Wait a second!
More handpicked essays just for you.
More handpicked essays just for you.
Effect Of Glucose In The Body
Don’t take our word for it - see why 10 million students trust us with their essay needs.
Homeostasis Homeostasis is the biological process that maintains a stable internal environment despite what occurs in the external environment. Chemicals and bodily functions are maintained in a balanced state so the body may function optimally. There are various systems in the human body that require maintenance through the processes of biochemical checks and balances so they may function properly. One of these systems includes the rise and fall of blood glucose and is under the control of the homeostatic regulation process. Homeostasis is essential in blood glucose regulation as high blood glucose levels (hyperglycaemia) and low blood glucose levels (hypoglycaemia) are dangerous and can affect the human body in many ways and can also lead …show more content…
Our body obtains the energy by digesting the carbohydrates into glucose. Volumes of glucose are required by the body to create ATP. ATP is short for 'Adenosine Triphosphate ' and is an energy carrier. When we consume too many carbohydrates our body produces a lot of glucose and as a result blood glucose levels rise and sometimes they may rise over the normal range of blood glucose concentration. To bring it back within the healthy range, the homeostatic system of blood glucose regulation is used. The blood flows through the pancreas where the beta cells, receptors, detect the high blood glucose level. To counteract this stimuli beta cells alert the control centre, which are also the beta cells located in the islets of Langerhans in the pancreas. The secretion of insulin has to be done quickly but can only be carried out when insulin gene is switched on. Turning on the insulin gene switch can take 30 minutes to an hour therefore, the production of insulin by beta cells are done in advance and are packaged in vesicles right until blood glucose rises. Glucose comes into the beta cell to trigger the vesicle that contains the insulin to move towards the plasma membrane and fuse. This releases the insulin into the bloodstream where they are distributed throughout the body and only affect specific target cells. The receptor, a protein, on the target cell’s plasma membrane recognises and connects …show more content…
The main cause of diabetes is that the insulin produced by the pancreas is not working properly so the body has an abnormally high blood glucose level. There are two important reasons why this happens: either there is no insulin present in the body, Type 1 Diabetes, or there is insulin present but it is unable to work, Type 2 Diabetes. Type 1 Diabetes Mellitus is also referred to as insulin-dependent as the secretion of the hormone insulin by the pancreas is reduced to minor levels due to the destruction of the pancreatic beta cells by immune system of the body. Therefore, Type 1 Diabetes is an autoimmune condition due to the fact that the body is harming the pancreas with antibodies so beta cells cannot make any insulin for bloodstream to take in glucose. The fact that the cells in the body cannot take in glucose means that it builds up in the blood and hyperglycaemia occurs. This abnormally high level of blood glucose is able to harm the nervous system, tiny blood vessels in the kidneys, heart and the eyes. Type 1 Diabetes is fatal when left untreated as it then causes heart disease, kidney disease, damage to the nerves, stroke and
The beta cells affect a person’s glucose regulations within the blood. This is because the beta cells are in charge of sending insulin arou...
According WebMD 2014. Diabetes mellitus (or diabetes) is a chronic, lifelong condition that affects your body's ability to use the energy found in food. There are three major types of diabetes. Type 1 diabetes mellitus, type 2 diabetes mellitus and gestational diabetes. It is a hormonal disorder of the pancreas either decrease in insulin level also known as hypoinsulinism or increase in insulin level also known as hyperinsulinism. Lowered amounts, insufficient of, or ineffective use of insulin leads to the disorder of diabetes mellitus. It is common chronic disease requiring lifelong behavioral and lifestyle changes. According to Peakman (2012). The development of type 1 diabetes mellitus is a genetic and an autoimmune process that results in destruction of the beta cells of the pancreas, leading to absolute insulin deficiency. There is usually a pre-diabetic phase where autoimmunity has already developed but with no clinically apparent insulin dependency. Insulin autoantibodies can be detected in genetically predisposed individuals as early as 6-12 months of age. In persons genetically susceptible to type 1 diabetes, a triggering event, possibly a viral infection the leads to production of autoantibodies that kill the beta cells and results in decline and a lack of insulin secretion. According to Wherrett. It is caused by impaired insulin secretion and insulin resistance and has a gradual onset. Those with type 2 diabetes may eventually need insulin treatment. Gestational diabetes mellitus is glucose intolerance during pregnancy in a woman not previously diagnosed with diabetes, this may occur if placental hormones counteract insulin, causing insulin intolerance. Complications in diabetes mellitus includes: Hypoglycemia it is ca...
This is monitored by the cells within the Islets of Langerhans, which is located in the control (the pancreas). After skipping a meal or tough physical exercise blood glucose concentration decreases. Alpha cells in the islets detect this drop and are stimulated to secrete glucagon. Glucagon is a polypeptide hormone which influences an increase in blood glucose concentration. Glucagon travels through the bloodstream until it reaches glucagon receptors which are predominantly found in the liver, as well as, the kidneys. Glucagon stimulates the breakdown of stored glycogen to be released into the bloodstream as glucose. It also stimulates the conversion of amino acids into glucose and the breakdown of fat into fatty acids. These effectors cause an increase in blood glucose levels back towards the normal. This increase in blood glucose concentration is detected by the alpha cells which then stop the secretion of
Type 1 Diabetes formerly called juvenile onset diabetes occurs typically before the age of 20, but now at any age anyone can be diagnosed with type 1. Individuals with type 1 diabetes are usually thin, go to the bathroom a lot to urinate, and are always hungry. The cause of Type 1 Diabetes is that the pancreas, which is the organ that secretes insulin, is destroyed by auto antibodies, which is why people with Type 1 Diabetes always need insulin, either to be injected or through an insulin pump. When glucose cannot enter the cells, it builds up in the blood causing the body's cells to starve to death. People with type 1 diabetes mus...
