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What is muscle contraction summary
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Skeleton Muscle Lab
Introduction:
The contraction of a muscle is a complex process, requiring several molecules including ATP and Cl-, and certain regulatory mechanisms [1]. Myosin is motor protein that converts chemical bond energy from ATP into mechanical energy of motion [1]. Muscle contraction is also regulated by the amount of action potentials that the muscle receives [2]. A greater number of actions potentials are required to elicit more muscles fibers to contract thus increasing the contraction strength [2]. Studied indicate that the larger motor units, which were recruited at higher threshold forces, tended to have shorter contraction times than the smaller units [3]. The aims of the experiment were to reinforce the concept that many chemicals are required for skeletal muscle contraction to occur by using the rabbit muscle (Lepus curpaeums) [2]. In addition, the experiment was an opportunity to measure the strength of contraction and to observe the number of motor units that need to be recruited to maintain a constant force as the muscles begin to fatigue [2]. Hypothetically, the rabbit muscle fiber should contract most with ATP and salt solution; and the amount of motor units involved would increase with a decreasing level of force applied until fatigue stage is reached.
Materials and Methods:
The experiment that tested the contractile level of muscle in various solutions used a muscle fiber from rabbit’s muscle. One fiber was detached, put under microscope, and submerged first under ATP and salt solution (KCl and MgCl2), then ATP only solution, and lastly salt only solution [2]. The fiber’s level of contraction was measured in micrometers. Muscle contractile strength and number motor units employed at various force lev...
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...gth of contraction: The muscle can be fine or coarse depending on the amount of motor units connected to muscle fibers. For example, the fine muscles contract faster because of higher number of motor units. The length of muscle in terms of its sarcomeres has an effect on the contraction length. The actions potentials have to get farther along and reach more sarcomeres to have them contract (Q3) [1], [2].
Referenced:
[1] Freeman, S. 2013 Biological Science, 5th ed. Pp 973-976
[2] Zelick, R. 2014. Muscle Lab Exercise. Bi253 Lab Manual. Portland State University, OR, pp. 1-5
[3] H. S. Milner-Brown, R. B. Stein, and R. Yemm. "The Orderly Recruitment of Human Motor Units during Voluntary Isometric Contractions." The Physiological Society 230th ser. (1973): 359-70. Web. 22 May 2014.
[4] Nicholas, M. 2014 .Muscle Lab PowerPoint. Bi253 Lab. Portland State University, OR
In the beginning phases of muscle contraction, a “cocked” motor neuron in the spinal cord is activated to form a neuromuscular junction with each muscle fiber when it begins branching out to each cell. An action potential is passed down the nerve, releasing calcium, which simultaneously stimulates the release of acetylcholine onto the sarcolemma. As long as calcium and ATP are present, the contraction will continue. Acetylcholine then initiates the resting potential’s change under the motor end plate, stimulates the action potential, and passes along both directions on the surface of the muscle fiber. Sodium ions rush into the cell through the open channels to depolarize the sarcolemma. The depolarization spreads. The potassium channels open while the sodium channels close off, which repolarizes the entire cell. The action potential is dispersed throughout the cell through the transverse tubule, causing the sarcoplasmic reticulum to release
Parameters of CAL 1 were changed to zero grams and CAL 2 was changed to fifty grams. Nerve stimulation was induced for every fifteen seconds at an increment frequency of 0.5 pps (parts per second), 1.0 pps, 2.0 pps, 4.0 pps, 8.0 pps, 15 pps, and 25 pps. Every increment trial has a thirty-second waiting period. To witness the effects of tubocurare on muscle activity, the baseline was maintained between 20-30 grams and a control was established by turning the stimulator on repeat for 60-120 seconds. Then 0.25 ml of tubocurare was infused into the gastrocnemius muscle.
The data collected during this experiment has shown that a relationship likely exists between the rate of muscle fatigue and the time spent performing vigorous exercise prior to the set of repetitive movements. This is likely due to a build-up of lactic acid and lactate as a result of anaerobic respiration occurring to provide energy for the muscle cell’s movement. As the pH of the cell would have been lowered, the enzymes necessary in the reactions would likely not be working in their optimum pH range, slowing the respiration reactions and providing an explanation to why the average number of repetitions decreased as the prior amount of exercise increased.
The production of physical movement in humans requires a close interaction between the central nervous system (CNS) and the skeletal muscles. Understanding the interaction behind the mechanisms of these two forces, and how they are activated to provide the smooth coordinated movements (such as walking or picking up a pencil) of everyday life is essential to the study of motor control. Skeletal muscles require the activation of compartmental motor units that generate their own action potentials, and produce a voltage force within the muscle fibers that can be detected and recorded with the use of a electromyography (EMG). Therefore, the purpose of this lab was to determine the differences between the timing of force production
Every day we use our skeletal muscle to do simple task and without skeletal muscles, we will not be able to do anything. Szent-Gyorgyi (2011) muscle tissue contraction in rabbit’s muscles and discovered that ATP is a source for muscle contraction and not ADP. He proposed a mechanism to cellular respiration and was later used by Sir Hans Krebs to investigate the steps to glucose catabolism to make ATP. In this paper, I will be discussing the structure of muscle fibers and skeletal muscles, muscle contraction, biomechanics, and how glucose and fat are metabolized in the skeletal muscles.
