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Outline the pathophysiology of Type 1 Diabetes Mellitus
Pathophysiology of diabetes essay
Outline the pathophysiology of Type 1 Diabetes Mellitus
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Diabetes mellitus is a disorder of metabolism. It is a chronic disease that occurs either when the pancreas does not produce enough insulin or when the body cannot effectively use the insulin it produces. Diabetes mellitus is a significant public problem that affects about 26 million Americans in the United States has diabetes. Diabetes can go silently undetected for a long time without symptoms. Many people first become aware that they have diabetes when they develop one of its potentially life threatening complications, such as heart disease, blindness or nerve disease. There are 2 main types of diabetes. Type 1 diabetes usually occurs during childhood or adolescence. Type 2 diabetes, which is the most common form the disease, usually occurs in people who are 45 years of age or older. However, the rate of diagnosis of type 2 diabetes in children and adolescents is increasing. Many people who have diabetes, particularly those who use insulin, should have a medical ID with them all the times. In some emergencies, the diabetic person may not always be able to speak or communicate. He or she may even be unresponsive. In these cases, a diabetes bracelet can silently inform the attending medical personnel of the disease. PATHOPHYSIOLOGY OF TYPE 1 AND TYPE 2 DIABETES: The underlying pathophysiologic defect in type 1 diabetes is an autoimmune destruction of pancreatic beta cells. Following this destruction, the individual has an absolute insulin deficiency and no longer produce insulin. Autoimmune beta cell destruction is though to be triggered by environmental event, such as a viral infection. Since the pancreas is no longer produces insulin, people with type 1 diabetes are absolutely dependent on exogenously administered insulin... ... middle of paper ... ...ressure and tendency to retain fluids. Limiting sodium may also help the heart work more efficiently. Exercise is essential for the prevention of diabetes because it helps lower blood sugar levels and also helps the body to use its natural insulin more effectively. Regular blood glucose tests are the only way to know with confidence whether the treatment program is working. Whether type 1 or type 2 diabetes, people who use insulin may need four or more blood glucose checks each day. Each time one performs a blood glucose test, log the results in a record book. The information one record will help to see how food, physical activity, illness and other factors affect blood glucose. Seek support group or consider joining a local diabetes organization is important. One will get a sense of support and discover what others do to cope and lead healthy life with diabetes.
Type 1 diabetes mellitus also known as juvenile diabetes is a serious condition in which the pancreas produces a small amount or no insulin at all. Insulin is a hormone the body needs to transfer sugar into cells to create energy. This disease is most common in children, but can occur in adults around their late 30’s to early 40’s. Unlike patients with type 2 diabetes, type 1 diabetes patients are not usually overweight.
Diabetes Mellitus is defined as “a disease in which too little or no insulin is produced or insulin is produced but cannot be used normally resulting in high levels of sugar in the blood” (merriam-webster.com, 2016). Insulin is a hormone which regulates glucose, or blood sugar, ensuring that it is used as energy by the body’s cells. If the insulin levels are irregular, the glucose remains in the blood
Type 1 diabetes develops when the beta-cells are killed off by the immune system. This is because an inflammation is caused which the immune system fights off, ultimately destroying all/majority of beta cells. The role of the beta cells is to produce insulin within the pancreas. The beta cells are signalled when to release insulin’s to certain parts of the body. A person with type 1 diabetes is likely to have lost 70-80%1 of their beta-cells mass which is why they must manually inject insulin into themselves to maintain a healthy blood glucose level. When the blood glucose level falls (hypoglycaemia) you begin to lose energy.
Type I Diabetes are often found or developed in children and young adults. It was previously called “juvenile diabetes”. Type II diabetes are found in adults and can be seen at any age. This is non insulin dependent diabetes.
