Syphilis Essay

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Syphilis is a sexually transmitting infection caused by Treonema pallidum, a gram negative, and anaerobic spirochete bacteria 1. Syphilis is thought to have been brought to Europe by Columbus and his sailors in the 1500’s 1. The disease is characterized by four different stages with varying symptoms depending on the stage that the disease is in1. Often syphilis is presented with another sexually transmitted infection such as chlamydia. Public education regarding safe sex is important for the prevention of this sexually transmitted infection.
T. pallidum is highly sensitive to oxygen and has a decreased ability to survive when not in human body temperature environments 1. The mode of transmission is through sexual contact or vertical transmission from the mother to the fetus. T. pallidum lacks the lipopolysaccharide which is the endotoxin normally present in gram negative bacteria1. The bacterium does produce many lipoproteins which are thought to prompt the inflammatory mediators through the recognition of toll-like receptors1. T. pallidum has a virulence factor of being highly motile due to its ability to propel itself forward by rotating on a longitudinal axis1. The spirochetes easily penetrate the skin or mucosal membranes and spread throughout the lymph nodes and then the blood circulation, affecting many parts in the body1.
The primary stage of the infection is characterized by a chancer that presents as an ulcer in the anogenital area with an incubation period of nine-ninety days2. A chancer is a painless ulceration that forms where the original spirochete enters the broken skin or mucous membranes3. The lesions can also present on the lips, tongue, tonsils and nipples2. During the incubation period the T. pallidum can ...

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...allergic to penicillin3. All individuals with a positive laboratory result for Syphilis and the sexual partners of those infected are treated3. Safe sex education, increasing public awareness and partner tracking of the infected individuals are being implemented to reduce the occurrence of Syphilis. A patient with syphilis should be taught to avoid sexual contact until they have finished their antibiotic therapy to prevent transmitting the infection to others 4. Patients should also be taught the importance of notifying all recent previous sexual partners so that they can be tested and be treated if necessary4. It may be embarrassing for infected individual, but the health care provider needs to stress the importance of disclosing the information to their sexual partners. All cases of syphilis cases need to be reported to the public health authorities4.

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