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How did war kinfluence the development of penicillin
The history of penicillin essay
The history of penicillin essay
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If Alexander Fleming didn’t notice that there was something strange with the petri dish that contained Penicillium notatum, then the a big majority of people would not be alive today. Penicillin is antibiotic or group of antibiotics produced from specific blue molds. It can treat certain infections such as ear, throat, and skin infections, it can also be used to treat rheumatic fever and chorea, because of penicillin the death rate of people dying from these bacterial infections has incredibly decreased. Penicillin is one of the most important discoveries of medicine that has made an important impact because of how it changed the course of medicine, how it affected the World War 2, and how it changed the world globally. …show more content…
First, the discovery of penicillin has been named the most important discovery of the millennium, it has created a path for new antibiotics to be discovered and so on and so forth. For example, Theodore C. Eickhoff states “ The discovery of penicillin changed the world of medicine enormously. With its development, infections that were previously severe and often fatal like bacterial endocarditis, bacterial meningitis and pneumococcal pneumonia could be easily treated” (“Accidental Discovery” 2). This quote shows that the discovery of penicillin has definitely made an impact in the medical community by curing infections that could not be curable until the discovery of penicillin. Theodore C. Eickhoff also states that “ This quickly led to a number of pharmaceutical activity, which led to a whole new host of antibiotics, such as streptomycin, aminoglycosides, tetracycline and the like. Penicillin clearly led the way in that development” ( “Accidental Discovery” 3). Penicillin has led to new antibiotics being created which helps cure more bacterial infections and can one day be able to cure most of the bacterial infections we have today. Finally, Theodore C. Eickhoff states “ It is really impossible for me to imaging what the world would be like without penicillin. I question whether there would be a discipline of infectious diseases as we know it today” (“Accidental Discovery” 3). If there was no penicillin then the death toll of people dying from bacterial infections would be incredibly high, and there wouldn’t be as much of a concern for these bacterial infections. Next, during World War 2 penicillin played a vital role in saving the lives of many wounded soldiers, because of penicillin this gave soldiers a second chance to live, while also helping the next generation to come.
World War 2 gave penicillin a chance to show the world that this was indeed a miracle drug by showing its worth, and it proved worthy. For example, “ Penicillin was so effective that production increased from 400 million units in early 1943 to more than 650 billion units per month by the end of the war in 1945” ( “Penicillin: World War 2” 1). Since the production of penicillin increased this showed the effectiveness of penicillin which in returned showed that penicillin could be used worldwide making a global impact. Using penicillin made it uncomplicated for doctors to treat their patients more swiftly. In addition, “ By attacking open wounds with antiseptics, army doctors were able to revitalize troops more quickly” ( “Penicillin: World War 2” 2). Because they were able to revitalize troops more swiftly, the soldiers would be able to get back into combat faster and waste less time than if there was no penicillin. Thanks to penicillin the death rate has incredibly decreased for bacterial infections. Furthermore, “In the war penicillin proved its mettle. “Throughout history, the major killer in wars had been infection rather than battle injuries. In World War 1, the death rate from bacterial pneumonia was 18 percent; in World War II, it fell, to less than 1 percent” ( World First Antibiotic” 2). This quote shows that penicillin is truly effective and that it can be used to assist additional people around the
globe. rial infections and finding ways to manage it as there is today which in return would let to more deaths than there already are.
The Factor of War in the Development of Penicillin The discovery, development and subsequent use of penicillin can be considered to be one of the most important breakthroughs in medical history. There were many factors, which were involved in the development of penicillin, and it could be argued that war was the most important, but other factors were also responsible. Alexander Fleming was working in London as a bacteriologist in 1928 when he noticed that a growth of a mould called penicillin produced a substance that actually killed the germs he was working on. He realised that this might be very important and a year later he wrote an article about his findings. However, Fleming did not have the facilities or the support to develop and test his idea that penicillin could fight infection, and he didn't develop it further.
History has proven the use of chemical weapons ranging back for decades. From the Greeks in ancient Europe using Greek fire to South American tribes using a form of tear gas made of grounded up hot chili peppers to scare away enemy tribes. As well as dipping the tips of spear heads with a poisonous toxin. Poisonous toxins used from live reptiles like frogs and venom from the snakes found from whichever region had enough potency venom to exterminate. The past has proven, that in order for Armies to survive and win, it relied on out smarting the enemy. New technologies and the evolution of weaponry were left to the brightest minds from those eras to develop.
Adegoke AA, Tom M, Okoh AI, Jacob S (2010) Studies on multiple antibiotic resistant bacterial isolated from surgical site infection. Scient Res. Essays 5:3876-81.
Penicillin is an antibiotic that kills bacteria, sufficiently treating any injuries. This drug was invented before the war, but had its major outbreak during World War II. Once scientists discovered the potential of penicillin, they aggressively started to pursue methods to mass produce the drug. The mass production of penicillin saved many American lives and led to our victory during World War II.
Hygiene was extremely poor prior to and during World War 1, especially for soldiers. Because of this and the fact that fighting soldiers couldn’t clean up wounds quickly enough, there were many deaths caused by infection alone. One big issue was trench foot. This was an awful infection caused by soldiers standing in the trenches for too long during battles. Over the course of the war, hygiene and infectious issues were being better dealt with. These issues led to vaccinations and treatment advancements. The earliest forms of the vaccinations and treatments used today were actually introduced in 1914. Those vaccinations and treatments have been improved upon since World War 1. One of the most fascinating things regarding medical procedures at this time has to be blood transfusions. It was 1917, when the first of hundreds of millions of blood transfusions was made. This idea has been improved upon as
Years later other scientists were also intrigued by the possibilities of penicillin and produced enough penicillin to prove that it was a useable antibiotic. The scientists from Great Britain were developing all of this during World War II, and unfortunately funding for their drug was unavailable due to the war. They decided to bring their concepts to the United States, and once enough was made, it was eventually used, to treat wounded soldiers during World War I.
