Importance Of Natural Products

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Natural products, in general terms, are chemical substances produced in nature1. Or simply putting it, they are molecules found in living organisms, according to Mcmurry2. Natural products are secondary metabolites, which are small molecules living in the organism without effecting in a major way, like nucleus acids, which are essential for the survival of the organisms19. While many of them don’t have a specific biological role, some of them act as sex attractants and anti-feedants19. They differ with other biological micro molecules in their complexity, since they are much smaller than average micro molecule, tend to be more diverse and have the ability to conserve themselves for a long period of time even without a specific biological activity or role19. The importance of natural products relay on its variety of uses, since natural products are used in pharmaceutical industry, food production and pesticides3. The techniques commonly used to produce natural products are: Column chromatography, extraction and distillation. In this paper, the efficiency of the extraction method in synthesizing natural products will be evaluated. Extraction of natural products in an economic and environmentally-friendly way is of high importance to all industries involved. Extraction is a “very common laboratory procedure used when isolating or purifying a product. 5. it’s one of the ancient techniques that humans developed to extract liquid from solid natural product6. The most famous example is the making of coffee, in which water is used as the liquid6. The caffeine, because of its molecular weight and polarity, will dissolve in the hot water and to be removed. Solid-liquid extraction will be discussed today regarding extracting pipperine from b... ... middle of paper ... ...elting point was a strong indication of peperine presence, it was recorded at 125-131oC, which is a range that contains the literature value (130oC). Finally, the MS was also very helpful to proving that piperine was obtained since it recorded the MW as 285, which is the exact value obtained in a different literature12. Overall, the experiment was very successful. Although the recovery percentage is small (8.07%), but the fact is that is alkaloids represent 9% of the total mass of the pepper, doesn’t appear to be a big deal . In addition, the NMR was helpful in identifying different hydrogens but with uncertainty. That’s why a 400 NMR was needed. To improve the results in the future, a nitrogen stream should be used to dry the product to eliminate any H2O contaminant. Also, an increase in the time of the refluxing process would produce better percentages of recovery

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