In Vitro Frtilization By Robert G. Edwards

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Thousands of babies are born each year to couples who may have never been able to conceive on their own. Dr. Robert G. Edwards is given the credit for developing a procedure called in vitro fertilization, which continues to give hope to couples all over the world. The term “in vitro,” broken down, implies that a process occurs outside of a living organism, therefore “in vitro fertilization” simply means fertilization outside of an organism. This groundbreaking accomplishment is what lead Dr. Edwards to being awarded the 2010 Nobel Prize in Physiology or Medicine. While previous studies had been done on the subject, he was the first to conduct the research necessary to make in vitro fertilization truly possible, and with help from Patrick Steptoe, …show more content…

Robert G. Edwards’ beginning stages of his years of research. Dr. Edwards’ began his research in the late 1950s, and his first obstacle was access to oocytes that were at the correct stage for in vitro fertilization. It was not until 1965 that he discovered human oocytes, “required 24 hours of incubation in vitro, before they would initiate their maturation process” (Nobelprize.org 4). Next, he had to find conditions that would encourage the fertilization of oocytes. He used the buffer conditions identified by Barr D. Bavister to activate human spermatozoa and fertilize in vitro oocytes in 1969, however the fertilized oocytes were not progressing beyond the second stage, which lead him to try to use oocytes that completed their maturation process inside the body. Laparoscopy was a new method at the time, and it allowed surgeons to remove oocytes at the appropriate stage of development. Laparoscopy is a procedure where a lighted tube is inserted through the abdomen, requiring only a small incision (WebMD 1). In 1971, this discovery, with the help of his colleague, Patrick Steptoe, allowed for advancements to the development of 8-cell stage embryos, and later 16-cell stage and blastocysts (Nobelprize.org 6,7). The final error that called for correction was the hormone treatments women were receiving to induce oocyte maturation, which they decided to stop the use of this method entirely. These hormone treatments were resulting in spontaneous abortions. Once this final issue was solved, Louise Joy Brown was born - the first baby successfully born through the method of in vitro fertilization. July 25, 1978 was the date of this incredible

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