Dilated Cardiomyopathy
(Slide 2) What is Cardiomyopathy? If we break down the word we can see “Cardio” which means of the heart, “myo” which means muscle, and “pathy” which means disease, therefore cardiomyopathies are diseases of the heart muscle. (Slide 3) There are 3 main types of cardiomyopathies; hypertrophic, dilated, and restrictive. I will only be discussing dilated cardiomyopathy, which is characterized by the enlargement of the hearts chambers with impaired systolic function. It is estimated that as many as 1 of 500 adults may have this condition. Dilated cardiomyopathy is more common in blacks than in whites and in males than in females. It is the most common form of cardiomyopathy in children and it can occur at any age (CDC).
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Most often the disease starts in the left ventricle, and then often spreads to both the atrium and right ventricle as well. Usually there will also be mitral and tricuspid regurgitation, due to the dilation of the annuli. This regurgitation will continue to make problems worse by adding excessive volume and pressure to the atria, which is what then causes them to dilate. Once the atria become dilated it often leads to atrial fibrillation. As the volume load increases the ventricles become more dilated and over time the myocytes become weakened and cannot contract as they should. As you might have guessed with the progressive myocyte degeneration, there is a reduction in cardiac output which then may present as signs of heart failure (Lily).
(Slide 5) Dilated cardiomyopathies results from a wide spectrum of genetic, inflammatory, toxic, and metabolic causes. However, at least 750,000 of the over 300 million U.S. population are likely to have idiopathic (ie: the cause is unknown) dilated cardiomyopathy (Hershberger). (Slide 6) Although many cases are currently classified as idiopathic, some examples of known causes include specific gene mutations, chronic excessive alcohol ingestion and other recreational drug use, chemotherapy, pregnancy, and viral myocarditis
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Alcohol consumption will need to be discontinued, especially if this is a cause. Moderate exercise should be encouraged within the limitations of the patient (Bennett). Medical treatment is generally aimed at relieving symptoms of heart failure and improving cardiac output. Patients are often given medications such as ACE inhibitors and Beta-blockers. Antiarrhythmic drugs, implantable defibrillators, and pacemakers are other treatments used for dilated cardiomyopathy patients. Anticoagulants are also an important treatment for dilated cardiomyopathy patients due to the increased risk of developing thrombus from poor systolic function, atrial fibrillation, and poor circulatory flow. Cardiac transplantation is another treatment option but heart donors are very limited (Lily).
Dilated cardiomyopathy accounts for approximately 15% of heart failure cases in the under 75s (“Chronic Heart Failure”). Patients with Dilated cardiomyopathy are usually unaware of the disease until they experience the signs and symptoms of heart failure or they develop an arrhythmia.
In conclusion it is important to remember that dilated cardiomyopathy is the most common form of cardiomyopathy. There are a variety of acknowledged triggers but often the cause of the dilated cardiomyopathy is unknown. Early identification of the disease aids in proper medical care and may
Hypertrophic Cardiomyopathy, also known as HCM, is a type of heart disease that affects the Cardiac Muscles and Cardiac Muscle cells. This disease occurs if the Cardiac Muscle cells enlarge, which causes the wall of the heart’s ventricles (most often the left ventricle) to thicken. It can also cause stiffness in the ventricles, as well as mitral valve and cellular changes.
Cardiomyopathy, by definition, means the weakening of the heart muscle. The heart is operated by a striated muscle that relies on the autonomic nervous system to function. Cardiomyopathy is diagnosed in four different ways based on what caused the illness and exactly what part of the heart is weakened. The four main types of cardiomyopathy are dilated cardiomyopathy, hypertrophic cardiomyopathy, restrictive cardiomyopathy, and arrhythmogenic right ventricular dysplasia. One other category of cardiomyopathy that is diagnosed is “unclassified cardiomyopathy.” Unclassified cardiomyopathy is the weakening of the heart that does not fit into the main four categories.
In case of chronic stage, treatment of cardiomyopathy is mainly symptomatic and similar to the treatment of the other causes of heart disease. There may be a need for a pacemaker and a heart transplant can be considered.
Hypertrophic cardiomyopathy is a genetic disease of the heart, making the cardiac muscle is thick and strong. The thick muscle causes a decrease in cavity size, forcing the heart to pump less blood. Hypertrophic cardiomyopathy is one of the primary causes of sudden death as the prevention of blood flow causes cardiac arrest. More successful research is being conducted on HCM, including research on the genetics associated and the heredity of the genes. Unfortunately this disorder effects many young athletes due to their increased stresses of training on their heart. However, despite the use of new technology such as the electrocardiogram and transthoracic echocardiogram, the strategies are limited, restricting new answers.
