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Quizlet for renal system
Usmle renal physiology
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Explain the blood supply for the kidney 12
A system of blood vessels allows the exchange of materials that occurs in the kidneys. A renal artery branches off the abdominal aorta and enters the renal sinus of each kidney. Segmental arteries diverge from the renal artery to form interlobar arteries, which ascend within the renal columns toward the renal cortex. Branches from the interlobar arteries diverge near the base of each pyramid and arch over the bases of the pyramids to form the arcuate arteries. Interlobular arteries project from the arcuate arteries into the cortex, and afferent arterioles are derived from the interlobular arteries or their branches. The afferent arterioles supply blood to the glomerular capillaries of the renal corpuscles.
Efferent arterioles arise from the glomerular capillaries and carry blood away from the glomeruli. After each efferent arteriole exits the glomerulus, it gives rise to a plexus of capillaries, called the peritubular capillaries, around the proximal and distal convoluted tubules. Associated with the juxtamedullary nephrons are specialized sets of peritubular capillaries called the vasa recta. The peritubular capillaries drain into interlobular veins, which in turn drain into the arcuate veins. The arcuate veins empty into the interlobar veins, which drain into the renal vein. The renal vein exits the kidney and connects to the inferior vena cava. Seeley, R., VanPutte, C., Regan, J., & Russo, A. (2011). Seeley's Anatomy and Physiology (9th ed.). New York, New York: McGraw-Hill
As for the kidney’s, they consist of a renal cortex with arcuate vessels surrounds the renal medulla of the kidney. The renal papilla at the end of the renal medulla connects to the renal pelvis. Finally, a ureter descends form the kidney to the urinary bladder in both the mink and human.
The kidneys are located in the posterior section of the retroperitoneal cavity and are small, dark red kidney-bean shaped organs in the lower part of the rib cage (Marieb, The Urinary System, 2015). They are undervalued organs considering how essential they are for the body’s ability to maintain homeostasis. The kidneys filter about 120-150 quarts of blood to produce about 1-2 quarts of urine each day (NIH, 2014). Blood initially enters the kidneys through the renal artery. It then flows into the segmental artery before moving into the interlobar artery. From the interlobar artery the filtrate enters the arcuate artery before branching into the cortical radiate artery, which feeds into the afferent arteriole, before passing into the glomerulus where it begins to filter out waste. The filtered waste is then collected by renal tubule. The tubules drain to collecting ducts and all of these components together makes up a small unit called a nephron. Each kidney has over a million nephrons (Marieb, Blood Supply/ Nephrons, 2015). They filter out wastes that run through different body systems via blood; the majority of that waste is nitrogenous wastes, toxins, excess fluids, electrolytes, and drugs. These waste products are eliminated as urine. While waste are removed vital enzymes, hormones, and water are returned
Anomalous systemic arterial supply to the lungs has been extensively described in association with other congenital abnormalities such as bronchopulmonary sequestration and hypogenetic lung syndrome (scimitar syndrome). In 1946, Pryce introduced the term ‘sequestration’ to describe congenital abnormalities characterised by an anomalous systemic arterial supply to the lung and atresia or hypoplasia of the pulmonary artery. Sequestration was defined by Pryce as a “disconnected (dislocated, ectopic) bronchopulmonary mass or cyst with an anomalous systemic blood supply”.
The smallest arteries are called arterioles and they play a vital role in microcirculation. Microcirculation deals with the circulation of blood from arterioles to capillaries to venules the smallest veins. The liver, spleen and bone marrow contain vessel structures called sinusoids instead of capillaries. In these structures blood flows from arterioles to sinusoids to venules.
The cardiovascular system - The cardiovascular system is responsible for transporting nutrients and removing gaseous waste from the body. It consists of the heart, which powers the whole process, the veins, arteries, and capillaries, which deliver oxygen to tissue at the cellular level. The cardiovascular system carries blood that is low in oxygen away from the heart to the lungs via arteries, where oxygen levels are restored through the air once oxygenated, this blood is then carried throughout the body via arteries, keeping our organs and tissue alive. The cardiovascular system is the workhorse of the body, continuously moving to push blood to the cells. If this important system ceases its work, the body dies.
