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Giardia lamblia eluiga
Giardia lamblia eluiga
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Giardiasis is a disease of the lower digestive system caused by the parasite Giardia lamblia which is transmitted via a faecal-oral route. The infection is acquired when a person ingests a dormant cyst of the parasite, usually by drinking contaminated water. The disease affects around 200 million people worldwide and is especially prevalent in third world countries, where there are larger populations of people in areas with poorer sanitation and therefore a greater risk of the parasite being passed on from person to person through direct contact. However, the parasite is also zoonotic and may spread between animals and humans. After an incubation period of one to two weeks, symptoms such as severe diarrhoea, abdominal cramping, vomiting and weight loss may arise but some infected people remain asymptomatic and a carrier of the parasite. There are two assemblages of the causative agent Giardia lamblia which infects humans and other animals, except rodents. This parasite has a …show more content…
Outside of the host, Giardia lamblia is an infectious but dormant cyst, which protects the parasite. This form ensures the parasites survival in harsh and variable environments which are unfavourable for the colonization and replication of the parasite. The cyst exits the host in the excreted faeces and is resistant to harsh temperature and chemicals, as it has a very strong two layered cyst wall composed of sturdy inter-chain carbohydrate (galactosamine) interactions with proteins attached. The wall of the cyst is insoluble which means the Giardia lamblia can survive in water and be transmitted easily to other hosts via a faecal-oral route. Astonishingly, as few as ten cysts are needed to cause giardiasis. This infection of other hosts then leads to more cyst production, release and eventually an increase in the number of potential waterborne parasites in the
Bordetella pertussis is a highly communicable agent and is transmitted person-to-person via airborne droplets or direct contact with discharges from the respiratory mucous membranes of an infected person. This small, gram-negative coccobacillus is non-motile, aerobic and fastidious. B. pertussis colonizes the respiratory tract including the mouth, nose, throat and beginning of the lungs of young children worldwide. The bacteria bind to ciliated cells in the respiratory mucosa by producing adhesions. Filamentous hemagglutinin on the cell surface and pertussis toxin (Ptx) both help the bacteria in binding. Filamentous hemagglutinin binds to the galactose residues on the glycolipid of the ciliated cells. Ptx, in its cell-bound form, binds to the glycolipid lactosylceramide, which is also found on the ciliated cells. Ptx binds to the surface of phagocytes as well, causing phagocytosis of the bacteria. This mechanism may lead to enhanced survival as an intracellular parasite. Adding to its many purposes, Ptx deregulates the host cell adenylate cyclase activity. The A subunit of this AB toxin, affects the G protein responsible for inhibiting adenylate cyclase. This leads to an increase in cyclic adenosine monophosphate (cAMP) creating detrimental metabolic changes in the host cells.
Trabelsi, H., Dendana, F., Sellami, A., Sellami, H., Cheikhrouhou, F., Neji, S., … Ayadi, A. (2012). Pathogenic
Shigella flexneri, a facultative anaerobe belonging to the family Enterobacteriaceae, is a Gram-negative rod that is the causative agent of diarrhea and dysentery in humans. Potentially life-threatening, S. flexneri's effects include bacteremia, hemolytic uremic syndrome (HUS) and toxic megacolon (4). The principle disease of diarrhea and dysentery caused by this pathogen is known as shigellosis. 10-100 organisms are sufficient to cause disease, and transmission is generally from person-to-person by way of fecal-oral (2). Shigellosis can be characterized as a disease with over 60% incidence in children ages 1-5 (6).
Enterococcus faecalis is a genus of gram positive cocci and form short chains or are arranged in pairs. They are nonmotile, facultative anaerobic organisms and can survive in harsh conditions in nature. There are over 15 species of the Enterococcus genus but about 90% of clinical isolates are E. faecalis. E. faecalis is a nosocomial pathogen because it is commonly found in the hospital environment and can cause life-threatening infections in humans. It is a bacterium that normally inhabits the intestinal tract in humans and animals but when found in other body locations it can cause serious infections. The most common sites for E. faecalis infections are the heart, bloodstream, urinary tract, and skin wounds. Due to vancomycin-resistant Enterococci, many antibiotics have been shown ineffective in the treatment. In this paper, I will describe the ecology and pathology of E. faecalis; the antibacterial resistance; treatment; and, what you can do to prevent Enterococcus infection.
Treponema pallidum is a Gram-negative bacterium that has a spiral shape (1). They are about 6 to 20um in length and 18-20um in diameter (1). Treponema pallidum can only survive within a host which makes them obligate internal parasites, meaning that outside a host this organism will die due to the absence of nutrients, exposure to oxygen and heat. Also since this organism can’t be grown on a culture medium, animal models are used to study T. pallidum (1). Treponema pallidum bacteria consist of an inner and outer membrane with a thin peptidoglycan cell wall lacking liposaccharides (1). They have a distinctive corkscrew motility with the aid of 6 endoflagellas (2). The specific classifications of Treponema pallidum are the following: Scientific name- Treponema pallidum, Common name- Syphilis. Treponema causes syphilis, yaws, and spinta. Borrelia causes Lyme disease and relapsing fever and Leptospira causing leptospirosis (5). What makes this microorganism special to the human population is that it causes infection to its host by entering the body through microscopic skin or mucous abrasions via direct personal contact with the lesions (sexual or kissing), blood transfusions, accidental bacterial inoculation, and transplacental passage (2). According to the CDC website there are 55,400 people diagnosed with Syphilis every year and 322 reported cases of congenital Syphilis in 2012 (6).
