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Before and after the discovery of penicillin essay
The advent of penicillin
Before and after the discovery of penicillin essay
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“Federal officials warned Tuesday that an especially dangerous group of superbugs has become a significant health problem in hospitals throughout the United States.” “A young girl thrust onto life support in Arizona to an uncontrollable outbreak at one of the nation’s most prestigious hospitals.” “Hospitals need to take action against the spread of a deadly, antibiotic-resistant strain of bacteria, says the Centers for Disease Control and Prevention.” You might be seeing more and more headlines about nightmare bacteria just like these. They say antibiotic resistant bacteria are rapidly becoming more prevalent and the antibiotic era is over. If this is news to you, then it also might be a surprise to know that we are heading towards a true medical …show more content…
During the pre antibiotic era in the early 1900’s the leading causes of death were tuberculosis, enteritis, and multiple strains of streptococcus, all bacterial infections. Equally terrifying was that some of these simple infections were 80% fatal if contracted. However, a breakthrough happened when Alexander fleming discovered penicillin in 1928, even though it wasn’t mass produced until 1939. Thus, the antibiotic era emerged quickly reaching its golden age (1941-1962) where they had 14 novel classes. Most were very optimistic, saying infections have basically been wiped out in America, but some people had their doubts. Flemming even predicted bacteria will develop resistance, and resistance plasmids were discovered in the 1940s but it didn’t seem to matter. After the 1960’s no new classes were being made, only little changes to the 4 remaining classes. It wasn’t until 1999 when a new class was made, so were not very fast at making antibiotics. In summary, the future for antibiotics seemed bright and limitless. However, bacterial evolutionary adaptation always seems to get the better of us in the
The Black Death (also called the "plague" or the "pestilence", the bacteria that causes it is Yersinia Pestis) was a devastating pandemic causing the death of over one-third of Europe's population in its major wave of 1348-1349. Yersinia Pestis had two major strains: the first, the Bubonic form, was carried by fleas on rodents and caused swelling of the lymph nodes, or "buboes", and lesions under the skin, with a fifty-percent mortality rate; the second, the pneumonic form, was airborne after the bacteria had mutated and caused fluids to build up in the lungs and other areas, causing suffocation and a seventy-percent mortality rate.
One measure they had was that of the “red cross”. This is where they would paint a red cross on the doors of people who were diagnosed with the plague. I think this would have worked because it would let people know who had the plague, so that they could avoid falling ill themselves.
our everyday lives bacteria is constantly surrounding us, some of the bacterium that we encounter are beneficial to us but then there are the ones that are severely detrimental to our health. The way that they effect a persons body can differ from person to person. Many of the “microscopic foes” are very resilient and have a very fast reproduction rate. Not only do they reproduce quickly they sometimes seem to outsmart our immune system and not allow our bodies to fight the infection making it almost impossible to stop them. One thing that a lot if people rely on is the assistance of prescription drugs to get them better but even the drugs are not being effective and we can’t stop the pathogens from invading our personal places such as work, home, school, or anywhere. Even though modern medicine is advancing the pathogens could still get the get the best of us. The scary thing is we never know when the next pandemic or epidemic is going to arise. All it needs is some ordinary microbe to swap genes with a deadly germ to produce a “super pathogen” and it could happen to anyone, anywhere, as it did to Jeannie Brown who is from “our neck of the woods”.
In the documentary, Hunting the Nightmare Bacteria, reporter David Hoffman investigates this new untreatable infection along two individuals and a bacterial virus within a hospital. The first individual Hoffman investigates is Addie Rerecich of Arizona, she was treated for a staph infection with antibiotics, but other complications arise. Addie had a lung transplant, she was given several different antibiotics, but her body became pan-bacteria, non-resistance to the bacteria. Addie’s life was on the edge, she had to be on life support, and finally she received new lungs. The transplant helped Addie but it would take years before could go back to normal before the infection. The second individual is David Ricci; he had his leg amputated in India after a train accident. The antibiotic treatment he received became toxic to his body increasing problems. While in India, he underwent surgery almost every day because of infections he was developing. Back in Seattle, doctors found the NDM-1 resistance gene in his body; NDM-1 gene is resistance to almost all antib...
The practice of medicine in medieval times played a very important role in society. The communities and civilizations would not have survived without the treatments that were offered. In order to have kept the population going, medicine was required. The population might have been much smaller, or even tanked without the hope of these medicines in certain cases. If the Black Death had not occurred, most of the advancements in medicine would not have taken place. While this was a devastating event in history and a misery for all of the people affected, it led the way to many new improvements in medicine. Medical recipes were developed which used the resources they had available to create relief for some of the illnesses that affected people at that time and which we still have today. The medical issues that could not be cured with the herbs and resources they had available required surgery. Compared to modern surgeries, medieval surgeries were very different. Surgery was only performed if it was the last resort and there was no other option. They had to use poisonous resources, which could be extremely dangerous. Today, we take for granted the opportunities we have with surgery, and if we need it there is sometimes no thinking twice, as in the case of someone who gets plastic surgery to change the appearance of a part of the body. Although these practices may seem like they have no affect on where we have advanced to today, they in fact do. Without the practice of medieval medical recipes and surgical practices, the medical world would not be where it is today.
