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Essays on CRISPR technology
Importance of crispr
Importance of crispr
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Hey! It’s me, Christopher, streaming live from The Guardian! I know, I know; it’s already January 15, so I’m sure you’re wondering what today’s tantalizing topic is. Well, today I’m going to be informing you about Gene Editing-Rewriting the Code of Life. So let’s start with some basic background information. Each and every one of our bodies is made up of a chemical called DNA; simply it is the coding telling us to how to grow, live, and function. A gene is a small section of a DNA strand and these are what are inherited from your parents to determine your appearance. They are our body’s ‘biological templates’ to create proteins and enzymes to construct tissues and organs. Get this: humans have around 24,000 genes in them! Unfortunately, some …show more content…
people are born with genetic malfunctions, creating harmful diseases such as cystic fibrosis, sickle cell anemia, and muscle dystrophy. It’s not like they’re uncommon, too, because one in twenty-five children is born with a genetic disease. That’s what makes gene editing so exciting and essential. With gene editing, scientists and doctors would be able to rewrite the affected patient’s diseased DNA.
But wait! That’s definitely not all! Gene editing can do much, much more. It has already been used to actually modify patient’s immune cells to fight cancer or resist HIV infection. Researchers are also using gene editing to alter pig organs to make them safe to transplant into humans. Not only could gene editing be a huge step to treating various diseases, but it is also positively affecting the agriculture industry. It is a much quicker, cheaper alternative to conventional genetic modification-one that allows producers to perk up their crops without using genes from other organisms. Researchers have created seedless tomatoes, gluten-free wheat, and mushrooms that don’t turn brown with age. You’ve heard all the mind-boggling things it can do, so now I’m sure you’re wondering just how will it do these things? It is done using a molecular tool called Crispr-Cas9 and what it is does is it takes a guide molecule (otherwise known as the Crispr part) to find an exact area in an organism’s DNA and then cuts it with an enzyme (otherwise known as the Cas9 bit). The cell tries to fix the damage, which successfully turns the diseased gene
off. To repair a damaged gene, scientists can inject a healthy strand of DNA alongside the Crispr-Cas9 molecules.
Adams, J. U. (2015, June 19). Manipulating the human genome. CQ Researcher, 25, 529-552. Retrieved
but, is it a positive or negative for humankind? With this advanced genome editing technology we can form specially modified humans such as super soldiers and even hand pick what we want our children to look like before they’re even born. Gene editing can fix inherent diseases in a child by blocking the disease out of the embryo but, putting a child's appearance and health in the hands of a genome editor is extremely unethical, one single mistake can cause horrific defects and life-long struggles. Gene editors can fix what parents don't want their kids to have including attached earlobes, color of eyes, nostrils, and hair color. No creation on this planet is supposed to be flawless it would be unethical. If everyone was enhanced, there would be no meaning to the word. If all humans were born with desired traits, flawless features and perfect body types there would be some form of arrogance on what real life is. No one is or should be perfect it’s flaws that make each human individual and special. Gene editing is more evil than good. "So much has been done, exclaimed the soul of Frankenstein — more, far more, will I achieve; treading in the steps already marked, I will pioneer a new way, explore unknown powers, and unfold to the world the deepest mysteries of
Many people often ask, “Is it acceptable for human beings to manipulate human genes” (Moral and Ethical Issues in Gene Therapy). Most of the ethical issues centralize on the Christian understanding of a human being. They believe God made them the way they are and people should accept their fate.The Society, Religion and Technology Project have researched and found that countless people are curious if gene therapy is the right thing to do. They have a problem with exploiting the genes a person is born with due to the fact they consider it to be “playing God” (Moral and Ethical Issues in Gene Therapy). They are also concerned with the safety. On account of the unfamiliar and inexperienced technology. Gene therapy has only been around since 1990, so scientists are still trying to find the best possible way to help cure these diseases. Multiple scientists are cautious with whom they share their research. For the reason that if it were to get into in the wrong hands it could conceivably start a superhuman race. Author Paul Recer presumes using germline engineering to cure fatal diseases or even to generate designer babies that will be stronger, smarter, or more immune to infections (Gene Therapy Creates Super-Muscles). Scientists could enhance height, athleticism and even intelligence. The possibilities are endless. Germline engineering, however, would alter every cell in the body. People would no longer have to worry about the alarming and intimidating combinations of their parents’ genes. Genetic engineers are able to eliminate unnatural genes, change existing ones or even add a few extra. Like it or not, in a few short years scientists will have the power to control the evolution of
In September 14, 1990, an operation, which is called gene therapy, was performed successfully at the National Institutes of Health in the United States. The operation was only a temporary success because many problems have emerged since then. Gene therapy is a remedy that introduces genes to target cells and replaces defective genes in order to cure the diseases which cannot be cured by traditional medicines. Although gene therapy gives someone who is born with a genetic disease or who suffers cancer a permanent chance of being cured, it is high-risk and sometimes unethical because the failure rate is extremely high and issues like how “good” and “bad” uses of gene therapy can be distinguished still haven’t been answered satisfactorily.
Genetic engineering depends on the location and analysis of genes on chromosomes and ultimately DNA sequencing. The early cartography of the genes used the principles of Mendelian genetics . It is assumed that alleles that are transmitted together side by side are located on the same chromosome : it is said that are connected or linkage . These genes form a bridging group - linkage group : are the same for gametes and are usually transmitted together , so they do not have independent distribution. Crossing-over occurring during meiosis may cause these alleles can be exchanged between the chromosomes of a homologous pair .