Schistosomiasis is a parasite. This parasite is a worm that you get through contaminated water. Urine and feces usually contaminate the water. The worm goes in to your body and migrates to the bladder, rectum, liver, lungs, spleen, intestines and some veins. After the worm migrates to these places this is where it matures and lays its eggs. The disease has the ability to lay two thousand to three thousand eggs per day and can live for twenty years. There are five different kind of Schistosomiasis that effect humans, these different kinds are; S. mansoni, S. Heamatobium, S. japonicum, S. intercalatum and S. mekongi. There are also other kinds of Schistosomiasis that occasionally infect humans, there are; S. bovis, S. mathei, and some avian schistosomes.
Disease and parasitism play a pervasive role in all life. Many of these diseases start with microparasites, which are characterized by their ability to reproduce directly within an individual host. They are also characterized by their small size, short duration of infection, and the production of an immune response in infected and recovered individuals. Microparasites which damage hosts in the course of their association are recognized as pathogens. The level of the interaction and the extent of the resultant damage depends on both the virulence of the pathogen, as well as the host defenses. If the pathogen can overcome the host defenses, the host will be damaged and may not survive. If on the other hand the host defenses overcome the pathogen, the microparasite may fail to establish itself within the host and die.
Irregular bowel movements or constipation is quite a major and common concern in adults and babies as well. The condition becomes more challenging when it comes to babies. Parents of infants worry when their infant’s bowel movement is not regular and clear as that causes formation of gas and stomach pain.
Crohn’s disease is a disease that causes inflammation, swelling, and irritation to any part of the digestive tract which is also known as the gastrointestinal tract or GI tract. The disease most commonly targets the ileum which is a part in the small intestine. The digestive tract is organs that connect your mouth to your anus and it releases hormones and enzymes for the digestion in food. The inflammation caused by the disease goes deep into the lining of the digestive tract. It creates a stricture in the small intestine which is a narrowing of the pathway that can slow the movement of food through the intestine. The stricture can then move to large intestine which can cause many problems for absorption. When the disease causes the intestine to swell it can also be very problematic because the large intestine wouldn’t be able to function properly. Crohn’s disease is considered as an inflammatory bowel disease.
This disease may be on the brink of being eradicated entirely but that doesn’t stop it from being one of the grossest things that anyone has ever seen. The parasite enters the body via unsafe drinking water. When people drink water infected with water fleas that have have been hosting the larvae of the parasite. There are no symptoms, to begin with, but about one year later, blisters on the feet or legs begin to develop and then the adult fully developed worm crawls out of the host body over a period of a few weeks. It’s said that the pain is intense and can incapacitate a person for weeks at a time. The pain can also continue for months after the infection. The parasite needs to infect a person at least once a year in order to continue. There were an estimated 3.5 million cases in 1986 but the disease has been greatly reduced over time and only 22 cases were reported in 2015. This disease will probably be the first parasitic disease to be completely eradicated in humans.
The simplest explanation of the Salmonella infection is that a sufficient amount of salmonellae reach the small intestine and invade the lumen (the space within the intestine) where they mul...
No matter what, where, or who you are, water is a necessary component to keeping any organism alive. Although water is essential for life, in many places, clean drinking water is hard to find. There are many consequences to drinking contaminated water. Every year, three to five million people are attacked by water-borne diseases and over 100,000 of them die. One fatal disease that can kill within hours is cholera.
E. coli are bacteria that can cause an infection in various parts of your body, including your intestines. E. coli bacteria normally live in the intestines of people and animals. Most types of E. coli do not cause infections, but some produce a poison (toxin) that can cause diarrhea. Depending on the toxin, this can cause mild or severe diarrhea.
Urinary Tract Infection, also known as UTI, occurs in two common locations, the bladder and kidneys. The kidneys are important organs that aid in filtering out waste products from blood and maintaining water distribution throughout the body. The waste products are filtered out via bladder, which is the reason of the bladder being the second site for the infection. A normal human being has two kidneys, one on left and right side, a bean shaped organ, and is located at the back of the abdomen. “Each kidney is about 11.5 cm long, 5-7.5 cm broad, 5 cm thick, and weight about 150 grams” (HealthInfoNet, Paragraph 2). Furthermore, a bacterium named Escherichia coli lives in both the kidneys and the GI tract. E. coli is part of the human body and produces
Salmonella enterica typhi (typhoid fever causing bacteria) are parasites with no other known living environment outside of humans (Pike, 2014). Typhoid has the ability to cause large outbreaks and the Centers for Disease Control and Prevention (CDC) has classified Salmonella species with other food safety threats as high priority potential bioterrorism agents (Baggier, Burwen, Haber, & Ball, 2004). Salmonella enterica typhi is one of three species of the Salmonella genus. Typhoid gets its name from Typhos, which means smoke, or to cloud, or vapor. It was thought to be transmitted through a “cloud of sickness called miasma” (Pike, 2014). When someone recovers from typhoid fever, about 3-5% become carriers o...