Type 1 diabetes has a genetic onset that often occurs in adolescence (Porth, 2005). It is an autoimmune disease in which the insulin-producing beta cells within the liver are destroyed (Dorman, 1993). This causes a deficiency in insulin secretion, which ultimately leads to high blood glucose levels, also referred to as hyperglycemia (Guthrie & Guthrie, 2004). The mechanism for insulin deficiency leading to hyperglycemia is described in more detail in the following section and in Figure 1.
Diabetes is a disease in which a person’s body in unable to make or utilize insulin properly which affects blood sugar levels. Insulin is a hormone that is produced in the pancreas, which helps to regulate glucose (sugar) levels, break down carbohydrates and fats, and is essential to produce the body’s energy. The CDC (2013) offers reliable insight, summarized here, into the different types of diabetes, some causes, and health complications that may arise from the disease.
When the blood glucose is higher than the normal levels, this is known as diabetes disease. The body turns the food we eat into glucose or sugar and use it for energy. The insulin is a hormone created by the pancreas to help the glucose get into the cells. The sugar builds up in the blood because either the body doesn’t make enough insulin or can’t well use its own insulin (CDC, 2015). In the United States diabetes is known as the seventh leading cause of death. There are different types of diabetes. However, there are two main types of diabetes and these are; Diabetes type 1 and Diabetes type 2 (CDC, 2015).
Insulin is released when the β cells of the islets of langerhans in the pancreas detect an increase in blood sugar levels. Insulin’s release is also stimulated by increased levels of amino acids and acetylcholine denoting activation of the parasympathetic nervous system. Both of these things signify digestion, which is usually responsible for increases in blood sugar. In...
The ANS is part of the peripheral nervous system, being split into sympathetic pathways, which prepare the body for action and parasympathetic pathways which prepare the body for rest. This regulates the functions of the body and some of the muscles automatically.
Diabetes is a disease that causes an abnormally high level of sugar, or glucose, to build up in the blood. Glucose comes from food we consume and also from our liver and muscles. Blood delivers glucose to all the cells in the body. In people without diabetes, the pancreas makes a chemical called insulin which is released into the blood stream. Insulin helps the glucose from the food get into cells. When the pancreas doesn’t make insulin, it can’t get into the cells and the insulin stays in the blood stream. The blood glucose level gets very high, causing the person to have type one diabetes.
Homeostasis can be defined as the ability or tendency of an organism to maintain its stability. If an organism does not maintain homeostasis it will die. Dynamic equilibrium is what happens when the organism adjusts to maintain a constantly balanced internal environment. Dynamic equilibrium is caused by the organs inside humans and other animals fluctuating between increasing or decreasing their function to maintain homeostasis. The way these organs react is known as a response, and the response is reacting to a stimulus. A stimulus is something that affects the way organisms function. The body maintains homeostasis by working with the nervous system. The nervous system releases hormones which signal the cells or organs to decrease or increase their function.
Type 1 diabetes, is an incurable but treatable disease which can occur at any age but is mostly found in children due to the high levels of glucose in the blood (Eckman 2011). Juvenile diabetes affects about 1 in every 400-600 children and more than 13,000 are diagnosed yearly (Couch 2008). Type 1 Diabetes means your blood glucose, or blood sugar, is too high. With Type 1 diabetes, your pancreas does not make insulin. Insulin is a hormone, which helps glucose gets into your cells to provide energy. Without insulin, too much glucose stays in your blood. Over time, high blood glucose can lead to serious problems with your heart, eyes, kidneys, nerves, gums and teeth (American Diabetes Association). Previous research has suggested proper insulin management, a balanced diet and exercise will help maintain glycemic control and lessen the chance of complications (Couch 2008).
For people with no problems the intestines and stomach digest the carbohydrates that we take in into glucose, which is the body’s main source of energy. After we digest our food the glucose moves to the bloodstream. To get the glucose out of your blood and into the cells of your body the pancreas makes a hormone called insulin (Mayo Clinic, 2010). When you have gestational diabetes either your body does not make enough insulin during your pregna...
The pancreas uses these two hormones in order to monitor blood glucose levels. After a meal, blood glucose usually rises. This is when insulin secretion will start (Nussey S, Whitehead S. “Endocrinology: An Integrated Approach”). Consequently, blood glucose decrease to the normal range. This is how insulin maintains blood levels when is high. However, when blood level falls below normal range, glucagon comes into play. Low blood glucose occurs usually when hungry and during exercise. This will then triggers glucagon secretion. When blood level falls, the body goes into imbalance. Hence is why in order to maintain homeostasis glucagon is crucial. The body will tell the pancreas to increase more glucose and the pancreas will secrete glucagon by taking glycogen from the liver to produce glucose. The glucose will produce energy and will make blood glucose concentration increase (Homeostasis of Insulin and Glucose, Abpischools.org). When the pancreas cannot maintain homeostasis, many problems will arise in the body. When the pancreas fails to produce insulin, type 1 and 2 diabetes can occur. For those with type 1 diabetes, insulin injections will be needed in order to regulate blood glucose level, otherwise, glucose levels will be out of control. For type 2 diabetes, they are not insulin dependent like type 1, however, the body does not create enough in the body. When blood glucose
Diabetes is a disease that I came across when researching my maternal side of my family history. Diabetes is a disease that affects your pancreas an important organ in regulating blood sugar. When a person has diabetes there are two ways it can affect the pancreas because there are two types of the disease. Type-1 diabetes affects the pancreas by not allowing the body to produce enough insulin to keep the body’s blood sugar at a healthy number. The opposite is for Type-2 which produces too much insulin and gives the body too much insulin keeping the blood sugar number above healthy (Type-2).