Lymphomas are malignancies of the lymphoid tissue, which includes the lymphocytes, lymph nodes, the spleen and bone marrow (Pearson, 2015). The two types of lymphomas are Hodgkin’s lymphoma and Non-Hodgkin’s lymphoma (NHL). Unlike Hodgkin’s lymphoma, the cells of NHL do not contain the Reed-Sternberg cell. Instead, this disease involves lymphoctyes (B, T, or Natural Killer cells) in various stages of development and may mimic a leukemia (Lewis et al, 2016 ). Nearly 70,000 people are diagnosed with Non-Hodgkin’s lymphoma in the United States each year (Sommers & Fannin, 2015). Although the definite cause of NHL is unknown, chromosomal abnormalities and exposures to viruses and infections are suspected as some. Non-Hodgkin’s lymphoma
On Sunday, a nurse on a medical/surgical floor in a large private hospital is assigned as the primary nurse to a woman who was just admitted. The woman’s testing begins on Monday and the primary nurse does not have work for the next few days. The nurse returns on Saturday and goes over the woman’s charts. The nurse discovers that the woman has chronic lymphocytic leukemia and is being treated for the disease. After approaching the woman the nurse realizes that the woman is unaware of her diagnoses as she asks the nurse when she will be able to return to work. The nurse explains that she has not yet spoken with the physician and will get back to her once she has done so. On your way back to the nurses' station, one of the woman's two daughters approaches the nurse and urges the nurse to assure her mother that there is no reason for concern. The daughter explains that her mother has just been through a painful divorce and
Hodgkin 's Lymphoma occurs when following a mutation in the lymphocyte DNA. The mutation occurs after birth, meaning that Hodgkin’s disease is not hereditary. The mutated DNA can lead to the uncontrolled growth of cancerous lymphocytes if untreated. The cancerous lymphocytes produce tumor masses in the lymph
The World Health Organization (WHO) classifies Hodgkin’s lymphoma into two different groups: nodular lymphocyte predominant (NLPHL) and classical HL (cHL). NLPHL develops slowly, is found predominantly in males, and accounts for about 5% of all HL cases. It is characterized by L&H cells and a different antigenic profile (Roddle, Peggs, 2009, p. 208). In contrast, cHL, the most common subtype, comprises nearly 80% of diagnosed cases. Classical HL is divided into four subtypes. “The diagnosis is dependent on the pathological finding of H...
Lymphedema is an abnormal collection of lymphatic fluid and swelling caused by several removal, obstruction, and damage to the lymph nodes which is part of the cancer. The Majority of the swelling happen in the arm or legs may occur in any other body parts. Lymphedema disease can be developed when a lymph vessel is damaged or clogged. Usually the lymph liquid is carried out the body system by a lymph vessel. Although the protein rich fluid is collects in certain areas, they can seduce more liquid and increase swelling. Sometimes the lymphedema commonly confused with lip edema, abnormal fat cells, which can expand onto secondary lymphedema.
Leukemia and Lymphoma Society (LLS) is the worlds largest non-profit organization which funds blood cancer research and providing patient services and education. The LLS mission is to cure leukemia, lymphoma, Hodgkin's lymphoma and myeloma and to improve quality of patients and there families. This is done by discovering new cures and making blood cancers a story of the past.The organizations national office is located in White Plains, NY. Leukemia and Lymphoma Society has local chapters through out the United States and Canada.
