Ototoxic Medication to Treat Hearing Loss

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SUMMATIVE ASSESSMENT

Question 1.

1. Bilateral Symmetrical Normal-Moderate Sloping Sensorneural Hearing Loss

2. It is Ototixicity, the site of lesion is within the inner ear in the cochlea hair cells. Mr T is currently taking medication for Multi Drug-Resistant TB, many TB medication are ototoxic( side effect of hearing loss ear and / or tinnitus) to the hearing (Cristobal & Oghalai, 2008; Da Costa, Rosito & Dornelles, 2009; Munro & Blount, 2009; Schreiber, Agrup, Haskard & Luxon, 2010). The MDR-TB medication is ototoxic therefore the medication causes functional impairment and cellular generation to the tissues of the inner ear, and especially of the end-organs and neurons of the cochlear and vestibular divisions of the eight cranial nerve (Munro & Blount, 2009; Schreiber, Agrup, Haskard & Luxon, 2010). The damages to these structures affects auditory and balance system which results to hearing loss, tinnitus (ringing in the ear) and dizziness (Cristobal & Oghalai, 2008; Da Costa, Rosito & Dornelles, 2009; Munro & Blount, 2009; Schreiber, Agrup, Haskard & Luxon, 2010). The medication contains aminoglycosides compounds; amoniglycosides cause loss to the hair cells of the organ of corti (Cristobal & Oghalai, 2008; Da Costa, Rosito & Dornelles, 2009; Munro & Blount, 2009; Schreiber, Agrup, Haskard & Luxon, 2010). When it is most severe, the basal turn of the cochlea and is progressively less towards the apex. The inner row of the outer hair cells is affected, then followed by the outer row, then later on to the rest of the organ (Cristobal & Oghalai, 2008; Da Costa, Rosito & Dornelles, 2009; Munro & Blount, 2009; Schreiber, Agrup, Haskard & Luxon, 2010).

3. the patient must be prescribed/recommended to a medication that is les...

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.... P. (2010). Wideband acoustic-reflex test in a test battery to predict middle-ear dysfunction. Hearing research, 263(1), 52-65.

Munro, K. J., & Blount, J. (2009). Adaptive plasticity in brainstem of adult listeners following earplug-induced deprivation. The Journal of the Acoustical Society of America, 126(2), 568-571.

Schreiber, B. E., Agrup, C., Haskard, D. O., & Luxon, L. M. (2010). Sudden sensorineural hearing loss. The Lancet, 375(9721), 1203-1211.

Sliwinska-Kowalska, M., & Davis, A. (2012). Noise-induced hearing loss. Noise & health, 14(61).

Thorne, P. R., Ameratunga, S. N., Stewart, J., Reid, N., Williams, W., Purdy, S. C., ... & Wallaart, J. (2008). Epidemiology of noise-induced hearing loss in New Zealand. NZ Med J, 121.

(Cristobal & Oghalai, 2008; Da Costa, Rosito & Dornelles, 2009; Munro & Blount, 2009; Schreiber, Agrup, Haskard & Luxon, 2010)

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