Type 1 Diabetes Mellitus is also referred to as insulin-dependent as the secretion of the hormone insulin by the pancreas is reduced to minor levels due to the destruction of the pancreatic beta cells by immune system of the body. Therefore, Type 1 Diabetes is an autoimmune condition due to the fact that the body is harming the pancreas with antibodies so beta cells cannot make any insulin for bloodstream to take in glucose. The fact that the cells in the body cannot take in glucose means that it builds up in the blood and hyperglycaemia occurs. This abnormally high level of blood glucose is able to harm the nervous system, tiny blood vessels in the kidneys, heart and the eyes. Type 1 Diabetes is fatal when left untreated as it then causes heart disease, kidney disease, damage to the nerves, stroke and
However, in the US, the risk of development is higher among African and Hispanic children. Within this, 50% of the children will develop diabetes. When looking at Type I, the typical onset of age for this is usually around 4 to 6 years old and again around 10 to 14 years of age. When looking at incidence, Type I diabetes in 20 year olds has increases by 23% between the years 2003 and 2009. . (Wong, Hockenberry, Wilson, 2015)
Although diabetes can be genetic, that doesn’t necessarily mean you’re prone to get it. Controlling and checking your blood sugar helps to treat diabetes, as well as insulin therapy, regular check-ups/monitoring, and exercising. If you’re diabetic, you’ll find that at first, it’s frustrating and time consuming to treat for your diabetes. You’ll get the hang of it soon enough.
Diabetes type 1 occur when the immune system destroys the beta cells, they are responsible to create insulin and are located
Diabetes is becoming an epidemic. In fact, in 10 years many experts believe that people who suffer from diabetic is going to double. Kids who are as young as 8 years old are now borderline type 2 diabetics.
Type 1 diabetes will be the first case that we will discuss. People get type 1 diabetes from the body not producing enough insulin. Inside your body your immune system sees insulin as being foreign so at that point it begins attack it (University Of Miami). Most people who get type 1 diabetes get it before they turn 40 years old (Medical News Today). Type 1 diabetes is not as common as the type 2 and only 10% of people who have diabetes have type 1.
There are 18.8 million people diagnosed, 7 million people undiagnosed, and approximately 79 million that are pre-diabetic. The ratio of diabetes in children and adolescents, under the age of 20, is about 1 in every 400 children who have diabetes (Statistics, 1). Type 1 diabetes can account for five to ten percent of diagnosed cases of diabetes, although it is the leading cause of diabetes in children of all ages. Usually Type 1 diabetes affects children under the age of ten years old (Overview, 1). Each year, more than 13,000 young people are diagnosed with type 1 diabetes....
Diabetes is a lifelong disease that can affect both children and adults. This disease is the sixth leading cause of death in the United States. It claims about 178,000 lives each year. Type one diabetes, also known as insulin dependent diabetes mellitus, usually occurs in people less than thirty years of age, but it also may appear at any age. Diabetes is a very serious disease with many life threatening consequences, but if it is taken care of properly, diabetics can live a normal life.
Treatments for Type-1 diabetes are taking insulin to help increase your glucose levels (blood sugar), eating healthy, maintaining healthy weight, and monitoring daily your levels. Type-2 treatments include mos...
Diabetes mellitus is a group of metabolic disorders which is characterized by hyperglycemia due to insulin deficiency or resistance or both reasons. (1) According to that diabetes mellitus can be divided as type I and type II. This is common and its incidence is rising, 171 million people had diabetes in 2000 it is expected this condition to be doubled in 2030. It is spread in all the countries and therefore has become a major burden upon healthcare facilities. (2)
Diabetes mellitus (or diabetes) is a chronic, lifelong condition that affects your body's ability to use the energy in food. This means that a person has too much glucose in the blood. There are three major types of diabetes, type 1 diabetes, type 2 diabetes, and gestational diabetes. All types of diabetes mellitus have something in common. Normally, your body breaks down the sugars and carbohydrates you eat into a special sugar called glucose. Glucose fuels the cells in your body. But the cells need insulin, a hormone, in your bloodstream in order to take in the glucose and use it for energy. Insulin is produced in the pancrea...