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Pancreas anatomy hesi
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There is the serosa, which is the outermost layer and it keeps the surfaces moist. The there is the muscle layer, which contains the circular muscular layer and the longitudinal muscle layer. These muscles contract and relax to move the chyme throughout the intestinal tract. Then comes the submucosa which has the blood and lymphatic vessels and nerves. Finally, the inner layer is the mucosa which is a layer of epithelial cells on a base of connective tissue and smooth muscle. It has villi and fold that are called plicae and circulares.
2. Describe the common tissues and structures found in accessory organs. (4 points)
Common tissues and structures found in accessory organs are ducts that secrete created digestive enzymes, like the pancreatic duct, collecting ducts from salivary glands, and the gallbladder that receives bile through the cystic duct. Accessory organs also have cells that produce either enzymes of hormones. Pancreatic acinar cells creates digestive enzymes whilst Islets of Langerhans secrete insulin and glucagon. Parotid and submandibular glands produce digestive enzymes and sublingual glands secrete a mucous saliva. Finally, hepatocytes produce digestive bile.
3.
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Describe these structures and their function in the pancreas: (6 points)
- Acinar cells that secrete enzymes or bicarbonate
- These cells are found in the pancreas and the secrete digestive enzymes or bicarbonate into ducts that feed into the main pancreatic duct.
- Islet cells that secrete insulin or glucagon - These cells are endocrine cells that secrete the hormones insulin and glucagon directly into the capillary network that is also connected with the pancreatic duct. Insulin and glucagon affect blood sugar levels.
- Blood
The beta cells affect a person’s glucose regulations within the blood. This is because the beta cells are in charge of sending insulin arou...
mucous layer of the organs in the digestive tract by means of enzymes and acids.
This is monitored by the cells within the Islets of Langerhans, which is located in the control (the pancreas). After skipping a meal or tough physical exercise blood glucose concentration decreases. Alpha cells in the islets detect this drop and are stimulated to secrete glucagon. Glucagon is a polypeptide hormone which influences an increase in blood glucose concentration. Glucagon travels through the bloodstream until it reaches glucagon receptors which are predominantly found in the liver, as well as, the kidneys. Glucagon stimulates the breakdown of stored glycogen to be released into the bloodstream as glucose. It also stimulates the conversion of amino acids into glucose and the breakdown of fat into fatty acids. These effectors cause an increase in blood glucose levels back towards the normal. This increase in blood glucose concentration is detected by the alpha cells which then stop the secretion of
Our body obtains the energy by digesting the carbohydrates into glucose. Volumes of glucose are required by the body to create ATP. ATP is short for 'Adenosine Triphosphate ' and is an energy carrier. When we consume too many carbohydrates our body produces a lot of glucose and as a result blood glucose levels rise and sometimes they may rise over the normal range of blood glucose concentration. To bring it back within the healthy range, the homeostatic system of blood glucose regulation is used. The blood flows through the pancreas where the beta cells, receptors, detect the high blood glucose level. To counteract this stimuli beta cells alert the control centre, which are also the beta cells located in the islets of Langerhans in the pancreas. The secretion of insulin has to be done quickly but can only be carried out when insulin gene is switched on. Turning on the insulin gene switch can take 30 minutes to an hour therefore, the production of insulin by beta cells are done in advance and are packaged in vesicles right until blood glucose rises. Glucose comes into the beta cell to trigger the vesicle that contains the insulin to move towards the plasma membrane and fuse. This releases the insulin into the bloodstream where they are distributed throughout the body and only affect specific target cells. The receptor, a protein, on the target cell’s plasma membrane recognises and connects
The walls of the intestine may contain a mucous membrane (epithelia, lamina propria, and muscularis mucosa), submucosa (muscularis externa, inner circular fibers, outer longitudinal fibers), and serosa (mesothelium, connective tissue) ("Epithelial Cells").
Insulin is a hormone that is produced by specialized cells on the surface of the pancreas called pancreatic islets or Islets of Langerhans. It causes changes to occur in the plasma membrane of the cell that cause the cell to pull in glucose from the blood stream. The hormonal counterpart of insulin is glycogon, which serves to promote the rele...
The pancreas is composed of exocrine and endocrine tissues. The exocrine portion of the pancreas synthesizes and secretes pancreatic juices. The endocrine portion is composed of miniscule islands of cells, called the islets of Langerhans. These islets of Langerhans do not release their secretions into the pancreatic ducts. Instead, they release hormones into the blood stream, and these hormones in turn help control blood glucose levels (Function of the Pancreas). Beta cells of the islets of Langerhans secrete insulin, which
The pancreas can be divided into two sections when studying the histology. The pancreas has exocrine and endocrine functions, each with unique cell types. The exocrine pancreas serves to secrete digestive enzymes into the duodenum. Some of the specific enzymes and secreted substances are Proteases, lipase, amylase, bicarbonate, and water (Bowen, “Exocrine Secretions”). These enzymes are used to break down protein, fat, and carbohydrates respectively. The bicarbonate simply act as an acid buffer to prevent damage of the small intestine as the stomach acid must be neutralized. The enzymes are created in acinar cells and the bicarbonate is synthesized in epithelial cells surrounding pancreatic ducts (Bowen “Exocrine
Pancreas- The pancreas creates a juice that breaks down carbohydrates, fats, and proteins. "The pancreas delivers digestive juice to the small intestine through small tubes called ducts" (NIH (5).) The pancreas is not considered part of the GI tract, but it is a necessary organ needed for the digestion and absorption of nutrients.
