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Briefly discuss biofilms
Biofilms microbiology
Biofilms microbiology
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Introduction
Biofilms are complex communities of microorganism that can adhere to living or non-living surfaces. In the environment, biofilms divide by attaching and growing on surfaces. They are found in soil, aquatic system, medical devices, living tissues such as tooth, heart valves, ears and lungs. Biofilm formation is a process where the planktonic bacteria comes in contact with a surface, and producing the extracellular polymeric matrix to protect themselves against immune cells and antimicrobials (Chauchan et al., 2009). There is a difference between a planktonic bacteria, and a bacterial biofilm. The planktonic bacteria, moves around freely, and it is single celled organism; is responsible for acute bacterial infections. It can not change genetic activity. The bacterial biofilms are multi-cellular organisms, it can initiate a change in genetic activity. Biofilms are very important, because they can create energy loses, equipment damage, contamination,
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These infections are leading cause of healthcare-associated infections. According to NIH, 80% of all chronic infections are biofilm related. And according to CDC, 65 % of all microbial infections are directly related to the growth of the biofilms. Biofilms are very important for public health due to some of the biofilms, which exhibit decreasing susceptibility to antimicrobials. Biofilms are found nearly everywhere, and have a major impact on the health and well-being of humans along with health industries. Most biofilms are in a benign, slippery coating formation but others may cause serious damage to the health of an individual. A significant concern that sticks out to individuals is the contamination of medical utensils and devices such as urinary catheters, implants, etc. Biofilms can also cause nosocomial infections. Nosocomial infections are infections retrieved from a hospital setting, or hospital acquired infections
The resistance to many antibiotics is a well-known property of bacterial biofilms. Biofilms are dense...
During her presentation, Bonnie Bassler expends many different aspects of communication in a bacterial level and how successful communication is important to survival and efficient functioning. It is evident from her presentation that without a common language to communicate with, bacteria could not work as efficiently as they do, neither to immunize people nor create havoc in them. In her presentation, Bassler asserts the importance of the use of language in communication in bacteria, using rhetorical appeals – logical, ethical and emotional – and how it is consequently related to humans.
The great Martin Scorsese directs the highly controversial movie The Wolf Of Wall Street. The movie is based on the true story of Jordan Belfort, played by Leonardo DiCaprio. In the early 1990s Belfort uses knowledge he acquired by Mark Hanna, played by Matthe McConaughey to perform the biggest securities scam of the time. With his team Belfort becomes a prosperous stockbroker who will do anything to stay at the top. The Wolf of Wall Street reveals the human condition’s obsession with money and power, which inevitable leads down a self-destructive journey.
Every human has microbiomes that are personalized for the individual and are extremely important to maintaining a good health standing, however, these microbiomes can be capable of contracting a disease. One of the most common areas for these microbiomes to contract something that could be harmful to the person’s health is called the oral microbiomes, which are found in the mouths of humans. Within the biofilms of the oral cavity, rests these oral microbiomes that maintain a healthy equilibrium in the mouth. However, if not taken care of properly, oral microbiomes can be taken over by a pathogen that can quickly turn the state of the person’s mouth from a healthy equilibrium to a very unhealthy equilibrium (1). Some bacteria found in the oral cavity can be an extremely danger.
Streptococcus mutans is a gram positive cocci shaped bacteria. It is a facultative anaerobes. Streptococcus mutans is found in the oral cavity and now can be found in the heart tissue and valves. Considering the fact that Streptococcus mutans is a facultative anaerobe the bacteria is often found in between your teeth, around your gum line, and on your occlusal surfaces. Streptococcus mutans lives in temperatures that range from eighteen to forty degrees celsius falling into the mesophile category. Streptococcus mutans changes the environment by adhering to a bio-film layer produced on the enamel surface of your teeth from such things including: acidic foods that contain sugars and starch, drinks that contain carbonation and sugars, whiting products, tobacco use, and lack of oral home care. The first virulence factor is dependent on the synthesis of water-soluble glycans from the disaccharide sucrose. By breaking down the glycogen this allows help for bacteria adhere better. Next virulence factor, Streptococcus mutans has the ability to become more acid tolerant and cell to cell communication. Once the bacteria is colonized in the bio-film it starts to produce an acidic environment below a ph of 7.(Kreth, et al., 2008) By doing so, Streptococcus mutans out competes any other organism living on the teeth or in the oral cavity. This leads to the third factor, which displays a production of lactic acid fro...