My disease is Streptococcal pneumonia or pneumonia is caused by the pathogen Streptococcus pneumoniae. Streptococcus pneumoniae is present in human’s normal flora, which normally doesn’t cause any problems or diseases. Sometimes though when the numbers get too low it can cause diseases or upper respiratory tract problems or infections (Todar, 2008-2012). Pneumonia caused by this pathogen has four stages. The first one is where the lungs fill with fluid. The second stage causes neutrophils and red blood cells to come to the area which are attracted by the pathogen. The third stage has the neutrophils stuffed into the alveoli in the lungs causing little bacteria to be left over. The fourth stage of this disease the remaining residue in the lungs are take out by the macrophages. Aside from these steps pneumonia follows, if the disease should persist further, it can get into the blood causing a systemic reaction resulting in the whole body being affected (Ballough). Some signs and symptoms of this disease are, “fever, malaise, cough, pleuritic chest pain, purulent or blood-tinged sputum” (Henry, 2013). Streptococcal pneumonia is spread through person-to-person contact through aerosol droplets affecting the respiratory tract causing it to get into the human body (Henry, 2013).
“Legionnaires’ disease is a bacterial infection caused primarily by the species Legionella pneumophila, it was initially recognized as the cause of a 1976 outbreak of respiratory disease outbreak in Philadelphia. Legionellosis infection occurs after persons have breathed mists that come from a water source. The most recent outbreak of Legionnaires’disease is in New York City, in the Bronx, with a total of ten deaths and more than one hundred outbreaks, which were traced to a cooling tower, deaths have also been reported in Michigan, and Ohio.
World War II was the largest war of the twentieth century. No other modern war had as much of an impact on the world as the conflict between the Axis powers and the Allies. Although there were an incredible number of lives lost in World War II, some of that impact caused a change for the better, especially with regards to American culture.
World War One, in its own time, was the most destructive war Earth itself had ever seen, and this was due to the new technology. “There are two groups of people in warfare – those organized to inflict and those organized to repair wounds – and there is little doubt but that in all wars, and in this one in particular, the former have been better prepared for their jobs.” There were many advancements, disadvantages, and foundations involving medicine in World War I. The assassination of Franz Ferdinand on June 28, 1914 started the war, and things spiraled out of control from there. With there being so many existing alliances with countries all over, almost all of Europe became involved. Eventually two sides emerged which were the Central Powers and the Allies. America had tried to stay out of the war, but when Russia backed out in 1917 America slipped in.
18). Even though those diseases were not his goal to cure it still made penicillin revolutionary for the time being. Fleming now knew how to make penicillin and started to mass produce it. In the 1930s during the upgrading process of penicillin Fleming himself was cured of severe conjunctivitis. Then in the 1940s the fully developed penicillin was created. The creation of penicillin cured a wide variety of diseases, which led to the world excelling in growth, and penicillin improved the way of medicine at the time. The variety of diseases cured by penicillin made it a must have antibiotic. Penicillin was used to cure multiple diseases including syphilis, gonorrhea, tuberculosis, gangrene, pneumonia, diphtheria, and scarlet fever ( Common Antibiotics ). All the diseases have one thing in common, they all have the ability to spread, some faster than others. When a disease is discovered people tried to make a cure. When penicillin was made diseases that were thought to never have a cure were cured. People began to demand that penicillin be sold in local pharmacies. Penicillin was released to help people with the variety of diseases curable by
Ernest Chain and Howard Florey with the knowledge of Flemings work were able to successfully purify an extract of penicillin for testing. The tested it in 1940 on mice, they concluded that those who were given the penicillin lived whereas the others did not. Later in 1945 all three men received the Nobel Prize for their contr...
Alexander Fleming started the history of antibiotics in the 1920's with his discovery of penicillin.When penicillin was first discovered and used widely, it was touted as a wonder drug, and consequently was used as one.Though not necessarily harmful to the patient penicillin was used for much more infections than it was able to combat.Today the same practice is observed in the medical profession, however at this point it is due more to the detriment of an uneducated public.Studies have been carried out that show the huge over usage of antibiotics.In the seventies Soyka et al, concluded, "60% of physicians surveyed gave antibiotics for the treatment of the common cold."[3], and by common knowledge the common cold is a virus, something that cannot be treated by an antibiotic.Nyquist
Discovery and Development of Penicillin. (2014, April 4). Retrieved from American Chemical Society International Historic Chemical Landmarks: https://www.acs.org/content/acs/en/education/whatischemistry/landmarks/flemingpenicillin.html
The emergence of Penicillin marked the dawn of the antibiotic era and allowed for diseases which normally ended in death or dysfunction to be eliminated and for people to carry on living healthy lives. It is estimated that 90% of children who had meningitis of the bacterial kind in the pre-antibiotic era would either die or survive the illness with a physical impairment. Strep throat, whooping cough, tuberculosis and pneumonia are among some of the other fatal bacterial diseases which would usually result in a fatality. Antibiotics decreased the mortality rates, and so new antibiotics were formed.