature colors of tetraphenylcyclopentadienone. The tetraphenylcyclopentadienone product was a deep purple/black because of its absorption of all light wavelengths. The conjugated aromatic rings in the product create a delocalized pi electron system and the electrons are excited
Benzyl bromide, an unknown nucleophile and sodium hydroxide was synthesized to form a benzyl ether product. This product was purified and analyzed to find the unknown in the compound. A condenser and heat reflux was used to prevent reagents from escaping. Then the solid product was vacuum filtered.
The reaction performed in this experiment was bromination of an alkene, using trans-Cinnamic acid, Pyridinium Tribromide, and Glacial Acetic Acid.
DH=-285.5 kJ/mol. In this investigation, we will be working with potentially dangerous chemicals and safety precautions must be made. Magnesium oxide is a respiratory and eye irritant, the dust must not be inhaled and all work with MgO should be conducted in the fume hood ( Cartwright, 2002). Hydrochloric acid is extremely corrosive, inhalation of the vapor can cause serious injury, ingestion could be fatal, and the liquid can cause severe damage to the skin and eyes; when working with HCl splash goggles and gloves should be worn, and work should be conducted in a well ventilated area (Cartwright, 2002). Materials and Methods --------------------- Goggles - Lab apron - Magnesium oxide MgO - 1g. Lab balance 100mL graduated cylinder Hydrochloric acid HCl - 200mL/.5M. - 2 plastic foam cups - thermometer - cover for cup - Magnesium (Mg) ribbon - 600mL beaker (base for calorimeter) - 400mL beaker (transportation of acid).
The goal of this lab is to synthesize maleic anhydride with polyethylene glycol of 200g/mol molecular weight (PEG 200) and 2,3-dimethyl-1,3-butadiene to get 4,5-dimethylcyclohexane-1,2-dicarboxylic acid anhydride and its diacid by using Diels-Alders reaction and hydrolysis, respectively. The crystals were determined using melting point determination and IR spectroscopy.
The purpose of this experiment involved synthesis of diphenylmethanol using phenylmagenisum bromide and benzaldehyde, using the method called Grignard reaction. Grignard reactions are an important method for new carbon-carbon bond formation as well as for the synthesis of alcohols.
Ensure gloves are worn at all times when handling strong acids and bases within the experiment of the preparation of benzocaine. 4-aminobenzoic acid (3.0g, 0.022 moles) was suspended into a dry round-bottomed flask (100cm3) followed by methylated sprits (20 cm3). Taking extra care the concentrated sulphuric acid of (3.0 cm3, 0.031 moles) was added. Immediately after the condenser was fitted on, and the components in the flask were swirled gently to mix components. It should be ensured that the reactants of the concentrated sulphuric acid and the 4-aminobenzoic acid were not clustered in the ground glass joint between the condenser itself and the flask. In order to heat the mixture to a boiling point, a heating mantle was used and then further left for gently refluxing for a constituent time of forty minutes. After the duration of the consistent forty minutes the rou...
The medication of paracetamol can be administered in various ways and they are sold in different formulations. The common dosage comes in tablets form of 500 mg, in dispersible fizzy tablets (500 mg) and oral suspensions. It can also be bought in capsules as a mixture with other API like caffeine and codeine.