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Case study of hodgkin's disease
Case study of hodgkin's disease
Case study of hodgkin's disease
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Hodgkin disease is a type of lymphoma, a cancer that starts within white blood cells, called lymphocytes; a cancer of the lymphatic system. Lymphatic system is the network of vessels through which lymph drains from the tissues into the blood. The lymphatic system is a network of nodes connected by vessels that drain fluid and waste products from the body. The lymph nodes act as tiny filters, straining out foreign organisms and cells. Nodes are knots of tissue. Which is part of the immune system; named after the doctor who first recognized it, which is Dr. Thomas Hodgkin. This cancer is rare, between twenty thousand to two hundred thousand U.S. cases per year and also known as Hodgkin's lymphoma.
Lymphoma occurs when the lymph node cells or
On Sunday, a nurse on a medical/surgical floor in a large private hospital is assigned as the primary nurse to a woman who was just admitted. The woman’s testing begins on Monday and the primary nurse does not have work for the next few days. The nurse returns on Saturday and goes over the woman’s charts. The nurse discovers that the woman has chronic lymphocytic leukemia and is being treated for the disease. After approaching the woman the nurse realizes that the woman is unaware of her diagnoses as she asks the nurse when she will be able to return to work. The nurse explains that she has not yet spoken with the physician and will get back to her once she has done so. On your way back to the nurses' station, one of the woman's two daughters approaches the nurse and urges the nurse to assure her mother that there is no reason for concern. The daughter explains that her mother has just been through a painful divorce and
The Hematologic System is regarded as the body’s system that regulates the movement of nutrients, molecules (macro and micro molecules), and oxygen to tissues and metabolic waste products and carbon dioxide out of the tissues (Colbert, 2009). The overall role of the hematologic system is to deliver substances needed for cellular metabolism, temperature regulation, defend the body from injury and microbial infections, and maintain the homeostatic balance or acid-base chemistry of the blood and fluid-electrolyte balance. The Hematologic System is principally made up of the blood, blood vessels, and primary organs that manufacture blood cells such as the bone marrow, spleen, lymph nodes, liver, and thymus gland (Ignatavicius & Workman, 2009). Blood is made up of three distinct components: red blood cells, white blood cells, and plasma, and its role is to transport necessary substances for metabolism (nutrients, hormones and oxygen) to cells and to remove metabolic waste products and carbon dioxide, regulation of body temperature and fluid balance, and protect the body from infections. Blood vessels simply aid the transportation of blood throughout the body, simply in and out of the heart. Spleen on its part is the largest lymphatic organ and functions as the blood filtration system and reservoir, site for fetal hematopoiesis, and mounts immune responses that act against invading infections. Bone marrow is another important component of the hematologic system, and its role is to synthesize new blood cells (Red blood cells white blood cells, and platelets) that constitute a healthy blood count while the liver functions by detoxifying the blood (Colbert, 2009).
Hodgkin 's Lymphoma occurs when following a mutation in the lymphocyte DNA. The mutation occurs after birth, meaning that Hodgkin’s disease is not hereditary. The mutated DNA can lead to the uncontrolled growth of cancerous lymphocytes if untreated. The cancerous lymphocytes produce tumor masses in the lymph
When cells in the lymphatic system grow at an abnormal rate, it creates a malignant tumor, Cancer. Hodgkin lymphoma and Non- Hodgkin lymphoma are both cancers that originate in white blood cells, in the lymphatic system. The system is responsible for fighting infection, bacteria, viruses, and removing damaged cells by producing lymphocytes (a type of white blood cell that is important to the immune system; they decide how the immune system will respond to infections or any an familiar organism). The system also communicates with the blood circulatory system by transporting lymph (a clear fluid that carries lymphocytes, waste, and excess fluid from tissues back into the blood system through the thoracic duct.)
Cancers arising from the lymph nodes or other sites of lymphoid tissue are broadly termed lymphomas. This group of diseases is divided into Hodgkin’s disease and non-Hodgkin’s lymphoma. In both conditions, there is a replacement of normal lymphatic tissue by collections of abnormal lymphoma cells.
Hodgkin’s lymphoma is a cancer of the lymph nodes of the lymphatic system; this system is an important part of the body because the cancer can use the lymphatic system to travel around the whole body.
