Temporomandibular disorders (TMD) are a group of clinical conditions that commonly present with the following symptoms: pain in or about jaw joint, with, or without the relating masticatory muscle pain; and/or limited jaw movements with, or without the accompanying joint sounds. Literature review has revealed that TMD is the most prevalent chronic pain condition in the orofacial region, with estimated 5% to 10% of the general population seeking orofacial pain relief. Given TMD can negatively impact one’s work, family life, and social engagement, as well as nutritional deficiencies secondary to the compromised masticatory function, understanding of its etiology and pathophysiology is paramount in formulating effective pain management and functional …show more content…
The precise interrelationship between muscle pain and motor function has been the topic of much debate, with two major, but conflicting theories emerging over the years: the Vicious Cycle Theory and the Pain Adaptation Model.
The Vicious Cycle Theory proposes that orofacial pain is initiated, and sustained by factors such as structural abnormality, eccentric movement, postural changes, and stress, which provoke local inflammatory responses and subsequent peripheral nervous system sensitisation, resulting in muscle spasm or fatigue that perpetuates pain and dysfunction cycle.
The Pain Adaptation Model proposes that the pathophysiology of orofacial pain is more than local inflammatory responses and peripheral nervous system sensitisation, rather, it is the result of a complex interaction between the peripheral and central nervous systems, resulting in muscle activity adjustments that limit movement and thereby protecting orofacial skeletomotor system from further harm and promote healing.
Neither theories, however, can adequately explain orofacial pain in its
It has been shown that intrathecal administriton of GABA receptor antagonists cause hyperalgesia and allodynia. Constitutive, the increase in the endogenous GABA activity in the spinal cord alleviate pain resulting from noxious and innoxious mechanical and thermal stimuli. Different GABA receptors have different roles in alleviating thermal and mechanical pain in different animal pain models. There is no study to date that has examined the involvement of GABA A and GABA B in sensory dimension of neuropathic pain resulting from compression of spinal cord. The current study tests the hypothesis that GABA A or GABA B receptors contributes to the allodynia and hyperalgesia observed after spinal cord injury. The results showed that the effect of GABA A and GABA B receptors on mechanical hyperalgesia is similar but these receptors have different effects on thermal hyperalgesia. While using baclofen as GABA B receptor agonist does not affect the thermal pain, thermal hyperalgesia resulting from spinal cord injury was greatly alleviated by different doses of GABA A agonist, muscimol. Both Baclofen and muscimol are able to reduce the mechanical and cold allodynia has been seen after spinal cord injury but the effect of baclofen is dose dependent with no effect in higher doses used in this study. While almost all doses of muscimol were used in this study reduce the amount of cold and mechanical allodynia. The other result obtained in this study is the short term effect of GABA agonist. The anitinociceptive effect of Baclofen and muscimol appear to be maxium at 15 min after injection and gradually diminished by time and their analgesic effect disappeared 3 hours after injection.
A. Chronic pain signifies a developing public health issue of huge magnitudes, mainly in view of aging populations in developed countries (Russo).
associations, canadian dental assistants. "pain associated with the work of dental assistants causes and solutions." (2008).
Have you ever wondered why when you stub your toe on the chair in the living room, it helps tremendously to yell out an expletive or two and vigorously rub the area? I may not be able to discuss the basis for such language in this paper, but we will explore the analgesic response to rubbing that toe, in addition to the mechanism of pain and alternative treatments such as acupuncture and transcutaneous electrical nerve stimulation.
through the Eyes of a Participant Observer." Chiropractic & Manual Therapies. Vol. 20, No. 1, 19 Jan. 2012, p. 1. EBSCOhost. 2017 October 25.
Introduction: This report is to discuss an experiment to assess the sensory and motor functions of the facial nerve in humans. The facial nerve is one of twelve cranial nerves that innervates the head and neck. These nerves serve a variety of functions, both sensory and motor, and are responsible for moving the muscles in the face, head and neck, and receiving information the brain can interpret into all five sense. Appendix A outlines each cranial nerve, it’s sensory and/or motor function, and the foramen in the bones of the skull it passes through.