Gene therapy focuses on the replacement of defective genes with modified functioning genes. Many diseases are caused by a defective gene meaning the body is incapable of producing essential proteins or enzymes. In its simplest form, gene therapy aims to identify the defective gene and fix this gene with the replacement of a normal gene (Senn).
"The aim is to decrease the fear of a brave new world and to encourage people to be more proactive about their health. It [Gene therapy] will help humans become better physically and even mentally and extend human life. It is the future” (Hulbert). Dr. Hulbert, a genetic engineer, couldn’t be anymore right; more time, money, and research needs to be put into gene therapy and genetic engineering, since it can cure certain illness and diseases that are incurable with modern medicine, has fewer side-effects than conventional drugs or surgery, and allows humans to be stronger physically and mentally at birth. Gene therapy or genetic engineering is the development and application of scientific methods, procedures, and technologies that permit direct manipulation of genetic material in order to alter the hereditary traits of a cell, organism, or population (NIH). It essentially means that we can change DNA to make an organism better. Genetic engineering is used with animals and plants every day; for example with genetic...
Over the past few decades, advances in technology have allowed scientists to actively manipulate the genetic sequence of an organism through a process called 'genetic engineering'. Many believe that this is a technique which we should exploit and take full advantage of as, after all, it may be the key to curing many hereditary diseases such as heart disease and cancer. It may very well be the solution to overcoming evolutionary barriers and allow us to breed new species. However, if you consider the unknown consequences we may have to face as a result of our futile experimenting, you would find that messing with a system as intricate as nature for curiosity's sake is hardly justifiable.
Genetically modified organisms can be plants or animals that have been genetically altered to produce or express a desired characteristic or trait. By genetically altering organisms such as crops, we can eliminate the use of pesticides by making the crops resistant to insects. We can also produce crops that are resistant to floods and droughts. Furthermore, with the use of molecular genetics, we are able to produce foods that are rich in nutrients and supplements. People in developing countries may not be fortunate enough to have a full course meal that contains nutrients from all four basic food groups. However, GMOs can with a little modification provide all the amino acids, vitamins, and minerals included in a good diet by simply consuming a genetically modified staple crop such as rice. In addition, by producing crops that are resistant to harsh environmental conditions as well as pests, we would see a rapid increase in the production of food thereby reducing and or!
Finally, some opponents of germline genome editing argue that it should not be allowed in clinical practice because it is unnatural. However, this argument is predicated on the incorrect assumption that “natural” is synonymous with “good”. These opponents should consider that birth defects and other genetic diseases and disorders are also natural. If society advocated for a totally natural existence, the medical system would not exist. Medicine exists primarily for people’s desire to defy nature and live as long and as healthily as we possibly can. This opportunity should also be afforded to future people, especially now that there are more technologically advanced ways of accomplishing it.
Want to avoid starting the zombie apocalypse? Well, here's why you should be opposed to the idea of gene editing. There are many things that can go wrong in the process of genetically modifying something. For example, genetically editing crops to become toxic to pests can help the food industry, but the pests could just simply adapt to the edited crops over time. Continuing to make the crops more harmful to the pests would leave our own health at risk. After all the genetic modifications made to the crops they wouldn’t even be consumable. By this time all the un-edited crops would have already been ridden of, causing us to lose a food source.
Genes are made of DNA – the code of life (Gene Therapy- The Great Debate!). The changes in genes may cause serious problems, which we called genetic disorder. In theory, the only method to cure genetic disorders is gene therapy, which basically means the replacement of genes in order to correct the loss or change in people’s DNA. Although gene therapy gives patients with genetic disorders a permanent cure, it is controversial because it has safety and efficacy problems, and raises ethical issues.
Before being used on humans, it was used on crops to enhance the livestock, to increase taste size and many other desirable traits in food, to make them more enticing to consumers, to make them easier to grow in certain weather conditions, and also to withstand pesticides needed to safeguard the crops. There is no proof of the long-term effects of genetic engineering. People have been worried about the effects of eating genetically engineered crops on their health, and because of the concern the Organic Trade Association doesn’t allow genetically altered products. It is an idea that has not been taken very seriously over the past decades and was only seen as a wildly imaginative miracle out of reach of scientists. Now that idea has become a very real process that seems like a dream come true to the many who see it as a miracle cure, but a nightmare to those who see it as spitting on the work of God and telling him he is now obsolete in the child bearing portion of the human life.
Scientists and the general population favor genetic engineering because of the effects it has for the future generation; the advanced technology has helped our society to freely perform any improvements. Genetic engineering is currently an effective yet dangerous way to make this statement tangible. Though it may sound easy and harmless to change one’s genetic code, the conflicts do not only involve the scientific possibilities but also the human morals and ethics. When the scientists first used mice to practice this experiment, they “improved learning and memory” but showed an “increased sensitivity to pain.” The experiment has proven that while the result are favorable, there is a low percentage of success rate. Therefore, scientists have concluded that the resources they currently own will not allow an approval from the society to continually code new genes. While coding a new set of genes for people may be a benefitting idea, some people oppose this idea.
Position Paper: Gene Therapy in Humans. Advancements in science and medicine are usually accompanied by a myriad of ethical and moral implications. The fairly recent advancement in genetics, called gene therapy, is no exception to the baggage of polarizing views that come with new technology. Gene therapy is an extremely hot topic in both the scientific world and everyday life. New technology, discoveries, and breakthroughs are rapidly occurring in the field every day.