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Essay about Rosalind Franklin
James Watson and his contribution to DNA
James Watson and his contribution to DNA
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Recommended: Essay about Rosalind Franklin
Franklin, Rosalind (1920 - 1958)
Franklin was a Londoner by birth. After graduating from Cambridge
University, she joined the staff of the British Coal Utilisation
Research Association in 1942, moving in 1947 to the Laboratoire
Centrale des Services Chimique de L'Etat in Paris. She returned to
England in 1950 and held research appointments at London University,
initially at King's College from 1951 to 1953 and thereafter at
Birkbeck College until her untimely death from cancer at the age of
37.
Franklin played a major part in the discovery of the structure of DNA
by James Watson and Francis Crick. With the unflattering and distorted
picture presented by Watson in his The Double Helix (1968) her role in
this has become somewhat controversial. At King's, she had been
recruited to work on biological molecules and her director, John
Randall, had specifically instructed her to work on the structure of
DNA. When she later learned that Maurice Wilkins, a colleague at
King's, also intended to work on DNA, she felt unable to cooperate
with him. Nor did she feel much respect for the early attempts of
Watson and Crick in Cambridge to establish the structure.
The causes of friction were various ranging from simple personality
clashes to, it has been said, male hostility to the invasion of their
private club by a woman. Despite this unsatisfactory background
Franklin did obtain results without which the structure established by
Watson and Crick would have been at the least delayed. The most
important of these was her x-ray photograph of hydrated DNA, the
so-called B form, the most revealing such photograph then available.
Watson fir...
... middle of paper ...
...anklin's showing an image of the now famous Photo 51.
Franklin, went on to study the tobacco mosaic virus, and continued her
work in absolute dedication, despite having been diagnosed with cancer
in 1956 (probably due to the chemicals she was using). She died two
years later, 37 years old, never knowing how much her work had played
a role in Watson and Crick's discovery. In 1963 they received the
Nobel prize for their discovery, along with Wilkins, Franklin's
collaborator. In 1968 Watson's popular book, The Double Helix,
recounted the events leading to their ultimate discovery, making clear
for the first time how critical Franklin's experimental work had been.
Franklin's social isolation prompted by the contempt male scientists
showed toward her as a woman-scientist, is one of the tragedies in the
history of science.
Francis Crick: He does the same research with Watson and they are both teammates. He is also eager to know what is in DNA and the relationship of it with the double-helix, but at the same time is disorganised, and expected Watson to do a majority of work.
...ed some credit. People see the novel as a poor presentation of who she was and how important her ideas really were. However, I see that both are to blame. Franklin could have worked closer with Watson instead of withholding her results; Watson could have mentioned her in his work earlier on. I believe that this competitiveness between scientists was beneficial overall. This rivalry provided motivation and even though defeat seemed so near at times, they were able to persevere. There are several ways that Watson and Crick could have found the answer but I believe it is for the best that these events occurred the way they did because the ending result justifies all previous actions. The rivalry that sparked between these scientists yielded some negative results but it led to something even greater: the secret of life.
Benjamin Franklin has been without a doubt one of the most relevant individuals in US history. His autobiography gives us a brief but detailed summary of what his life was like and how society worked in the eighteen century. This autobiography gives us many details of how the colonies where and offers and an overall image of the development of British North America which later turned into the United States. Due to the fact that this book was originally written for Franklin's son, the book concentrates in personal information and has very little information about other topics. However, there are some topics that can be extracted from his writings; one of them is gender. Even though, Franklin never talks openly about gender, we can observe how in his writing these roles are clearly assigned. In this paper, we will analyze how Benjamin's Franklin autobiography showcases the importance of gender in the early eighteenth century. Gender can be analyzed in Franklins book by looking at different topics. This given to men and women by society can be seen in the workspace, in the education of each individual, and in the family and family structure.
John Hope Franklin’s childhood had a huge impact on his life and scholarship. His parents were a primary influence in his education and much of the subjects he was passi...
Benjamin Franklin was a remarkably talented man. He started his life as a printers apprentice, but went much farther then there. He developed things that were far more advanced than the time. Benjamin Franklin's stove for example, for cold winter nights, and bifocal lenses for reading. Franklin tracked storms to help understand the horrible weather endured by the colonies. But gis study of electricity made him mist famous and he was known world wide as the founder of the lightning rod. Not only was Benjamin Franklin helpful in developing ideas for better living, he was also a strong force in developing the new nation of America. Benjamin Franklins political views showed him to be a man who loved freedom and independence. His views towards England gradually changed from like to dislike until he finally
...or instance, hepatitis C virus), biological molecules (such as cyclic adenosine monophosphate), and Human Immunodeficiency (HIV) virus (Bauman et. al. 2011). Rosalyn had went farther in the world of science than anyone including her self thought was possible (Bauman et. al. 2011). Rosayln and Berson changed history, altered the way science was perceived and their time, and how today we see and research science.
