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James Watson and his contribution to DNA
Essay watson and crick dna
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DNA, it makes everyone special and unique. Throughout time, scientists have discovered many facts about DNA. One such discovery was the pairing of adenine-thymine and guanine-cytosine, but what about the structure? Watson and Crick are acknowledged the most for discovering and contributing the most to the structure of DNA in eighteen months; but what about Franklin? Though Watson and Crick are known for discovering DNA’s structure, Rosalind Franklin contributed the most to finding the structure of DNA because she was the first to take pictures of DNA’s B form, discover phosphate on is on the outside of DNA, and debunk DNA is antiparallel.
First, Franklin took a picture of DNA’s B form. That photo was acquired through Franklin bundling super thin strands of DNA and zapping them with a super fine x-ray beam. Through the photo is showen a fuzzy cross which meant DNA had a double helix. The double helix was a major
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She discovered phosphates are on the outside of the DNA strands. The phosphates are on the outside so that the phosphate-phosphate interhelical bonds are disrupted by water. Also, the hydrophilic phosphates caused the molecule to soak up water and lengthen causing the wet DNA to produce a sharp diffraction picture that resembled the pattern of a x; further proving phosphates are on the outside. Through Franklin’s research, phosphates were discovered to be on the outside of DNA strands which allowed other information to be put in place; such as nitrogenous bases and sugar. It helped show that each nucleotide includes one nitrogenous base, attached to the 1’ carbon of the sugar, then the sugar is attached to 5’ of the phosphate. Franklin opened a passageway for Watson and Crick to further more their own discovery. In addition to finding phosphates are placed on the outside of DNA strands; Franklin also discovered DNA is
Francis Crick: He does the same research with Watson and they are both teammates. He is also eager to know what is in DNA and the relationship of it with the double-helix, but at the same time is disorganised, and expected Watson to do a majority of work.
Ted Bieler’s Helix of Life (1971) that is located outside the Medical Sciences building at University of Toronto is a sculpture made from a light grey concrete material. Its color appears to be plain which happens to match the exterior of the Medical Sciences building as well. Due to the age of the sculpture, it shows lighter and darker gray dents and streaks near the top and bottom and where it bends. Some of the markings have been made from the material and texture of the sculpture. The material used, which was said previously, is cast concrete. Using concrete without any smooth surface tools creates a rougher and coarse texture which is why it has dents and holes when viewing it up close. As the viewer looks at the sculpture from afar, its
In this case, the reward for winning the “competition” is so significant that better opportunities are overlooked and some are left without the aid they need. When Watson and Crick ask Rosalind Franklin’s opinion on their model of DNA, the result they are looking for is far from what they had hoped: “Rosy did not give a hoot about the priority of...
Benjamin Franklin has been without a doubt one of the most relevant individuals in US history. His autobiography gives us a brief but detailed summary of what his life was like and how society worked in the eighteen century. This autobiography gives us many details of how the colonies where and offers and an overall image of the development of British North America which later turned into the United States. Due to the fact that this book was originally written for Franklin's son, the book concentrates in personal information and has very little information about other topics. However, there are some topics that can be extracted from his writings; one of them is gender. Even though, Franklin never talks openly about gender, we can observe how in his writing these roles are clearly assigned. In this paper, we will analyze how Benjamin's Franklin autobiography showcases the importance of gender in the early eighteenth century. Gender can be analyzed in Franklins book by looking at different topics. This given to men and women by society can be seen in the workspace, in the education of each individual, and in the family and family structure.
African or black history was not a study that was done by many until the last century. Studying African Americans accurately as part of American History was an even newer field of history. John Hope Franklin’s obituary calls him, “the scholar who helped create the field of African-American history and dominated it for nearly six decades.” He would call himself an historian of the American South.
The book Rosalind Franklin and DNA is a biography of Rosalind Franklin written by a British journalist and close friend of hers, Anne Sayre to reveal the true personality of Rosalind Franklin in contradiction to the fallacious character portrayed by James Watson in his personal account of The Double Helix. This book was undertaken to refute Franklin’s distorted portrait from abnormal feminist into rational, perfectionist and talented ‘women’ scientist. She begins by introducing her strong background, curious childhood, dedicated education, generous nature and most importantly how she was brought up in a favorable environment of distinctive Angelo-Jewish family, who identified and cultivated her talents and developed her in a person with full capacity for commitment. In this book, despite admiring the geniuses of Watson in depicting and picking out small information, connecting points and the kind of abilities he possessed was perfectly factitive with Crick that Rosalind and Gosling lacked however, she constantly tries to put the Rosalind’s side of story in picture which she believes was minimized in The Double Helix by Watson and correct her character that distorted in public eye.
