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Essays on complexities of pain and pathways
Pain pathophysiology
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"Oww! &%$%!" Pathways of Pain and Alternative Methods of Pain Relief Have you ever wondered why when you stub your toe on the chair in the living room, it helps tremendously to yell out an expletive or two and vigorously rub the area? I may not be able to discuss the basis for such language in this paper, but we will explore the analgesic response to rubbing that toe, in addition to the mechanism of pain and alternative treatments such as acupuncture and transcutaneous electrical nerve stimulation. In the two previous papers for this class I have chosen to focus upon the inherent power of the brain in relation to healing. Studies of the placebo effect and psychoneuroimmunology have helped us gain insight into the nervous system's relationship with the immune system, the endocrine system, and others. Alternative therapies such as hypnosis, relaxation/ meditation, and humor have been discussed in association with this relationship. I feel that my exploration of the brain and alternative healing would not be complete without an investigation of the processing of pain and the role of acupuncture and touch in pain relief. What exactly is pain? According to Webster's dictionary, pain is "physical suffering typically from injury or illness; a distressing sensation in a part of the body; severe mental or emotional distress". Most everyone reading this paper has experienced some form of physical pain at some point during their lives; most everyone has even experienced the common daily pains such as stubbing our toe as we walk through the living room, accidentally biting our tongue as we chew, and having the afternoon headache after a long day of work. No matter the fact that it is unpleasant, pain has a very important role in telling the body that something is not right and leading to behavior that will remove the body from a source of potential injury. Imagine if we could not experience pain. We would not be able to change our behavior in any way when touching the burning hot dish in the oven, resulting in potentially serious burns. We could not recognize that perhaps we twisted an ankle when walking down the stairs, thus continued walking on that foot would exacerbate the injury to the point of not being able to walk at all. Indeed, pain is not pleasant, but in many cases it is an important way for our nervous system to learn from and react to the environment.
Ross defines and differentiates between the terms healing and curing. She recognizes the fact that healing and curing are very intertwined and it can be hard to distinguish between the two terms. There are differences between the definitions in scholarly and general settings. She references an ethnographic study of healing versus curing conducted by anthropologists Andrew Strathern and Pamela Stewart in 1999 with native groups in New Guinea. The results of the study looked at how energy used by the different types of tribal healers to either cure or heal a patient. Eastern medicine focuses on how energy interacts with the healing process in connection within the mind. Whereas Western medicine is focused on the mind and the body separately. The practice is considered a holistic approach to finding cures. According to Ross (2013), healing is more a therapeutic process targeting the whole body and specific illness including emotional, mental, and social aspects in the treatment. The act of curing is a pragmatic approach that focuses on removing the problem all together. The life experiences of a person playing into how well certain treatments will heal or cure what is ailing them. These aspects can not be defined with textbook definitions. The interaction that the healing process has with energy is a variable in the success rate. Uncontrolled emotions can have a greater impact on the inside the body than a person can realize. The exploration of energy interaction within the body can be used for greater analysis of health care systems. (21-22). Are Western healthcare facilities purposely “curing” patients just so that they return are few years later? Is Western Medicine built upon a negative feedback loop? The terminolo...