The pancreas has two functions; to make enzymes that help digest fats and proteins and the other, to produce insulin that controls the blood sugar level called glucose. It consists of Islet cells (1 of 3 types), which are endocrine glands. This means the Islet cells secret the insulin directly into the blood stream. The pancreas contains many more of these Islet cells than the body needs to maintain a normal insulin level. Even when half of the pancreas is removed, the blood sugar level can still remain normal. The pancreas is also made up of exocrine glands, which produce enzymes for digestion.
Blood glucose levels are the measurement of glucose in an individual’s blood. This is important because glucose is the body’s main source of fuel and the brains only source of fuel. Without energy from glucose the cells would die. Glucose homeostasis is primarily controlled in the liver, muscle, and fat where it stored as glycogen. The pancreas is also a significant organ that deals with glucose. The pancreas helps regulate blood glucose levels. Alpha-islet and beta-islet pancreatic cells measure blood glucose levels and they also regulate hormone release. Alpha cells produce glucagon and beta cells produce insulin. The body releases insulin in response to elevated blood glucose levels to allow the glucose inside of cells and
...hunger as the hormone insulin lets cells to enter glucose in the blood; when the pancreas discharges insulin hunger will rise.
The pancreas uses these two hormones in order to monitor blood glucose levels. After a meal, blood glucose usually rises. This is when insulin secretion will start (Nussey S, Whitehead S. “Endocrinology: An Integrated Approach”). Consequently, blood glucose decrease to the normal range. This is how insulin maintains blood levels when is high. However, when blood level falls below normal range, glucagon comes into play. Low blood glucose occurs usually when hungry and during exercise. This will then triggers glucagon secretion. When blood level falls, the body goes into imbalance. Hence is why in order to maintain homeostasis glucagon is crucial. The body will tell the pancreas to increase more glucose and the pancreas will secrete glucagon by taking glycogen from the liver to produce glucose. The glucose will produce energy and will make blood glucose concentration increase (Homeostasis of Insulin and Glucose, Abpischools.org). When the pancreas cannot maintain homeostasis, many problems will arise in the body. When the pancreas fails to produce insulin, type 1 and 2 diabetes can occur. For those with type 1 diabetes, insulin injections will be needed in order to regulate blood glucose level, otherwise, glucose levels will be out of control. For type 2 diabetes, they are not insulin dependent like type 1, however, the body does not create enough in the body. When blood glucose
Epithelial tissue covers the surface of the human body and lines most internal cavities. Epithelial tissue is found in the body’s skin, lining of the stomach and intestines, the kidney, and glands, as well as other locations within the body (Amsel, 2012). The two types of epithelial tissue are (1) covering and lining epithelium and (2) glandular epithelium. The covering and lining epithelium are found lining the integumentary, digestive, cardiovascular, and respiratory systems as well as the ventral body cavity and the organs this cavity houses (Hoehn, et al., 2007, p. 118). The glandular epithelium is found within the glands of the entire human body. Not only are their two types of epithelial tissue found in the human body, there are also multiple classifications and various shapes. These classific...
The stomach is a muscular pouch located beneath the diaphragm, with the principal function of storing food before it is released into the small intestine (Thompson, 2013). Along with food storage, the stomach is also responsible for beginning the digestion of protein and triglycerides (Tortora & Derrickson, 2009). It is composed of five layers, including the mucosa, submucosa, muscularis, serosa and an extra coat of oblique muscle (Walker, 2014). Within the mucosa layer of the stomach, gastric glands are formed. These glands secrete gastrin, a significant secretion which impacts stomach functions (Walker, 2014). Gastrin stimulates parietal and chief cells, resulting in the secretion of hydrochloric acid (HCl) and pepsinogen. Gastrin also contracts the lower esophageal sphincter, eases the pyloric sphincter and enhances motility within the stomach (Tortora & Derrickson, 2009). The oblique muscle gives the stomach the ability to contract rapidly for the purpose of digesting food (Thompson, 2013). The stomach is responsible for processing food to be further digested, while the abdominal muscles work to process food and mix it with gastric liquid, resulting in the formation of chyme (Thompson, 2013). Chyme is then secreted, conta...