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Importance of crispr
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The sequences of CRISPR were first discovered in 1987, when scientists reading genetic code found five identical segments of DNA separated by bits of DNA that match that of a virus. CRISPR, which is a specialized strand of DNA, stands for clustered regularly interspaced short palindromic repeats. It can be used as a defense system to “cut out” and destroy virus DNA and unwanted genes. It is the most powerful genetic engineering technology ever discovered, and harnessing and using it could have both powerful benefits and dire consequences.
The biggest pro of CRISPR is its function- the fact that it can be used to cut out any bad gene that it is “told to.” One way it could potentially help people is by protecting against Alzheimer’s disease by cutting out the gene that increases the risk of contracting Alzheimer’s and replacing it with a protective gene, the likes of which are found naturally in some. In trials, CRISPR was used to increase the strength of mice with muscular dystrophy. Muscular dystrophy is thus far incurable, but being able to increase the strength of
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It could cause a permanent change in generations to come in whatever organism receives the new gene. If you enhance the DNA of an animal, you run the risk of overpopulation, that animal becoming toxic to another, or changing their environment in another, unforeseeable way. The other concern, mainly regarding using CRISPR in human beings and embryos is the dilemma of crossing an “ethical line.” Embryos and future generation can’t consent to being genetically altered. CRISPR could potentially be used to create a “designer baby,” which is an embryo that has been genetically altered to produce desirable, even superior, traits. Some consider this unethical, and that it would be getting rid of natural diversity. This process of gene editing could be used to make people wealthy, instead of keeping it available for
Gene editing will also take away the uniqueness of a baby. Due to them being modified babies they will have more of an advantage over the other normal kids which will not be fair to the others. This will more than likely turn into a competition. This will cause a world class of separation causing it to be a gap in society. For example, in schools there may be certain classes in which the normal kids attend. Due to them being the normal kids they get treated as if they know little as nothing and shown very little attention. Then there will be classes in which the
...e the quality of life of children. A big consequence to the use of genetic modification, shown in the movie Gattaca, is the prejudice that can be against those without genetic modifications. To create an idea of what the consequences of genetic modification will look like, a real world example would be racism and the use of eugenics to justify the prejudice against those who were not light-skinned or of caucasian descent. Neo eugenics is a very controversial topic that has a lot of possible benefits and consequences and will affect many generations to come.
Crispr is now being used in a variety of ways, one of which include using ...
Scientists examining the immune system of bacteria discovered a molecule that presented a cure to all genetic diseases. This molecule, called CRISPR/Cas9 (referred to as CRISPR), is essentially a highly precise “pair of molecular scissors” that “snip” at any point “in the cell’s DNA”, guided by a small, highly “customized guide molecule” made of RNA (Lanphier).By including “a new piece of DNA” with the injected CRISPR, genes can be corrected or even added to the existing genome. CRISPR can also repair molecular defects with expression mechanisms, and is capable of changing the way of how a gene is expressed (Lanphier). It is clear that CRISPR is a powerful scientific tool that has the potential to change the use and outlook of genetic engineering
Human beings are not born perfect, there are sometimes imperfections that one would not be able to fix. If an adult has a disease that is passed down from their genes, there is a high possibility that the child would get it. The ability to pick specific genes for their child is astonishing. With the CRISPR technology, one is able to create their version of a perfect baby with genes that they prefer. In many perspectives, their discovery will save a lot of families worries, making their life better, especially at the point where their lives is going to be better.
Sorry for my delay in getting back to you and your question. I think patenting the CRISPR technology could be very troubling. In a recent article I found that a patent already exists regarding the CRISPR technology and its specific use with eukaryotic cells, but that UC Berkeley lost their patent request for a broader usage. What’s dangerous about this is that anyone who holds the patent also holds the rights to the reproduction of the technology. This means money for the patent holder (Netburn, 2017). They could sell the technology to the highest bidder and not necessarily to a scientific or altruistic organization. Following this impact, it could mean someone could own the technology to edit genes and make cosmetic alterations in humans such
As medical technology and research advances, society’s once limited knowledge of the causes of diseases and disorders is growing. Along with this new information comes new methods of curing and at times, completely eliminating these diseases from the body. A new form of this is CRISPR-Cas 9 gene editing. According to the Your Genome article, “What is CRISPR-Cas9?,” CRISPR-Cas 9 is a “technology that enables geneticists and medical researchers to edit parts of the genome by removing, adding, or altering sections of the DNA sequence” (“What is CRISPR-Cas 9?” para. 2). In other words, the enzyme, Cas-9, is able to go into a person’s DNA and change parts of it, completely changing a person, in either terms of physical attributes or diseases in
Recently, MIT Technology Review’s editor published an article about the future of GMO. To provide some context, GMOs are genetically modified organisms that are artificially altered using a process known as recombinant DNA technology. GMOs have faced a lot of controversy, mainly regarding the health implications of GMOs. Currently, plant scientists and startups have avoided creating new genetically modified crops, due to the large costs and long approval times for new crop modifications. As a result, large agricultural and chemical producers, such as Monsanto control basically the entire GMO market and turn it into a very lucrative business. The outcome of this situation is a scary amount of dependency on a handful of profit-oriented companies that genetically modify seeds to maximize profits, rather than to improve the well-being of the consumer.