Kinesiology: The Mechanics & Pathomechanics of Human Movement (Second ed.). Glenside, Pennsylvania: Lippincott Williams & Wilkins. Qiao T, Liu C and Ran F. (2005) The impact of gastrocnemius muscle cell changes in chronic venous insufficiency. Eur J Vasc Endovase Surg 30; 430-436.
Muscle activity, including generating force and moving limbs through lengthening and shortening, is an important influence on beneficial tissue stress. Muscles adapt quickly to periods of lower or higher stress and demonstrate obvious visual and functional changes. At a tissue level, the Physical Stress Theory (PST) states that muscle adaptations are consistent with other high and low strain tissue adaptation models. Low stress/activity associated with immobilization results in decreases in contractile protein, fiber diameter, peak tension and power. Evidence supports the idea that tissues within the musculoskeletal system atrophy and become less tolerant of physical stress if stress on the tissue diminishes below a baseline level.3 In addition,
It is estimated that 1 out of every 5,600-7,700 boys ages 5-24 have Duchene or Becker muscular dystrophy. (“Data & Statistics,” 2012 April 6) Muscular dystrophy is a group of genetic diseases defined by muscle fibers that are unusually susceptible to damage. There are several different types of muscular dystrophy some of which shorten the affected person’s lifespan. (“Muscular dystrophy: Types and Causes of each form,” n.d.) There is a long history of the disorder but until recently there wasn’t much knowledge of the cause. (“Muscular Dystrophy: Hope through Research,” 16 April 2014) Symptoms are obvious and can be seen as soon as a child starts walking. (“Muscular Dystrophy,” 2012 January 19) Although muscular dystrophy mostly affects boys, girls can get it too. (“Muscular Dystrophy,” 2012 January 19) There is no cure for muscular dystrophy but there are several types of therapy and most types of muscular dystrophy are still fatal. (“Muscular Dystrophy: Hope through Research,” 16 April 2014)
Musculoskeletal system provides the ability for movement. Therefore, the musculoskeletal system is composed of multiple different muscles that have a certain way of working. Anyhow, the workings of the muscles have different stages that every muscle must go through to complete a certain task. As a matter of fact, all muscles have the ability to contract and exert a pulling force. For this reason, the muscle contractions are part of every person’s movement of a certain body part. Because of this, the muscle contractions are formed fibers packed within each other to form a rod like myofibrils that contain two types of protein filaments. Also, both of these protein filaments (myosin and actin) help contract the muscle fibers. In consideration of this, when the muscle receives nerve impulses, the protein filaments contract thus making the muscle contract within the body. Furthmore, muscle mechanics play a part in this system. Hence, the mechanics are organized in specific ways that make the tendons attach muscles to bones. In like manner, tendons are compacted tough cords that connect the muscle to bone. They operate as lever systems to move a certain body part. In addition, the muscles work as opponents with opposing result to generate a wide range of controlled movements.
Thibodeau, G., & Patton, K. (1993). Chapter ten: Anatomy of the muscular system. In Anatomy and physiology (1st ed., p. 252). St Louis: MO: Mosby.
The sarcomere is found in structures called myofibrils which make up skeletal muscle fibres. Within the sarcomere there are various different proteins. One of the most significant, myosin is found in the thick filaments of the sarcomere. Although both cells contain myosin, it is important to highlight that smooth muscle cells contain a much lower percentage of myosin compared to skeletal muscle cells. Despite this, myosin filaments in smooth muscle cells bind to actin filaments in a manner similar to that in skeletal muscle cells; although there are some differences. For instance, myosin filaments in smooth muscle cells are saturated with myosin heads so that myosin can glide over bound actin filaments over longer distances, enabling smooth muscle cells to stretch further, whilst in skeleta...
There are quantitative differences in the skeletal muscle action potentials and its duration potentials that is up to five times longer than the duration of myelinated nerve fibers. Significantly lower than the velocity of conduction in the nerve fibers that innervate muscle fibers is the velocity of conduction in skeletal muscle fibers. The stretching of the tendon attached to the muscle activates specialized receptors in the muscle that send signals to motorneurons through one synapse. The impulse from the motorneuron causes the muscle fibers to depolarize and
in soft tissue mobilization pressure.” Medicine and Science in Sports and Exercise. April 1999: 531-5.
Cardiac muscle is a type of involuntary muscle found only in the walls of the heart, specifically the myocardium. Cardiac muscles contract automatically to tighten the walls of the heart in a rhythmic fashion (pp.212-216). The heart beats nonstop about 100,000 times each day (p.18). Smooth muscle is a type of involuntary muscle found within the walls of blood vessels such as in small arteries and veins. Smooth muscle is also found in the urinary bladder, uterus, male and female reproductive tracts, gastrointestinal tract, and the respiratory tract. Skeletal muscles are voluntarily controlled and are attached to bones by tendons. Skeletal muscles also vary considerably in size and shape. They range from extremely tiny strands such as in the muscle of the middle ear as large like in the muscles of the thigh (Martini, 2000). The three individual muscle types also serve five main functions. The five basic functions are movement, organ protection, pumping blood, aiding digestion, and ensuring blood flow.
The muscular system is a very important part of the human body. It has many components and functions, and is the source of the body’s movement. There are roughly 650 muscles in the human body and are different types of muscles. Muscles can either be voluntary or involuntary which means controlled or uncontrolled movement. Muscles have many reasons and in this paper you will widen your knowledge of muscles and their functions as well their diseases and how they help maintain the body.