Hodgkin’s lymphoma is a form of cancer in the lymphatic system. This type of lymphoma originates in the white blood cells, and spreads throughout the lymph nodes in the body. The cause of Hodgkin’s lymphoma is unknown, and it is sometimes found by chance. This disease is typically treated with chemotherapy and radiation and, if found in the early stages, the patient has a good chance of being fully cured.
Cancer is the term used to describe a group of diseases consisting of hundreds of ailments and although there exists so many different types of cancer, they all begin in a similar way. The body is made up of over a trillion cells, and cancer is the uncontrolled growth of malfunctioning cells in the body (Dawson, 1996). “Normal body cells grow, divide, and die in an orderly fashion. During the early years of a person’s life, normal cells divide faster to allow the person to grow. After the person becomes an adult, most cells divide only to replace worn-out or dying cells or to repair injuries” (American Cancer Society, 2012).
Leukemia and Lymphoma Society (LLS) is the worlds largest non-profit organization which funds blood cancer research and providing patient services and education. The LLS mission is to cure leukemia, lymphoma, Hodgkin's lymphoma and myeloma and to improve quality of patients and there families. This is done by discovering new cures and making blood cancers a story of the past.The organizations national office is located in White Plains, NY. Leukemia and Lymphoma Society has local chapters through out the United States and Canada.
What is Leukemia? Leukemia is a cancer in blood forming cells that are in early stages of development. Most of the time the white blood cells, but some types of leukemia start in other types of blood cells. Blood cells are form in bone marrow. Any of these cells can turn into a leukemia cell, once this happens the cell does not mature like it should. The cell may start to produce rapidly and the mutated cells probably won’t go through apoptosis like they should. These cells build up in the bone marrow and crowd out the healthy cells. Typically, leukemia cells get into the blood stream rather quickly. From the blood stream they can spread to places like lymph nodes, spleen, liver, central nervous system or other organs where the leukemia cells can cause those other cells to function irregularly.
The emphasis on health and fitness has become paramount in our society today in an effort to prevent and combat diseases such as Cancers. Cancers are a group of over 100 diseases that affects every aspect of the human system from skin, to bones, to muscles, to blood. One of the most common blood disorders is Leukemia. As defined by the U.S. National Library of Medicine, Leukemia is a type of blood cancer that begins in the bone marrow. The bone marrow is the soft tissue in the center of the bone that is responsible for the production of blood cells. The term leukemia means white blood. The term leukocytes refer to white blood cells, which are body’s defense against infections and other foreign substances. When Leukemia occurs there is an uncontrolled increase in the number of white blood cells. When this occurs, these cancerous cells inhibit the production of healthy red blood cells, platelets, and mature white blood cells. Over time the cancerous cells can spread to the bloodstream and lymph nodes. They can also travel to the Central Nervous System and the rest of the body.
Leukemia is a cancer of the white blood cells. It begins in the bone marrow, the soft tissue inside the bones. Within the bone marrow is where white blood cells are created, that help fight off bacteria, viruses, and other microorganisms within the body that cause infections. The disease develops to when the white blood cells are being produced out of control. The cells that are being produced do not work properly as they should, they grow faster than a normal cell would and don’t know when to stop growing. Overtime, if not treated properly, the white blood cells will over crowd blood cells, creating a serious problem such as anemia, bleeding and infection. Leukemia cells can spread to the lymph nodes and other organs in the body causing swelling and pain.
Acute myeloid leukemia (AML): AML affects myeloid cells and grows quickly. More common in adults.
Hodgkin's and Non-Hodgkin's Lymphoma: Differences? and similarity on MedicineNet.com. Retrieved December 9, 2013, from http://www.cdl.gov http://www.medicinenet.com/script/main/art.asp?articlekey=79261 Turley, Susan M. (2014). The 'Path of Medical language (third ed.). Upper Saddle River, NJ: Pearson. Education & Training, Inc. Zimmerman, K. A. & Co.,
The Phase I trial will be discussed here as it pertains to the topic at hand. The typical treatment for cervical cancer if surgery is not a viable option – like if the cancer has spread, then called locally advanced cervical cancer – is chemotherapy and radiation treatment at the same time. This phase I clinical trial is simply looking to add ipilimumab to this regimen, but once the chemo/radiation has been completed (LACC article). Chemo and radiation destroy tumor cells, which causes tumor-associated antigens to be released. Once released, these antigens are exogenous (outside the cell) and will be presented to helper T cells to initiate an immune response.