The molecule consisted of a double helix with phosphates, deoxyribose sugar molecules, and nitrogenous bases. If the spirals were split, the DNA could replicate, which explained why genes were transferred from parents to their children. Additionally, the order of compounds on the DNA indicated that there was a unique ‘code’ on each strand. Watson and Crick believed that this ‘code’ was translated into specific proteins. , ,
In his many careers as a printer, moralist, essayist, civic leader, scientist, inventor, statesman, diplomat, and philosopher, for later generations of Americans he became both a spokesman and a model for the national character. He was born in Boston, Massachusetts on Jan. 17, 1706, into a religious Puritan household. His father, Josiah, was a candlemaker and a skillful mechanic. His mother, Abiah Ben’s parents raised thirteen children--the survivors of Josiah’s seventeen children by two wives (#1).
The Autobiography of Benjamin Franklin is a representation of the new prospect of upward mobility in colonial America during the 18th century and the development of the Age of Reason, which assisted in the conception of the idea of the “American Dream”; a dream that includes fundamentally social ideals such as democracy, equality, and material prosperity. Furthermore, Franklin’s autobiography exemplifies a significant shift in focus from religion to enlightenment and reason. Additionally, there were forces specific to Benjamin Franklin's Philadelphia, that played an important role in his perspectives and the changes that occurred within colonial America during the 18th century.
In Benjamin Franklin’s The Autobiography, he ornately and distinctly portrays each of the characteristics of the enlightenment. First characteristic of enlightenment Franklin presents is perfectibility and progress, a belief that one has the ability to improve and change. Whilst, Franklin was working on his list of virtues to improve himself to accomplish his goals, he came to add the thirteenth virtue as one of his Quaker acquaintance confessed about him, “But a Quaker friend having kindly inform’d me that I was generally thought proud; that my Pride show’d itself frequently in Conversation” (Franklin 530). After being informed, Franklin immediately convinced himself to improve his pride by adding one more virtue in his list “Humility”. In
Benjamin Franklin was born on January 17, 1706 in Boston Massachusetts. He was one of seventeen other brothers and sisters. His father, Josiah Franklin, who emigrated from Oxfordshire, England, worked as a soap boiler and tallow chandler. Benjamin’s mother, Abiah Folger, was from Nantucket but her family derived from England as well.
"The discovery of the structure by Crick and Watson, with all its biological implications, has been one of the major scientific events of this century." (Bragg, The Double Helix, p1) In the story of The Double Helix, James Watson tells of the road that led to the discovery of life's basic building block-DNA. This autobiography gives insight into science and the workings within a professional research laboratory that few members of society will ever be able to experience. It also gives the reader an idea of the reality of life for one scientist and how he struggled with the problem of DNA. However, the author's style is marked by his lack of objectivity and inclusion of many biased opinions and personal prejudices.
DNA (deoxyribonucleic acid) is a self-replicating molecule or material present in nearly all living organisms as the main constituent in chromosomes. It encodes the genetic instructions used in the development and functioning of all known living organisms and many viruses. Simply put, DNA contains the instructions needed for an organism to develop, survive and reproduce. The discovery and use of DNA has seen many changes and made great progress over many years. James Watson was a pioneer molecular biologist who is credited, along with Francis Crick and Maurice Wilkins, with discovering the double helix structure of the DNA molecule. The three won the Nobel Prize in Medicine in 1962 for their work (Bagley, 2013). Scientist use the term “double helix” to describe DNA’s winding, two-stranded chemical structure. This shape looks much like a twisted ladder and gives the DNA the power to pass along biological instructions with great precision.
The Double Helix tells a tale of fierce competition, perseverance, and scientific innovation as we follow James Watson and his cohort Francis Crick on their quest to discover the secret to life, the structure of deoxyribonucleic acid. Although already fascinated with DNA, Watson struggled with finding chemistry exciting enough to learn it in depth. He had studied birds in college and thereby managed to avoid any formal chemistry or physics courses. As he later pursued a PhD in biochemistry, he realized he could put it off no longer and attempted to learn organic chemistry at Indiana University. However, after a mishap in the lab, he was encouraged instead to study nucleic acid chemistry with Herman Kalckar in Copenhagen. There, his mind strayed from his work and he began doing unauthorized research in the lab of Ole Maaløe, studying phages. Herman stopped teaching Watson after going through a divorce with his wife, and sent Watson off to a scientific conference in Naples. Although he was bored by many of the lectures, Maurice Wilkins’s talk about X-ray diffraction fascinated Watson. He was struck by an X-ray diffraction picture of DNA that Maurice presented and was determined to study the acid. He later got to know more about Maurice’s colleague, Rosalind Franklin, who was proud, stubborn, and very difficult to work with. Watson greatly admired the lecture given by the renowned Linus Pauling, who had discovered the structure of the alpha-helix and was thought of as the leader in DNA research in the scientific world.
...f the structure of DNA by James Watson and Francis Crick in 1953 that was extremely influential for future researchers. They determined that DNA was a double helix structure composed of base pairings, with a sugar phosphate backbone. This model explained how “genes can duplicate themselves [and] would eventually lead to our current understanding of many things, from genetic disease to genetic engineering” (Salem).