Type 2 Diabetes Essay

NSHIP BETWEEN GUT MICROBIOTA AND TYPE 2 DIABETES
Introduction
Diabetes is a metabolic disease, that causes a person to have high blood pressure. There are two kinds of diabetes, type 1 and type 2. Type 1 is the loss of insulin producing cells, leading to a deficiency of insulin. Type 2 diabetes is where the person is insulin resistant. Insulin is a peptide hormone, which causes cells to absorb the various glucose it requires. Type 2 diabetes is the most widespread endocrine disease worldwide. Metagenome wide associated study took on a study that was based on the determination of type 2 diabetes and relationship to gut microbial by using the deep shot gun sequencing of the gut microbial. The study consisted of 345 Chinese's individuals that were used to help find any relationships. 60000 type 2 diabetes associated markers were used and linked to type 2 diabetes. Gut microbes are living organisms that live in the gut and the digestive tract. Patients with type 2 diabetes were characterized by a moderate degree of gut microbial symbiosis. Symbiosis is a interaction between different microbial organisms, there are various types of symbiosis such as mutalistic, parasitic and communalistic. The abundance of butyrate producing bacteria as well as the opportunistic pathogens were determined as well. Enrichment of microbial functions due to sulphate reduction and oxidative stress resistance was found. Further studies were also performed with addition of individuals to the study. Gut microbial markers may be useful for classifying type 2 diabetes.
Type 2 diabetes has become a major disorder that has affected the world significantly, studies from the genome wide association studies, show that type 2 diabetes may be involved in other geno...

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... a large role and impact significantly on how the body reacts to other organisms and disease. The study was biased as only one ethnical group was tested on the Chinese, perhaps the suggestion of carrying out the same study on other ethnical groups could be explored and studied, by doing this it can be seen if the ethnical group impacts the gut microbes, and if a change in that would cause an effect on type 2 diabetes patients. The study made great use of all the different orthologues, categories and many different data bases, while compiling their own references and taxonomic indexes, while this was great, refereeing to too many data bases may confuse areas that you are looking at examining, it's important to keep on topic and evaluate in appropriately. The study left many others avenues opened and lots more research can be done to further understand their finding.