This literature review will analyze and critically explore four studies that have been conducted on hand hygiene compliance rates by Healthcare workers (HCWs). Firstly, it will look at compliance rates for HCWs in the intensive care units (ICU) and then explore the different factors that contribute to low hand hygiene compliance. Hospital Acquired infections (HAI) or Nosocomial Infections appear worldwide, affecting both developed and poor countries. HAIs represent a major source of morbidity and mortality, especially for patients in the ICU (Hugonnet, Perneger, & Pittet, 2002). Hand hygiene can be defined as any method that destroys or removes microorganisms on hands (Centers for Disease Control and Prevention, 2009). According to the World Health Organization (2002), a HAI can be defined as an infection occurring in a patient in a hospital or other health care facility in whom the infection was not present or incubating at the time of admission. The hands of HCWs transmit majority of the endemic infections. As
Biofilms are formed by a six step process. First is a reversible process, when an organic monolayer(made of polysaccharides or glycoproteins) absorbs to the surface, altering the chemical and physical properties of the surface. This makes the surface more conditioned and increase the chance that planktonic bacteria will attach. Secondly, also a reversible step, is when the free-floating or planktonic bacteria encounter the conditioned surface, and some attachment of the bacteria may occur. The third step is when the bacteria is left attached too long, then an irreversible attachment occurs. F...
(2014) shed light on two key components for infection control, which includes protecting patients from acquiring infections and protecting health care workers from becoming infected (Curchoe et al., 2014). The techniques that are used to protect patients also provide protection for nurses and other health care workers alike. In order to prevent the spread of infections, it is important for health care workers to be meticulous and attentive when providing care to already vulnerable patients (Curchoe et al., 2014). If a health care worker is aware they may contaminate the surroundings of a patient, they must properly clean, disinfect, and sterilize any contaminated objects in order to reduce or eliminate microorganisms (Curchoe et al., 2014). It is also ideal to change gloves after contact with contaminated secretions and before leaving a patient’s room (Curchoe, 2014). Research suggests that due to standard precaution, gloves must be worn as a single-use item for each invasive procedure, contact with sterile sites, and non-intact skin or mucous membranes (Curchoe et al., 2014). Hence, it is critical that health care workers change gloves during any activity that has been assessed as carrying a risk of exposure to body substances, secretions, excretions, and blood (Curchoe et al.,
Nursing diagnosis Hospital acquired infections are spread by numerous routes including contact, intravenous routes, air, water, oral routes, and through surgery. The most common types of infections in hospitals include urinary tract infections (32%), surgical site infections (22%), pneumonia (15%), and bloodstream infections (14%). a. (book). The most common microorganisms associated with the types of infections are Esherichila coli, Enterococcus species, Staphylococcus auerus, Coagulase-negative staphylococci, or Pseudomonas aeruginosa. Urinary tract infections occur when one or more microorganisms enter the urinary system and affect the bladder and/or the kidneys.
Multiplication of attached organisms leads to confluent growth and biofilm formation. Adherent bacteria synthesise extracellular polymers.
Biofilms can form on many surfaces, including natural aquatic systems, human teeth, medical devices like artificial heart valves and catheters,
Leboffe, M. J., & Pierce, B. E. (2010). Microbiology: Laboratory Theory and Application, Third Edition 3rd Edition (3rd Ed.). Morton Publishing
“Researchers in London estimate that if everyone routinely washed their hands, a million deaths a year could be prevented” (“Hygiene Fast Facts”, 2013, p. 1). Hands are the number one mode of transmission of pathogens. Hands are also vital in patient interaction, and therefore should be kept clean to protect the safety of patients and the person caring for the patient. Hand hygiene is imperative to professional nursing practice because it prevents the spread of pathogens, decreases chances of hospital-acquired infections, and promotes patient safety. There is a substantial amount of evidence that shows why hand hygiene is important in healthcare
Infectious diseases are the disorders caused by organisms such as bacteria, viruses, fungi or parasite who live both inside and outside our bodies and are normally helpful but can cause infectious diseases to the human (body) system under certain conditions. And for a disease to be infectious, there is what is called ‘’chain of infection’’ that takes place before. And this can be seen in the below diagram:
Microbes are everywhere in the biosphere, and their presence invariably affects the environment in which they grow. The effects