No obvious boundaries are observed between the two distinct materials, tendon and bone. Type I collagen and tenocytes are highly aligned in tendon. In uncalcified fibrocartilage, where collagen type II is of great content, along with rich type III collagen and small amount of type X collagen, decorin, and aggrecan. Similarly, with a great amount of type II collagen, the mineralized cartilage presents significant amounts of collagen type X and scarce levels of aggrecan. Note that the collagen fibers are highly aligned in the direction of tensile force in tendon but less oriented in the insertion site (Figure 2).[4, 19] Additionally, the insertion site possesses a transitional decrease in tissue organization while an increase in mineral content.[4] The complex collagen and mineralization content in this region lead the repair and rehabilitation of tendon-to-bone insertion site more
It has been shown that intrathecal administriton of GABA receptor antagonists cause hyperalgesia and allodynia. Constitutive, the increase in the endogenous GABA activity in the spinal cord alleviate pain resulting from noxious and innoxious mechanical and thermal stimuli. Different GABA receptors have different roles in alleviating thermal and mechanical pain in different animal pain models. There is no study to date that has examined the involvement of GABA A and GABA B in sensory dimension of neuropathic pain resulting from compression of spinal cord. The current study tests the hypothesis that GABA A or GABA B receptors contributes to the allodynia and hyperalgesia observed after spinal cord injury. The results showed that the effect of GABA A and GABA B receptors on mechanical hyperalgesia is similar but these receptors have different effects on thermal hyperalgesia. While using baclofen as GABA B receptor agonist does not affect the thermal pain, thermal hyperalgesia resulting from spinal cord injury was greatly alleviated by different doses of GABA A agonist, muscimol. Both Baclofen and muscimol are able to reduce the mechanical and cold allodynia has been seen after spinal cord injury but the effect of baclofen is dose dependent with no effect in higher doses used in this study. While almost all doses of muscimol were used in this study reduce the amount of cold and mechanical allodynia. The other result obtained in this study is the short term effect of GABA agonist. The anitinociceptive effect of Baclofen and muscimol appear to be maxium at 15 min after injection and gradually diminished by time and their analgesic effect disappeared 3 hours after injection.
Pain is something that several Americans suffer from on a daily basis for varying reasons.
create a perfect society by eradicating individuals it deemed contrary to the model Aryan race. The result was Nazi control of the lives of individual citizens across Europe and systematic murder of more than six million people who either spoke out against the regime or were considered unworthy of life within the corrupt insitution of Nazism. How did so few within the corrupt Nazi regime control the life and death of millions of individuals?
Cartilage serves as protection against bone on bone contact to prevent wear in bones an example of this is the lateral and medial meniscal cartilage (articular cartilage). But the lateral and medial meniscal cartilage can be quite easily torn although a common injury in fully grown adults torn cartilage cannot be healed as cartilage receives little blood flow making it hard for it to heal compared to children with
Human rights have been a longstanding and important issue that the UN has been addressing since its inception. One particular country of unrest is Serbia, where history has led to some unpleasant political situations and, as a result, severe human rights issue have arisen. Serbia – landlocked between Bosnia and Herzegovina on the West and Romania on the East – is a historically complex and very new country. Serbia only became separate from Moldova and Kosovo as recently as 2006 and 2008 respectively. Constant political distress has proven difficult to maintain an appropriate human rights code without high degrees of exploitation, especially during the breakup of Yugoslavia. It is the various human rights issues in Serbia that will be examined in this paper, looking to the UN for support and to head in the right direction.
Marion Good, PhD, RN, has focused her study, “A Middle-Range Theory of Acute pain Management: Use in Research,” on complementary medicine for pain and stress, acute pain, and stress immunity. The purpose of this theory is to put into practice guidelines for pain management. Good, 1998, noted the need for a balance between medication usage and side effects of pain medications. The theory also promoted patient education related to pain management following surgery and encouraged plan development for acceptable levels of pain management. This theory was developed through deductive reasoning. Chinn & Kramer, 2008, defined deductive reasoning as going from a general concept to a more specific concept. Good, 1998, related that there was a balance between analgesia and side effects in which two outcomes can be deduced: (1) a decrease in pain, and (2) a decrease in side effects. These outcomes can be studied further or more detailed concepts can be deduced from them.