Non Hodgkin Lymphoma (NHL) is a type of cancer that affects the lymphatic system. Our lymphatic system helps to protect us from disease and infection and consists of: lymph nodes, plasma cells, lymphatic vessels, the spleen, thymus gland, tonsils, adenoids, bone marrow, and immunoglobulins. White blood cells called Lymphocytes, travel through the body via lymphatic vessels and help to trap and kill disease and infection. Lymphatic vessels connect to lymph glands in our bodies and collect into large ducts that empty into our blood stream. Lymphocytes enter the blood stream through these ducts. There are three main types of Lymphocytes. B lymphocytes (B cells) make antibodies in response to invading bacteria, viruses or other microbes. B lymphocytes
Immunotherapies combat cancer by utilizing the body’s own immune system. By activating the immune system to specifically target cancer cells, many of the side effects of conventional chemotherapies due to the nonspecific killing of healthy cells, such as hair loss, are avoided. The most common non-Hodgkin lymphoma (NHL) is Diffuse large B-cell lymphoma (DLBCL), which comprises approximately 30% of all new diagnoses.1 The median age of those presenting is mid-60s. The cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) chemotherapy regimen has been the foundation of treatment since its development in the 1970s.2 CHOP has remained the standard of care since attempts to improve outcomes with more intensive chemotherapy regimens failed
The poster presentation was presented by Martina Martin, a senior who is a Clinical Lab Science major at UIS. Her presentation was titled “Take Back Your Stem Cells: The Key to Treatment of Peripheral T Cell Lymphoma” and it explains how your own stem cells can help treat and cure a rare form of Non-Hodgkin's Lymphoma. Martina’s purpose of this experiment was to find the best treatment option for this patient that would be the least impactful on the patient. What happened is that a perfectly healthy 67 year old female suddenly started getting scabbing and itchy rashes all her her skin while in the Dominican Republic in January.
Hodgkin disease is a type of lymphoma, a cancer that starts within white blood cells, called lymphocytes; a cancer of the lymphatic system. Lymphatic system is the network of vessels through which lymph drains from the tissues into the blood. The lymphatic system is a network of nodes connected by vessels that drain fluid and waste products from the body. The lymph nodes act as tiny filters, straining out foreign organisms and cells. Nodes are knots of tissue. Which is part of the immune system; named after the doctor who first recognized it, which is Dr. Thomas Hodgkin. This cancer is rare, between twenty thousand to two hundred thousand U.S. cases per year and also known as Hodgkin's lymphoma.
Chronic lymphocytic leukaemia(CLL)is a common adult leukaemia that results from proliferation of neoplastic B- lymphocyte clones. The disease is most frequent in patients over the age of 60 and has a variable clinical course. A variety of genetic aberrations can drive the leukaemia and also initiate the transformation into high grade malignancy.
Hodgkin's and Non-Hodgkin's Lymphoma: Differences? and similarity on MedicineNet.com. Retrieved December 9, 2013, from http://www.cdl.gov http://www.medicinenet.com/script/main/art.asp?articlekey=79261 Turley, Susan M. (2014). The 'Path of Medical language (third ed.). Upper Saddle River, NJ: Pearson. Education & Training, Inc. Zimmerman, K. A. & Co.,
The lymphatic system is a link of tissues and organs that help clear the poisonous toxins, waste and further unwanted elements that are inside the human body. The key function of the lymphatic system is to transport lymph which is a watery fluid substance holding infection that are fighting white blood cells, all over the human body.
The Phase I trial will be discussed here as it pertains to the topic at hand. The typical treatment for cervical cancer if surgery is not a viable option – like if the cancer has spread, then called locally advanced cervical cancer – is chemotherapy and radiation treatment at the same time. This phase I clinical trial is simply looking to add ipilimumab to this regimen, but once the chemo/radiation has been completed (LACC article). Chemo and radiation destroy tumor cells, which causes tumor-associated antigens to be released. Once released, these antigens are exogenous (outside the cell) and will be presented to helper T cells to initiate an immune response.
The Lymphatic System consists of tissues and organs such as the tonsils, thymus, lymph nodes, lymph glands, lymphatic vessels, spleen, Peyer’s Patches (found in the small intestine), appendix, bone marrow and lymph. These are the states of the lymphatic system when it is in a healthy state. The lymphatic system works with the immune system in providing the body protection from harmful diseases and infections. The lymphatic system regulates interstitial fluid protein. Its function is not to produce erythrocytes however to dispose of them.
Acute lymphocytic leukemia, or ALL, is a type of cancer that starts in the bone marrow where early blood cells are made. It is also called acute lymphoblastic leukemia. (American Cancer Society, 2016). Leukemia is cancer of the blood and the blood forming tissues. It is characterized by overproduction of lymphocytes. Acute leukemias involve lymphocytes that grow rapidly, but abnormally (Leukemia, 2016). According to American Cancer Society (2016), “The term ‘acute’ means that the leukemia can progress quickly, and if not treated, then it could be fatal within a few months. Lymphocytic means it develops from early forms of lymphocytes, a type of white blood cells.”