The following is a review of the book, The Double Helix, by James D. Watson that was published in 1968. Here the Norton Critical Edition will be used for page numbering and insights for this review, which was edited by Gunter S. Stent and published in 1980. The Double Helix is a personal recollection of the period of time when the structure of DNA was discovered. James D. Watson (Watson) along with Francis Crick (Crick) were the two scientists who published a paper in 1953 which purposed a structure for DNA. For the most part their structure has stood the test of time, and since that time period many people have wanted to know details of how they discovered DNA’s structure (pp. 3). Therefore Watson’s purpose in writing the book was to describe his personal view of the events that lead to discovery of DNA’s three-dimensional structure, when they happened in 1952-53. He is well qualified to give an account of these things, for he was there in the middle of everything; he was one of the main players. In order to describe the events, apart from his sharp memory, Watson used letters he wrote to his family to help him remember dates and details, as well as suggestions from his associates who reviewed his manuscript. In the following paragraphs I will summarize the text, and follow that with my own review of
The Autobiography of Benjamin Franklin is a representation of the new prospect of upward mobility in colonial America during the 18th century and the development of the Age of Reason, which assisted in the conception of the idea of the “American Dream”; a dream that includes fundamentally social ideals such as democracy, equality, and material prosperity. Furthermore, Franklin’s autobiography exemplifies a significant shift in focus from religion to enlightenment and reason. Additionally, there were forces specific to Benjamin Franklin's Philadelphia, that played an important role in his perspectives and the changes that occurred within colonial America during the 18th century.
In The Autobiography, Benjamin Franklin recounts the many paramount experiences throughout his life that shaped him into great American figure he was known to be. On the opening page, Franklin reveals the book’s epistolary format by writing, “Dear Son,” going on to admit that he’s made some mistakes in the past and to recollect that past is a way to relive it. By divulging his desire to “change some sinister Accidents & Events” (Franklin 3) the author indicates how important it is for his son to observe as he amends his mistakes. Pride, virtue and vanity play a pivotal role in Benjamin Franklin’s life and the way he portrays himself to others. Instances occur where the author is shown gloating about his great accomplishments and he puts emphasis on his need to live a virtuous and morally perfect life. Throughout his story, Benjamin Franklin tells his son of his many virtuous acts and momentous achievements, motivating the question as to whether he seeks his own approval more so than the approval of his peers.
	X-ray crystallography helped determined the three dimensional structure of DNA when Franklin returned to England. She became the first person to find the molecule¡¯s sugar-phosphate backbone while working with a team of scientists at King¡¯s College in London. Unfortunately, leadership misunderstandings and personality conflicts depreciated Franklin¡¯s effectivness in the laboratory. Maurice Wilkins, the laboratory¡¯s second in command, returned from a vacation expecting Franklin to work under him. Franklin came to the laboratory with the understanding that she would be researching alone. While Franklin was direct and decisive, Wilkins tended to be alluding and passive-aggressive. As Franklin made further advances in DNA research, Wilkins secretly shared her findings with the famous duo of Watson and Crick, who were then working at Cambridge. Franklin¡¯s discoveries fueled their research machine, allowing them to advance beyond others in the field. They would eventually publish on DNA structure in 1953. Due to discriminatory procedures at King¡¯s College, Franklin eventually left to become the lead researcher at London¡¯s Birbeck College--upon agreeing not to work on DNA. She furthered her studies in coal and made significant advances in virology. Franklin died in 1958 of ovarian cancer. She lived 37 monumentally significant years.
In the first several chapters of The Double Helix, James Watson gives detailed descriptions of the places and people who were of some importance in this charade of science. Watson wrote of his personal history and of how he arrived at the Cavendish Laboratory in Cambridge. In this laboratory was a yet-unknown thirty-five year old man named Frances Crick . When Watson joined the team at Cavendish it was to help continue studies on the structure of proteins. Some of the people in the lab that Watson mentioned were Sir Lawr...
She began her studies at St. Paul’s Girls’ School with her family discouraging her from aiming to get into the scientific field, mainly because it was difficult for a woman of that time. She gained a degree in physics with a specialty in chemistry from Newnham College before receiving admission to Cambridge University. Unfortunately, her father was opposed to the education of women and refused to pay for Rosalind’s tuition. Luckily, an aunt stepped up and offered to pay for her education, feeling that Rosalind should attend school. Her own mother was also in favor of Rosalind receiving an education and soon her father gave in.
So, while this woman has never been in the limelight, she pioneered molecular genetics as it is today. Without her stubborn need for the facts, the human genome would still be an enigma to us today. She is truly a role model for all women today.
In whatever Franklin did, she wholeheartedly pursued it with her heart and gave her full potential. Despite her thorough and diligent ways of conducting her work and research, it did not mean she was respected by everyone. In fact, during her time at King’s College London, Franklin did not get along with her colleague, Maurice Wilkins. Without Franklin’s permission or knowledge, Wilkins disclosed Franklin's photograph 51 to competing scientist James Watson, who was also working on DNA. Eventually, James Watson and his partner Francis Crick used Franklin’s photograph 51 to back up their theory of the DNA model structure. It was due to the conflict between Franklin and Wilkins that played a key factor in Franklin leaving King’s College and relocating to Birkbeck College. Franklin’s life and career was cut short when Franklin discovered she had ovarian cancer and passed away on April 16, 1958, at the age of only 37. Nevertheless, Franklin still managed to contribute immensely to physics and the world in many
Though there were other women in the science world at the time, as stated before, it was mainly male-dominated. Though she got along well with her male counterparts in the Laboratoire Central des Services Chimiques de l'Etat in Paris, she sometimes felt that there was still an “elite boy’s club” culture established by the lack of female scientists. This feeling only got worse when, after being over-exposed to x-rays, she decided to move back to England to continue her work in crystallography. She was offered a position at the King’s College, where she was put down and subordinated by the men in the laboratory, especially Maurice Wilkins, who was in conflict with her over who was in charge. This was due to miscommunication and most likely of the fault of the J.T Randall, the director of the biophysics