Capture Myopathy? Not very often a diagnosis is termed liked this, especially in the field of human medicine, especially n the field of cardiology the where the term myopathy is revered as Cardiomyopathy. Myopathy is a disease that affects the muscles and causes weakness due to dysfunction of muscle fibers (1); Cardiomyopathy is of the same circumstance but deals primarily with the heart. Capture Myopathy is relative to many animals, especially mammals and provides a definitive correlation to humans and their potential medical prognosis of Cardiomyopathy. Capture Myopathy is a syndrome that that occurs within captive animals and causes rapid death through excessive adrenaline within the bloodstreams. (3) Capture Myopathy is quite often referred to as white muscle disease, the muscle when used causes a change of metabolism from using oxygen to using the stored energy within the muscle. The change up allows for lactic acid to build up and make its way into the bloodstream where it changes the homeostasis of the body: the body pH and the heart output. In essence, if the heart is inefficiently pumping the correct oxygen to the muscle, the muscle will begin to deteriorate and ultimately lead to damages to the kidney and the effector organs. (2) Animal Capture Myopathy is very relatable to human Takotsubo Cardiomyopathy, and thus this paper will aim to trace how animals are very relatable to humans even through the Cardiovascular System based on normal physiology and stress. (WHAT SHOULD I TALK ABOUT?)
Tokgozoglu, L. S., Ashizawa, T., Pacifico, A., Armstrong, R. M., Epstein, H. F., Zoghbi, W. A. Cardiac involvement in a large kindred with myotonic dystrophy: quantitative assessment and relation to size of CTG repeat expansion. JAMA 274: 813-819, 1995.
Congestive Heart Failure is when the heart's pumping power is weaker than normal. It does not mean the heart has stopped working. Blood moves through the heart and body at a slower rate, and pressure in the heart increases. This means the heart cannot pump enough oxygen and nutrients to meet the body's needs. The chambers of the heart respond by stretching to hold more blood to pump through the body, or by becoming more stiff and thickened.
[11] Nishimura, Rick A., Ommen, Steve R., Tajik, A.J., (2003) Hypertrophic Cardiomyopathy: A Patient Perspective. Dallas, TX: American Heart Association,
Congestive heart failure is a chronic state, often referred to as heart failure. Heart failure occurs when the heart muscle does not pump blood as well as it should. There are various complications with congestive heart failure. For example, narrowing arteries in the heart, known as coronary artery disease or high blood pressure, repeatedly leave the heart too weak or stiff to fill and pump successfully. Sadly, not all situations that lead to heart failure are reversible, but treatments are implemented to improve the symptoms of heart failure and provide a longer lifestyle. Day-to-day lifestyle changes such as exercising, reducing salt, managing stress, and losing weight can improve the quality of life. Additionally, a patient taking a combination
There are three main types of disease that cause cardiomegaly. The main type is dilated cardiomyopathy. This is when the walls of both the right and left ventricles become thin and stretched. Hypertrophy cardiomyopathy is when the hearts left ventricle becomes abnormally thick as a result of high blood pressure and hypertrophic cardiomyopathy is a result of an inherited condition.
This condition can be treated various ways depending on “the type and frequency of arrhythmias, associated symptoms…, and the presence of structural heart disease” (Cleveland Clinic, 2014). Some patients may not need treatment at all, since they show not symptoms, since sometimes this condition can be naturally eliminated over the first year of life, but may still be required to have regular schedule appointments with the physician so the patients can be monitored. If symptoms are prevalent, the different treatment methods include a pacemaker, defibrillator, surgery, and medicine.
How Do Economic Factors and Heart Disease Rates Relate in the New York Metropolitan Area?
Kremastinos, D. T., Farmakis, D., Aessopos, A., Hahalis, G., Hamodraka, E., Tsiapras, D., et al. Beta-Thalassemia Cardiomyopathy. Circulation: Heart Failure, 3, 451-458. Retrieved May 18, 2014, from http://circheartfailure.ahajournals.org/content/3/3/451.full#ack-1
George Tanas Mina Younan 15 March 2016 English II honors. The Development of the Human Heart We all know many fascinating facts about the human heart, but we never stop to think about how it develops and how it came to be. Many organs develop during your conception period. One of those organs that developed during this stage was the heart.
Heart disease can refer to an assortment of diseases affecting the heart. A heart attack happens when a heart muscle is destroyed or hurt due to not getting enough oxygenated blood to maintain life. Different examples of Heart Disease include Cardiomyopathy, Cardiovascular Disease, Hypertension, and Ischemic Heart Disease. Pediatric Heart Information for Patients, Families, Medical Professionals – Information on different. heart conditions and diseases in children.