According to Batshaw, Roizen, and Lotrecchiano (2013), patent ductus arteriosus (PDA) is “the persistence of a fetal passage permitting blood to bypass the lungs” (p. 745). This is an inherited heart condition in which the ductus, a small pathway between the pulmonary and the aortic, valves remain open. This cardiovascular problem usually occurs in low birth weight infants. The blood vessels usually naturally closes after birth (Batshaw et al., 2013, p. 96). It becomes atypical if it remains open after the neonatal period. The structure usually closes in typical developing newborns around the initial 24 hours, and anatomical closure is supposed to follow several weeks later (Stanford Children’s Health, 2015). At the point when the ductus arteriosus stays open, the blood from the oxygen-rich aorta blends with the oxygen-poor pulmonary artery causing the higher chance of blood pressure in the lung pathways (U. S. Department of Health and Human Services, 2011). Certain children who have patent ductus arteriosus may be given medication, relying upon the circumstance to standardize the blood and oxygen levels until surgery is performed. Doctor can treat this condition by providing pharmaceutical medicine, catheter-based procedures, and surgery (U. S. Department of Health and Human Services, 2011).
The Structure and Functions of the Arteries Arteries are blood vessels that convey blood from the heart to the tissues of the body. The arteries expand and then constrict with each beat of the heart, a rhythmic movement that may be felt as the pulse. Arteries are usually named from the part of the body that they are found, for example; brachial artery found in the arms, metacarpal artery found in the wrist; or from the organ which they supply as the hepatic artery supplies the liver, pulmonary artery brings deoxygenated blood the lungs. The facial artery is the branch of the external carotid artery that passes up over the lower jaw and supplies the superficial portion of the face; the haemorrhoidal arteries are three vessels that supply the lower end of the rectum; the intercostal arteries are the arteries that supply the space between the ribs; the lingual artery is the branch of the external carotid artery that supplies the tongue. The structure of the artery enables it to perform its function more efficiently.
Heart Disease. Those two words often conjure images of an elderly man clutching his chest in a fit of pain and subsequently succumbing to a heart attack. Those two words describe the leading cause of death in Americans--nearly 25%1. Unfortunately, many specific heart problems fade away and fall under the umbrella of only two words. This research paper will discuss one of those heart problems, aortic dissection, in much more detail, than just two little words.
(5) NIH Publication No. 03–4241. Your Kidneys and How They Work. National Kidney and Urologic Diseases Information Clearinghouse, 2003. http://kidney.niddk.nih.gov/kudiseases/pubs/yourkidneys/
The urinary tract consists of two kidneys, to ureters, urethra, and the urinary bladder. The urinary system works to remove waste from the body, maintain homeostasis of water, blood pressure, and regulate the body’s pH levels. The kidneys regulate several important internal conditions by excreting substances out into the body. After urine has been produced in the kidneys it is then transported to the urinary bladder via the ureters. The urinary bladder then holds the urine until the body is ready for excretion through the urethra.
