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Principles of ethics in biomedical research
Principles of ethics in biomedical research
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Recommended: Principles of ethics in biomedical research
What are the criteria for judging whether research is worthwhile? Is there some research that should not even be done?
Depending on one’s outlook, there can be multiple goals and reasons for
conducting research. These reasons can be as simple as expanding a field of knowledge
for knowledge’s sake alone: "scientia gratis scientiae" in Latin or more noble causes such
as evaluating cures for fatal diseases, alleviating poverty, reducing crime rates or
enhancing educational methods. Regardless of the purpose, certain research guidelines
must be followed.
When considering any research involving human subjects, it is first important to
follow the basic ethical principals outlined in the Belmont Report (Bachman & Schutt,
2011). Those principals being respect for human subjects, informing them of any risks or
rewards (justice) and minimizing those possible harms (beneficence) and also includes
informed consent. If studies do not conform to these basic principals, an extremely
strong case could be made they should not be conducted. The text cited Zimbardo’s
Stanford Prison Experiment as a glaring example of unethical research (Bachman &
Schutt, 2011).
It was ironic this past week’s New York Times Magazine had an interview with
Dr. Zimbardo, based on the upcoming movie ‘The Stanford Prison Experiment”.
This is the link to his brief interview:
http://www.nytimes.com/2015/07/19/magazine/philip-zimbardo-thinks-we-all-can-be-evil.html
What is the most effective model of the research process?
There is no one most effective model for every research process; a one-size fits all
approach is not the best choice. Each research question must be evaluated independently,
to ascertain the best fit and meth...
... middle of paper ...
...d they are discussing validity. In
order to evaluate research the following questions should be considered:
1. What is the research question being posed?
2. Does the research question match the research design being used?
3. How was the study conducted?
4. What are the results of the study? Was the data collection accurate? Was it analyzed properly?
5. Are there other explanations for the study results, aside from those posited by the researcher? Could those (confounding) variables pose a threat to the study validity?
To summarize, good research requires some framework, some general guiding principles
to sustain it and evaluate it. Without these principles, it may be nothing more than a
collection of random observations, narratives, measurements or guesses at information
and its significance to science or the human condition.
Research is a systematic inquiry that uses disciplined methods to answer questions and solve problems. The ultimate goal of research is to gain knowledge that would be useful to many people. The Tuskegee study was initially started to study the effects of untreated Syphilis for about six to nine months, followed by treatment phase which gained public interest and outcry from public which led to actions initiated by US federal. The knowledge and information gathered from the study was very small compared to the risk that the men and their family endured. The participants and the families got compensated after a lawsuit was filed, but the physical, emotional and mental damaged caused cannot be
The second completed pilot study was conducted in Solothurn, Switzerland. The final analysis was completed in January 2011.
Describe the differences in the results between the groups in the study and support your description with examples from the study
...the data did not involve member checking thus reducing its robustness and enable to exclude researcher’s bias. Although a constant comparative method was evident in the discussion which improved the plausibility of the final findings. Themes identified were well corroborated but not declared was anytime a point of theoretical saturation Thus, the published report was found to be particularly strong in the area of believability and dependability; less strong in the area of transferability; and is weak in the area of credibility and confirmability, although, editorial limitations can be a barrier in providing a detailed account (Craig & Smyth, 2007; Ryan, Coughlan, & Cronin, 2007).
The article cites very little of the actual facts of the study making the claims harder to accept and more susceptible to critique. The study itself seems to have overlooked some added external effects and made some assumptions critical to the issue. One factor discussed in class is the size of the study and the people comprising the study. The study size is a decent study size of 37,000. However, the study does not specify some serious factors, such as family size, the structure of the family, the age of the participants and how long the study followed children.
The pretest-posttest design, crossover design, placebo, quasi-experiments (lack randomization but involve intervention and is usually found to be more acceptable to a broader group of people who are not always willing to be randomized in clinical trials). The RCT study known as the “gold standard” (for interventional studies, controlled and randomized for comparing a controlled and interventional group variable) and The Cohort (prospective) design research (analysis or the observational design with cohort, it starts with a recognized cause and then goes forward to the recognized effect). The clarification of the outcomes of the statistical analysis in quantitative research, understanding the research practice and the identification of the basis of evidence-based practice contained by the sections of research and critiques of that research. By graining an understanding of these steps and knowing how to rethink research and revise my views of the research will aid in success of my practicing these tactics (Polit, & Beck,
In this day and age anyone can write anything and put it on the internet for everyone to read. You have to be diligent in separating fact from fiction. If you are skeptical you may have to do your own research to see where the information originated. Do not believe everything you read just because it states it was from a study as it may not be reliable or truthful. Both of these studies had interesting information, however since they both were lacking sufficient data it was hard to determine if the studies were completely honest and adequate or not.
There was a study in 2009 by U. S. Department of Health and Human Studies which was
Models can be tested, changed, or used to guide research or to provide a base for evaluation(Blais,2002).
10). Other characteristics include a focus on the objective and quantifiable, emphasis on specific concepts, the researcher is an external, large sample, measured information, and includes statistical analysis (Polit & Beck, 2017). The use of quantitative methodology fits this study’s purpose because it asks specific questions about how frequently the phenomenon occurs, what factors are related to the stated phenomenon, and what is the underlying cause (Polit & Beck, 2017). It also asks what would happen if the phenomenon was altered, and can the occurrence be prevented (Polit & Beck,
order to make an informed decision about the value of the research. Further, it will be argued
Planning or conducting a study requires research and a good design. “A good design, one in which the components work harmoniously together, promoting efficient and successful functioning; a flawed design leads to poor operation or failure” (Maxwell, 2013, p. 2). When conducting research, the research questions are the normal starting point. They are what drives the study and, therefore, the piece that controls the design which all other components must follow (Maxwell, 2013). With the research questions at the center of the design, unlike typical research models, the interactive model of research design is connected in such a way as to provide
The researcher has to revise the action plan if the results are far deviating and ambiguous in nature. This will help to omit the invalid assumptions, logic and wrong procedures followed in the earlier steps. The revised plan has to be put in action and further develop a strong understanding befo...
The Importance and Appropriateness of Utilizing Different Methodologies for Research. Introduction The process of research entails the logical as well as systematic search for useful data and information with regard to a specific topic (Jha, 2008). It is also comprised of the investigation of the best, most cost effective and appropriate solutions to both social and scientific issues, following an objective and logical analysis. Jha, (2008) defines research as the search for knowledge and the discovery of the truth. During this process, the data can be gathered from a wide pool of sources among them interviews, books, nature among others.The data can then be analyzed with the appropriate data analysis tools, so as to report the findings