Traditional African medicines, and the spiritual healers that administer these medicines are an important part of African society. For many centuries and even millenniums these healers with there spiritual and naturalistic remedies have been responsible for taking care of the African world as we know it. Traditional African medicines have been a greater help to all of society and modern science, but still lie at the root of much controversy over its ability to be a valid healing tool. Some doctor’s and scientist believe that a possible placebo effect may be the root of what makes these remedies and rituals work; but there is also evidence that suggest that many of the ingredients found in our medicines today are also found in the natural animal and plant products used by the healers. In fact many pharmaceutical companies have recently been looking at the content of these natural substances in hope of finding chemical compounds that can help modern science in producing modern medicines to cure disease. Despite modern day societies use of the healers remedies in modern medicine, there still seems to be some confusion as to who the healer really is and what their motives are. Many people using naïve thought process perceive the healer as one practicing witchcraft. This may be due to the disbelief that natural substances are capable of healing, or the belief that ritualistic and spiritualistic ceremonies and practices stem from evil or voodoo. Despite all of this opposition and change into a more scientific world, the healer remains as one of the most sought after people in the African world, and even in large African cities were western heal...
The cartilage is the smooth layer which covers the ends of the bones and which stops the bones rubbing together. It has high tensile strength, but it is not rigid. Can compressed and is able to act as a shock absorber.
...ory rights; that have to be followed by all nations or all people, it has been widely accepted. It is important to note that opinions and views on international human rights do indeed vary; there are people for it as well as people against it. The United Nations has openly embraced international human rights and is a primary promoter and source for it. Along with the prominence of international human rights, it has had both positive and negative impacts. A positive impact being that it has motivated organizations to help those in need of rights, such as a right to shelter. While a negative impact has been it has caused a sense of division, between nations because people's views on human rights do differ. Internationally human rights have been a relevant topic of discussion throughout history, at this present time, and will most likely continue to be in the future.
Treaties are the highest source of international law besides jus cogens norms that have binding effect on the parties that ratify them.2 International human rights treaties rely on the “name and shame” mechanisms to pressure states to improve practices.3 However with “toothless” international human rights norms, moral coercion is not always effective. An empirical study conducted by Professor Oona Hathaway assessing the effect of human rights treaty ratification on human rights compliance, maintains in its findings that ratification of human rights treaties has little effect on state practices.4 States do not feel pressured to comply and change their practices, rather, signing treaties is “more likely to offset the pressure rather than augment it.”5 So, is it time to abandon human rights treaties and remit protection of human right to domestic institutions. Hathaway posits elsewhere that despite this treaties “remain an indispensable tool for the promotion of human rights.”6 Instead of getting rid of the treaty system, it is necessary to enhance the monitoring and enforcements mechanism to strengthen the human rights regime to ensure compliance.7 This article evaluates the extent to which international law serves as a useful tool for protection of human rights.
Figure 4.3 depicts the ossification and calcification activity of the nasal cartilage. It could potentially be calcified chondrocytes or chondrocytes lacunae that have not yet calcified. There may be presence of Mesenchymal stem cells or vessel derived stem cells due to a blood vessel being developed near the nose cavity, which differentiate into chondrocytes
Since the adoption of the Universal Declaration of Human Rights (UDHR), the discourse of international human rights and its importance has increasingly become indoctrinated in the international community. In the context of political and economic development, there have been debates on how and which rights should be ordered and protected throughout different cultures and communities. Though there is a general acceptance of international human rights around the globe, there is an approach that divides them into civil and political rights and social and economic rights, which puts emphasis where it need not be.
"There is much pain that is quite noiseless; and that make human agonies are often a mere whisper in the of hurrying existence. There are glances of hatred that stab and raise no cry of murder; robberies that leave man of woman for ever beggared of peace and joy, yet kept secret by the sufferer-committed to no sound except that of low moans in the night, seen in no writing except that made on the face by the slow months of suppressed anguish and early morning tears. Many an inherited sorrow that has marred a life has been breathed into no human ear." George Eliot (1819-80), English novelist,editor. Felis Holt, the Radical, Introduction (1866).What is pain? In the American Heritage Dictionary, pain is referred to as "an unpleasant sensation occurring in varying degrees of severity as a consequence of injury, disease, or emotional disorder." The word is rooted in Middle English, from an Old French piene, from Latin poena, meaning "penalty or pain", and from Greek pointe, meaning "penalty." Pain is a very realistic problem that many individuals face daily.