The term, ischemia, denotes inadequate blood supply to tissues due to blockage of the arterial inflow, while, reperfusion injury is defined as the injury caused by the restitution of blood flow after an ischemic peroid, leading to death of cells that were only reversibly injured at the time of blood flow restitution. [63]. The final infarct size after an MI event is therefore the result of the ischemic and reperfusion damage. For this reason, the term that best describes this process of myocyte death in reperfused MI is myocardial ischemia/reperfusion (I/R) injury [64]. In the early hours post myocardial ischemia, injured cardiac cells can release several molecules, including adenosine, opioids, and bradykinin, which activate the G protein signaling pathways therefore promoting myocardial survival. While in the late phase, myocardial ischemia induces upregulation of growth factors and cytokines, including VEGF, ILGF and SDF-1, in the injured myocardium, hence promoting a cardio-protective state. The liver also participates in cardioprotection through the up regulation and release of secretory proteins, including FGF21 and TFF3, which also promote cardiomyocyte survival. [65]. Foundational studies performed about three decades ago with animal models demonstrated that an early reperfusion was able to limit infarct size [66]. Then fibrinolysis was indisputably associated with a decrease in mortality in patients with STEMI [67].A decade later; primary angioplasty was shown to be more superior than fibrinolysis [68]. Currently primary coronary angioplasty (PCI) has been established as the backbone treatment for STEMI patients. The period from the onset of symptoms of MI (representative of the time of coronary occlusion) and reperfusio...
Peripheral artery disease is usually caused by atherosclerosis, which is when fatty deposits accumulate in the arteries of, most likely, limbs. This does affect all arteries throughout the body, then in turn, slowing the blood flow. PAD may also be due to inflammation of the blood vessels, injury to the extremities, or even exposure to radiation. “Peripheral arterial disease (PAD) affects approximately 10% of the American population” (Gurbir Dhaliwal; Peripheral arterial disease: Epidemiology, natural history, diagnosis and treatment; 2007). If not taken care of, PAD may lead to critical limb ischemia, open sores on the feet or legs that become infected by gangrene. The gangrene is then removed surgically, but doctors might have to amputate the extremity all together. Another issue that arises with PAD if it is not under control is the risk of stroke or heart attack. These can cause death to part of the heart or brain, or even death itself. The population more at risk would be smokers, diabetics, people who are obese, those with hypertension or hyperlipidemia, over the age of 50, have a family history of PAD, or those with a high level of homocysteine. If someone does fall into a few of these categories a physician can do a few tests to check for PAD. The doctor will more than likely start off with a physical exam, blood test, and possibly an ultrasound. From there the physician may try an ankle-brachial index, or ABI, which compares the blood pressure of the feet to the blood pressure of the arm. “An American survey of 2174 patients older than 40 years of age used the ankle-brachial index (ABI) as a screening tool, and showed a PAD prevalence of 0.9% between the ages of 40 and 49 years, 2.5% between the ages of 50 and 59 years, ...
The cardiovascular system is the most important system in our body. This system is what keeps us alive. Beating on average 30 billion times a year, our heart is never able to stop and take a break. With every beat of our heart, the cardiovascular system moves blood, gases, nutrients, and hormones throughout the intricate vasculature of our bodies. An adult body contains over 60,000 miles of vessels, which can wrap around the world two and a half times. The vessel branching off of the heart is largest artery in our body and is known as the aorta. The aorta supplies oxygenated blood to our body. The aorta runs along the midline of our body and has many other vessels that stem from it to deliver the blood to a specific location. The aorta has several different names, depending on the location in the body. As it comes off of the heart at the left ventricle it is called the ascending aorta. It is located in the anterior mediastinum and is approximately three to five centimeters wide. In the superior mediastinum, at the peak of the aorta, it turns to resemble and upside down U and become the aortic arch. As it pass behind the heart and starts to go down into the thoracic cavity it becomes the descending aorta, more specifically, the thoracic aorta. The diameter of the thoracic aorta is about two and a half centimeters wide. Once the aorta reaches the diaphragm and passes into the abdomen it converts the abdominal aorta. The abdominal aorta is about two centimeters wide. The thoracic aorta runs for about twenty centimeter and the abdominal aorta extends for about fifteen centimeters long.
All play a role in removing waste from your body. Your kidneys filter waste from your blood and regulate the concentrations of many substances. Tubes called ureters carry urine from your kidneys to the bladder, where it’s store until it exits your body through the urethra.
It is the main nitrogenous excretory product of humans. Each kidney receives its blood supply from the renal artery. The kidney consists of millions of filtering units called nephrons. Blood comes to the kidney under high pressure to make filtration efficient.