The medicinal practices and problems of the Elizabethan Era were very important to the people, although they are very different from those of today. There were many different beliefs and diseases, like the Plague. Medicine was not an exact science and was related to Alchemy (Chemistry). Here, some of the many practices and beliefs of the Elizabethan Era will be discussed.
people there so that over England as a whole a fifth of the men, women
Bacterial resistance to antibiotics has presented many problems in our society, including an increased chance of fatality due to infections that could have otherwise been treated with success. Antibiotics are used to treat bacterial infections, but overexposure to these drugs give the bacteria more opportunities to mutate, forming resistant strains. Through natural selection, those few mutated bacteria are able to survive treatments of antibiotics and then pass on their genes to other bacterial cells through lateral gene transfer (Zhaxybayeva, 2011). Once resistance builds in one patient, it is possible for the strain to be transmitted to others through improper hygiene and failure to isolate patients in hospitals.
Simple infections are no longer death sentences, however, immunities to these antibiotics are appearing. The use of antibiotics save lives by crippling the ability of bacteria to damage the human body, and antibodies act as a sidekick to the immune system when fighting off life-threatening illnesses. In “The Life of a Peasant”, William Stearns Davis (1922) focuses on what life would be like for the lowest tier of people in a feudalistic state, and he concluded that often in a world without antibiotics, people lose their lives to easily preventable medical conditions, regardless of whether they are a king or a peasant. Antibiotics are used to fight infections that could otherwise prove deadly. In a time before antibiotics, life was much more difficult for all involved. Before antibiotics were used, many died of simple cuts or scratches that later got infected. If action is not taken, superbugs could grow immune to all of the antibiotics we possess. Superbugs are becoming immune to the ways we fight them, which forecasts a world without the ability to fight these superbugs. In the article “Superbugs Causing Infections at a Tertiary Care Hospital and the Return of Pre-Antibiotic Era!” Kalyan Rajkumar (2016), associate professor of microbiology at King George 's Medical University, as well as his research team, discusses the prevalence of a strain of E. coli that is mostly immune to the majority of current
Some call it “horror'; and some call it “the super germ';, but now, our always known “regular'; bacteria, those one-celled creatures once considered under control with antibiotics, have invaded our hospitals and headlines with a vengeance. The vengeance used against us is caused by an existing organism called necrotizing fasciitis, the so-called flesh-eating bacteria, caused by Group A streptococcus. What this organism does is progressively destroy the human body tissue all the way to the bone. This organism has amazingly outsmarted us of even our most potent drugs.
Medicine in the Middle Ages We are very lucky today! When we are sick, we go and see the doctor, and he or she can usually make us better with the use of medicine. It wasn‘t like this in the medieval era.
Antibiotics in general remain one of the cornerstones of modern health care, acting as something we all hope to rely on when we get sick. We could very easily name the 20th century “the age of the antibiotics,” and it would be well deserved, indeed. But time is running out. In its first global report on antimicrobial resistance, released Wednesday, the WHO says “a post-antibiotic era – in which common infections and minor injuries can kill – is a very real possibility for the 21st century.this serious threat is no longer a prediction for the future, it is happening right now in every region of the world and has the potential to affect anyone, of any age, in any country. Antibiotic resistance.is not a major threat to public health.”
Approximately one year ago in Kentucky, a man went to sleep thinking he might have caught a flu. The next day, he is rushed to the local hospital while coughing up chunks of lung tissue; within a few hours he experiences organ failure and lips into a coma. Over the next two days, two other patients come in with the same symptoms and die almost immediately. This epidemic that swept over this small area in Kentucky was an ultra resistant strain of staph infection known as MRSA, or methicillin-resistant Staphylococcus aureus (Eisler, 2013). MRSA and other species of resistant bacteria have arisen from the global overuse of antibiotics. Over the years, resistant strains of bacteria have become more and more difficult to fend of using common antibiotic treatments. If something is not done to stop antibiotic resistance, completely resistant strains of bacteria, which we will be unable to kill through use of antibiotics.
Healthcare-associated infections (HAIs) have been a persistent problem in the United States for decades. Yang et al. (2013) stated that “Nosocomial infections or healthcare-associated infections are defined as a localized or systemic condition resulting from an adverse reaction to the presence of an infectious agent or its toxin. There must be no evidence that the infection was present or incubating at the time of admission to the acute care setting” Also if infections occur within 48 hours of being discharged from the hospital or a healthcare setting, then it is considered as a healthcare-associated infection (Daud-Gallotti et al., 2012). Healthcare-associated infections can be easily prevented, however they are held accountable for hundreds of thousands of deaths for the past few decades. They have been known to increase rates of drawn-out hospital stays, cost, morbidity, mortality, and readmission to the hospital (Montoya & Mody, 2011). When antibiotic-resistant organisms (AROs) are involved with these types of infections, the rates are expanded even further and usually cause many more fatalities (Srigley, Lightfoot, Fernie, Gardam & Muller, 2013).
...gests that the world is on the brink of a post-antibiotic era as the numbers of resistant bacteria (superbugs) proliferate, and there is an increase in the number of people dying from previously treatable infections. Todar, (n.d) states, “Society could be faced with previously treatable diseases that have become again untreatable, as in the days before antibiotics were developed.”