Many scientists and innovators alike are asking “What would it be like to have a baby? Or even a baby that you designed? This baby having no diseases and to cure your diseases in addition, all with the same process.” Well this can all be yours with the likely unavoidable side effects of this DNA cutting and insertion. Although, while this new and groundbreaking technology, known as CRISPR/Cas has only been used widely for three years. During, this short span of wide use it has gained overwhelming traction and controversy. The audience that this technology draws can be strongly attributed to this topic’s controversial core and its possibilities for the future.
When it comes to Genetically Modified Organisms, I have a neutral point of view. I see the negative outcomes of it but I also see the way it can benefit the whole world. Genetically Modified Organisms means that we are messing with nature and how it naturally works. This, on the long run, can cause many effects on humans. Genetically modifying food can lead to us having some mutation in our DNA just because we are eating foods that were modified. There are many people out there looking for organic food because they believe that the food now have to many chemicals and hormones. Small farmers can no longer make a living because they are competing with large companies that can make twice as much goods as they can in half the amount of time. On the other hand, these foods are more resistant to parasites, they grow faster, and they have higher yield of proteins in them. The ability to grow more food faster and without parasites means that there will be more people on the earth with food. There are too many people living on different parts of the world that do not have enough food to
CRISPR is a natural occurring process whose purpose is to act as a defense mechanism fighting off viruses in prokaryotic organisms. Scientist, however, have figured out a way to emulate this same process. First by creating a piece of RNA who matches part of a desired gene which they intend destroy, then the RNA is bonded to a Cas9 and sent through the nucleus, next the RNA is binded to the DNA to where it signals Cas9 to the strands, and finally the cell miserably fails to correct the cut, but along the way it accidentally adds a few nucleotides which shuts the gene down. Cas9 plays a vital role in this process since Its a protein in charge of locating and severing target DNA. The protein is split into six domains and the largest one is responsible
CRISPR has been experimented mostly on animal embryos except for the case of the procedure that took place in China. What people worry about the most is the fear that CRISPR will be used to modify the human germ-line since it can precisely edit genes for targeted traits “which can be passed down to future generations”(The Conversation). The idea of this occurring sparks back the idea of the eugenics movement which occurred in the early 1900’s where the idea of creating the perfect race was in motion. During this time, “the eugenics movement in the US quickly focused on eliminating negative and undesirable traits” (Nature). The Eugenics movement that was evidently a “tragic time in our country’s history” (Nature) and CRISPR is the match that has sparked up the issue of creating the perfect race once
The technology known as CRISPR, involves a protein called Cas9 that targets a section of DNA and with an enzyme called nuclease, it can cut unwanted genes out and put new ones in. CRISPR allows a simple way to edit DNA with speed and precision. When using CRISPR to edit somatic cells, specific types of cells are being modified,
We are all different in many ways. It’s normal and that is what makes us all unique. Though sometimes, it can cause a lot of pain and suffering. But now in the twenty first century, we can make ourselves perfect. Geneticist Jennifer Doudna co-invented a groundbreaking new technology for editing genes, called CRISPR-Cas9. The tool allows scientists to make precise edits to DNA strands, which could lead to treatments for genetic diseases . Genetic illnesses such as Down Syndrome, and Cystic Fibrosis have no cures or medication. With this new tool, doctors will find a cure that is bound to succeed. It works by injecting a protein into the body where it is absorbed into a cell. From there, it gets into the nucleus where the genetic information is held. If there is an error in the DNA sequence, the CRISPR technology will make a precise cut at the error and will replace it with a new one. After this, the DNA will automatically repair itself and the rest of the cells into the body until the person is fully cured. According to a MIT technology
Gene therapy is an experimental technique that uses genes to treat or prevent disease. Currently, there are a lot of studies and experiments that allow doctors to treat a disorder by inserting a gene into a patient’s cells instead of using drugs or direct surgery. Researchers are testing several approaches to gene therapy, such as replacing a mutated gene that causes disease with a healthy copy of the gene, inactivating, or “knocking out,” a mutated gene that is functioning improperly, introducing a new gene into the body to help fight a disease, and helping to regenerate precious cells. Although gene therapy has a very active and promising approach for a number of disease, there are still several risks and side effects. Hence, the therapy