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Essay of DNA discovery
Discovery of dna essay
Discovery of dna essay
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Discoveries in DNA, cell biology, evolution, and biotechnology have been among the major achievements in biology over the past 200 years with accelerated discoveries and insight’s over the last 50 years. Consider the progress we have made in these areas of human knowledge. Present at least three of the discoveries you find to be the most important and describe their significance to society, heath, and the culture of modern life.
DNA (deoxyribonucleic acid) is a self-replicating molecule or material present in nearly all living organisms as the main constituent in chromosomes. It encodes the genetic instructions used in the development and functioning of all known living organisms and many viruses. Simply put, DNA contains the instructions needed for an organism to develop, survive and reproduce. The discovery and use of DNA has seen many changes and made great progress over many years. James Watson was a pioneer molecular biologist who is credited, along with Francis Crick and Maurice Wilkins, with discovering the double helix structure of the DNA molecule. The three won the Nobel Prize in Medicine in 1962 for their work (Bagley, 2013). Scientist use the term “double helix” to describe DNA’s winding, two-stranded chemical structure. This shape looks much like a twisted ladder and gives the DNA the power to pass along biological instructions with great precision.
The scientific and medical progress of DNA as been emense, from involving the identification of our genes that trigger major diseases or the creation and manufacture of drugs to treat these diseases. DNA has many significant uses to society, health and culture of today. One important area of DNA research is that used for genetic and medical research. Our abi...
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...rom http://www.dnaforensic.org/index.html.
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ALCOR. (2013). Cryonics. In Alcor Life Extension Foundation. Retrieved December 30, 2013, from http://www.alcor.org/.
Wolf, A. (2011). What is cryonics?. In Institute for Evidence-Based Cryonics. Retrieved December 30, 2013, from http://www.evidencebasedcryonics.org/what-is-cryonics/.
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It helps medics to find a direct genetic cause of the patient’s condition and target it with pharmaceutical or other therapies. The technology is used for the identification of DNA sequences that increase risks of current diseases and disorders; with this information carriers can start to make efforts to prevent them before the development of the problem. The video mentioned 200 actionable genes, structures that have direct links with a specific condition. Knowing about their presence, people have a chance to bring in preventive measures like taking anticoagulants in the case of identification of a thrombogenic gene. The technology led to the significant improvement of diagnostics and personalized treatments. It helped to find a rare, life-threatening mutation in case of Beery twins and assign a drug to a girl (Alexis) that returned her to a normal life. In the case of cancer genome sequencing led to the development of genetic drags, which target essential tumor genes and make malign structures to shrink. The video mentioned a product that works with the BRАF protein that induces cells to uncontrolled division; the drug led to the remission in the patient with metastasizing melanoma. Such treatment was effective in the case of cystic fibrosis. In the case of the breast cancer the technology helps to evaluate the aggressiveness of the condition and make a personalized decision about chemotherapy. The video also mentioned the pre-implantation genetic diagnosis – an early-staged technology that prevents the development of inherited disorders in
The following is a review of the book, The Double Helix, by James D. Watson that was published in 1968. Here the Norton Critical Edition will be used for page numbering and insights for this review, which was edited by Gunter S. Stent and published in 1980. The Double Helix is a personal recollection of the period of time when the structure of DNA was discovered. James D. Watson (Watson) along with Francis Crick (Crick) were the two scientists who published a paper in 1953 which purposed a structure for DNA. For the most part their structure has stood the test of time, and since that time period many people have wanted to know details of how they discovered DNA’s structure (pp. 3). Therefore Watson’s purpose in writing the book was to describe his personal view of the events that lead to discovery of DNA’s three-dimensional structure, when they happened in 1952-53. He is well qualified to give an account of these things, for he was there in the middle of everything; he was one of the main players. In order to describe the events, apart from his sharp memory, Watson used letters he wrote to his family to help him remember dates and details, as well as suggestions from his associates who reviewed his manuscript. In the following paragraphs I will summarize the text, and follow that with my own review of
In April of 1953, James Watson and Francis Crick published a game changing paper. It would blow the mind of the scientific community and reshape the entire landscape of science. DNA, fully knows as Deoxyribonucleic Acid is the molecule that all genes are made of. Though it is a relatively new term with regard to the age of science, the story of DNA and the path to its discovery covers a much broader timeframe and had many more contributors than James Watson and Francis Crick. After reading the paper the audience should have a better understanding of what DNA is, the most important experiments that contributed to its ultimate discovery and the names and contributions of the lesser-known scientists that helped Watson and Crick turn their idea
PubMed Health (n.d.). How does the immune system work? Retrieved April 8, 2014, from http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0010386/
"The discovery of the structure by Crick and Watson, with all its biological implications, has been one of the major scientific events of this century." (Bragg, The Double Helix, p1) In the story of The Double Helix, James Watson tells of the road that led to the discovery of life's basic building block-DNA. This autobiography gives insight into science and the workings within a professional research laboratory that few members of society will ever be able to experience. It also gives the reader an idea of the reality of life for one scientist and how he struggled with the problem of DNA. However, the author's style is marked by his lack of objectivity and inclusion of many biased opinions and personal prejudices.
