Yeast Enumeration Essay

1951 Words4 Pages

Title

Enumeration of yeast from a pure culture or diluted solution by methods of direct count, viable count, and turbidity study.

Abstract

The goal for using all three enumeration techniques is to not only understand direct count, viable count, and turbidity study, it is to also understand the advantages and disadvantages of each so that researchers can use them in the most efficient ways when studying microorganisms. The idea was that if the direct count gives a certain number of microorganisms, then the viable count and turbidity study should also give us similar number outcomes of the same organism, taking into account dilutions. The researchers concluded that this did occur better in some methods of enumeration than others.

Introduction …show more content…

To make sure that an accurate number of colonies will be produced, several dilutions are necessarily cultured. The procedure in the laboratory involves creating serial dilutions of the sample (1:10, 1:100, 1:1000 etc. ) in a sterile water environment and spread onto nutrient agar dishes that are sealed and incubated. What these nutrient plates consist of, depends on the different types of microorganisms being researched and targeted to grow. In most cases, the bacteria being studied can be easily identified from the nutrient plate. If cells are dispersed on the plate properly, it may be assumed that each cell will grow into a single colony that is seen with the naked eye and is not time strenuous at the moment of counting. In the total amount of time, this could take is a couple of weeks and sometimes does not work as planned, where researchers may get more or fewer colonies than expected. The colonies can be counted and are based on the known volumetric amount of the culture that was transferred to the plate and therefore the cell concentration may be calculated. The grand total of microorganisms found on the plate is called the total viable count (TVC) and is measured in the unit of CFU/mL (colony forming units). To calculate the CFU/mL, the counted number of colonies has to be multiplied by the dilution used. Usually the bacterial colony counts are important …show more content…

From the direct count culture, a serial dilution was completed, and this is where the final dilution had the cell quantity in the countable range of 30-300. For viable count, two Petri dishes were labeled, with “A (1 x 10 ^ -5)” and one “B (2 x 10 ^ -5),” To add, the first 99 mL DI H2O bottle was labeled with “1 to 100” ratio and the other bottle was labeled with a “1 to 10,000” ratio. Lastly, the 9 mL DI water tube was labeled with “1 to 100,000” ratio. Researchers added 1 mL of pure yeast culture into a bottle labeled “1:100” and mixed well. After, they took 1 mL from bottle number 1 and put it into bottle number 2, also mixing well with the 99 mL DI H2O. Taking 1 mL of bottle number 2, researchers added this amount to the 9 mL water tube and mixed well. After the dilutions of the yeast culture, the YED medium was ready to be smeared with yeast dilution. Researchers melted the YED agar bottles and kept it in the water bath with the temperature at 58°C to maintain its liquid form. After that, they poured YPD until the dishes were half full, and in the liquid form, swirled in 1 ml from the 9 mL tube onto plate “A” and 2 mL of the tube onto plate “B”. If the medium was too hot, it would kill the microorganisms off and if too cold, it would cause them to clump. The

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