The cause of Fibromyalgia is still unknown, but researchers believe it is linked to a disorder of central processing neurotransmitters. They believe the pain is caused by the amplification of abnormal sensory processing in the nervous system. Some studies suggest that genes are involved, but ...
Controlled increases in physical stress through progressive resistive exercise cause muscle fibers to hypertrophy and become capable of generating greater force.3 Early emphasis is on restoring joint range of motion and muscle flexibility, however, resistive exercises are not delayed. The initial emphasis of muscle loading should be on endurance, accomplished with lower loads and higher repetitions. Progressive resistive exercises are initiated at the available range and progressed to new positions as wrist range of motion returns in all planes. Both the overload principle and the SAID Principle (Specific Adaptation to Imposed Demands) are important considerations in therapeutic exercise dosing.1,3,11 Within pain tolerance, dosing progressive resistive exercises that maintain a therapeutic stress level will encourage muscle tissue hypertrophy. Finding activities that produce the correct force and repetition, without injury, is the goal of the remobilization period. Starting with low force, moderate to high repetitions, and encouraging therapeutic rest following induced stress is important to both the overload principle and the SAID Principle. Additionally, it is important to prevent dosing resistive exercises that exceed optimal stress, which may result in injury. The patient’s response to therapeutic exercise should be assessed during, immediately following,
Patients feel fear not so much from the actual pain but from the lack of control that they feel lying in a dental chair. That creates a lot of anxiousness in some patients, as they don’t feel helpless. Most dentists continue treating all patients in a similarly assuming that they all have similar pain level and will handle the procedure in the same way. Dentists should be mindful of their patient’s level of tolerance and make them aware of the entire procedure ahead of time so that they are able to handle the unexpected situations. They should take time to ensure that the patient feels comfortable at every step. Use of medications and wide array of techniques can help patients eliminate pain and anxiety and making dental visits a pleasant experi...
14- Dutt. P, Chaudhary SR, et al. Oral health and menopause: a comprehensive review on current knowledge and associated dental management. Annals of Medical and Health Sciences Research (2013); 3(3): 320-323.
The contraction of a muscle is a complex process, requiring several molecules including ATP and Cl-, and certain regulatory mechanisms [1]. Myosin is motor protein that converts chemical bond energy from ATP into mechanical energy of motion [1]. Muscle contraction is also regulated by the amount of action potentials that the muscle receives [2]. A greater number of actions potentials are required to elicit more muscles fibers to contract thus increasing the contraction strength [2]. Studied indicate that the larger motor units, which were recruited at higher threshold forces, tended to have shorter contraction times than the smaller units [3]. The aims of the experiment were to reinforce the concept that many chemicals are required for skeletal muscle contraction to occur by using the rabbit muscle (Lepus curpaeums) [2]. In addition, the experiment was an opportunity to measure the strength of contraction and to observe the number of motor units that need to be recruited to maintain a constant force as the muscles begin to fatigue [2]. Hypothetically, the rabbit muscle fiber should contract most with ATP and salt solution; and the amount of motor units involved would increase with a decreasing level of force applied until fatigue stage is reached.
There is suggested evidence that a number of anatomical structures such as, bones, intervertebral discs, muscles, ligaments, joints and neural structures cause back pain (Hoy, Brooks, Blyth & Buchbinder, 2010). Degenerative Disc Disease (DDD) is a condition that is believed to cause chronic back pain (Weiner & Nordin, 2010). It occurs when there is an extrusion of disc material into the surrounding tissue (Weiner & Nordin, 2010). It is also suggested that abnormal stress of the ligaments, muscles and mechanoreceptors contribute to back pain (Weiner & Nordin, 2010). The main cause of chronic back pain has not been identified, but there are many suggested issues that are believed to contribute to chronic back pain.
Dentinal hypersensitivity is characterized by a short, sharp pain in response to stimuli. Dentinal hypersensitivity, which is more commonly seen in adults in the 20 – 40 – year old age group, has several etiological factors. Gingival recession and enamel loss both contribute to the prevalence of this condition, resulting in the exposure of dentin.
The muscles responsible for moving your jaw can handle a lot of chewing and talking, but overuse can lead to tightness and pain. Opening