DNA underlies almost every aspect of human health, both in function and dysfunction. Obtaining a detailed picture of how genes and other DNA sequences function together and interact with environmental factors ultimately will... ... middle of paper ... ... rgy-related agents, especially in terms of cancer risk. Although there could be great benefits in human health and disease, some people are not happy with the work being done on the Human Genome Project and say its unethical and that the money could be better spent on other things like improving the health of very poor people that probably won’t benefit from the project and who will continue to be vulnerable to infectious diseases.
Palermo, E. (2013, August 28). How Does Newton's Cradle Work? Retrieved May 17, 2014, from www.livescience.com: m.livescience.com/39271-how-does-newtons-cradle-work.html
Although humans have altered the genomes of species for thousands of years through artificial selection and other non-scientific means, the field of genetic engineering as we now know it did not begin until 1944 when DNA was first identified as the carrier of genetic information by Oswald Avery Colin McLeod and Maclyn McCarty (Stem Cell Research). In the following decades two more important discoveries occurred, first the 1953 discovery of the structure of DNA, by Watson and Crick, and next the 1973 discovery by Cohen and Boyer of a recombinant DNA technique which allowed the successful transfer of DNA into another organism. A year later Rudolf Jaenisch created the world’s first transgenic animal by introducing foreign DNA into a mouse embryo, an experiment that would set the stage for modern genetic engineering (Stem Cell Research). The commercialization of genetic engineering began largely in 1976 wh...
Nordqvist, Christian. “What is serotonin? What does serotonin do?”. Medical News Today. Medicalnewstoday.com, 3 Nov 2013. Web. 18 Apr. 2014.
If you’ve ever seen the Austin Powers movie I’m sure you remember the part where they cryogenically freeze Austin and then thirty years later thaw him out to save the world. While we all know Austin Powers isn’t real, I’m sure you wondered if this freezing could be done in real life. Today we will look at what exactly cryonics is, what businesses claim to provide it, the procedure and its risks.
Harris, T. (n.d.). how body armor works. Retrieved March 3, 2014, from How stuff works: http://schienc.howstuffworks.com/body-armor.htm
The Double Helix tells a tale of fierce competition, perseverance, and scientific innovation as we follow James Watson and his cohort Francis Crick on their quest to discover the secret to life, the structure of deoxyribonucleic acid. Although already fascinated with DNA, Watson struggled with finding chemistry exciting enough to learn it in depth. He had studied birds in college and thereby managed to avoid any formal chemistry or physics courses. As he later pursued a PhD in biochemistry, he realized he could put it off no longer and attempted to learn organic chemistry at Indiana University. However, after a mishap in the lab, he was encouraged instead to study nucleic acid chemistry with Herman Kalckar in Copenhagen. There, his mind strayed from his work and he began doing unauthorized research in the lab of Ole Maaløe, studying phages. Herman stopped teaching Watson after going through a divorce with his wife, and sent Watson off to a scientific conference in Naples. Although he was bored by many of the lectures, Maurice Wilkins’s talk about X-ray diffraction fascinated Watson. He was struck by an X-ray diffraction picture of DNA that Maurice presented and was determined to study the acid. He later got to know more about Maurice’s colleague, Rosalind Franklin, who was proud, stubborn, and very difficult to work with. Watson greatly admired the lecture given by the renowned Linus Pauling, who had discovered the structure of the alpha-helix and was thought of as the leader in DNA research in the scientific world.
the feats that people have achieved with the use of DNA. The discovery of the
The study of replication, transcription and translation of genetic material is known as molecular biology. Molecular biology is a bottom-up approach to understanding human life. Though the exploration of molecular biology began in the 1930s, it really took off in the 1960s after the uncovering of the structure of DNA. (Coriell Institute for Medical Research, n.d.) Today, molecular biology is shaping our understanding of diseases. Through this reflection journal, I seek to explore preventative and curative phenomena in medical biotechnology, and determine their impact on the political, social and economic spheres.
...f the structure of DNA by James Watson and Francis Crick in 1953 that was extremely influential for future researchers. They determined that DNA was a double helix structure composed of base pairings, with a sugar phosphate backbone. This model explained how “genes can duplicate themselves [and] would eventually lead to our current understanding of many things, from genetic disease to genetic engineering” (Salem).