Membranes: The Fluid Mosaic Model In Biomembranes

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1. Introduction

Biomembranes are essential to every living form of life know, from bacteria to human beings. To begin with, they mark the boundaries of cells, therefore making us able to tell where does a living being start and end. There are membranes that fulfill extremely complex tasks, for example generating energy for the cell, for which membranes play a key role in creating the gradient that is required.

These membranes contain lipids, proteins and carbohydrates. Of those, the ones that actually form the membrane and are absolutely fundamental are lipids. The most common lipids in biomembranes are phospholipids, sphingolipids and sterols. Proteins can be either integral, which means that the have at least one transmembrane segment, or peripheral, that can be attached to the membrane in many different ways.

Lipids and proteins determine the permeability of the membrane, and consequently what gets in and out the cell. Hydrophobic molecules can pass through thanks to the non-polar moieties of lipids that make the …show more content…

One of them is the presence of highly specialized domains in biomembranes, the so called “lipid rafts”. This domains are rich in proteins and, regarding the lipid composition, have a higher proportion of sphingolipids and cholesterol. They are also the usual location of the glycosylphophatidylinositol anchored proteins. They can also be formed and dissolved in the membrane depending on the needs of the cell. This is the main reason for that their existence is not completely accepted yet, even thought many evidences have been presented over the years.

Nevertheless, the Fluid Mosaic Model still lacks many details. A better understanding of the details of organization in the membranes, mobility between leaflets and many more would be described, in the years to come, along with their consequences, fulfilling our knowledge about biological

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