LYMPHOMA
Introduction
Lymphoma refers to a blood cancer form that result from a faster than normal division of T or B lymphocytes; the condition also occurs when these cells live for a longer than the normal (Pace, Cassio & Glass, 2007). Organs in which the disease may develop include spleen, lymph nodes, bone marrow, alongside others. Ideally, this disease is a presentation of a lymphoid cells’ solid tumor. The disease’s treatment could entail chemotherapy, radiotherapy, and transplantation of bone marrow. Scientists state that the disease can be cured and that the cure depends on factors like its stage, histology, and type. Malignant cells have lymph nodes as their origin and resemble the node’s enlargement. There are also some extranodal sites of origin which include skin, bone, bowels, tonsils, and brain. There is close relationship between lymphomas and lymphoid leukemias whose sites of origin are also lymphocytes; however, the leukemias do not involve static tumors but bone marrows and circulating blood (Pace, Cassio & Glass, 2007).
Background
Lymphoma’s first description came in the year 1832, from Thomas Hodgkin, hence being named Hodgkin’s lymphoma. In the subsequent years, scientists made descriptions of other types of the disease thus various classifications of the same. A working formulation, of the year 1982 gained an immense deal of popularity as it came up with non-Hodgkin lymphoma category constituent of 16 diseases. Doctors are, however, abandoning the NHL label considering it to have limited usefulness because its 16 diseases have negligible similarity (Ansell, 2006). In the year 2008, the WHO came up with a later classification criteria constituent of 70 lymphoma types.
Biology of the Disease
Hodgkin lym...
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...observed in individuals of more than 60 years old. Lymphoma prevalence also varies with race; for example in the US, disease occurrence is higher among whites than Asian and African Americans (Gobbi et al, 2013).
Conclusion
Lymphoma is a form of cancer that affects the lymph systems with most cases of the disease occurring in developed countries. The disease is characteristic of various observable symptoms like enlargement of lymph nodes, weight loss, night sweats, and fever. Diagnosis of the disease makes use of tests like physical exams, X-rays, biopsy, and blood tests. Treatment makes use of targeted therapy, chemotherapy, biological therapy, radiation, and watchful development. Apart from the infection’s pathology, individuals may also experience other complications in life including suppression of the immune system, infertility, and transplant of stem cells.
Lymphoid tissue is made up of cells called lymphocytes, a type of white blood cell that fights infection. There are 2 major types of lymphocytes: B lymphocytes (B cells) and T lymphocytes (T cells). Normal T cells and B cells have different jobs. But because all the importance of these cells they can travel around the body spreading the cancerous cells. There are four stages for Hodgkin’s lymphoma when testing is completed the doctors can determine what stage the cancer is at and what treatment will be best suited to fighting the disease.
Lupus is more common in women than men, and although it can affect people of all ages, it is most commonly developed between 15 and 40. Lupus is also more common in African Americans, Hispanics and Asians.
I have chosen to write about the constellation Cancer (The Crab). I chose Cancer because it is one of only a handful of constellations that I am actually able to identify in the night sky. Cancer is one of the twelve Zodiac constellations; people whose birthdays fall between June 21st and July 22nd have Cancer as their sign. Cancer is the Latin word for crab, and despite the fact that the constellation looks more like a lobster then a crab, it is still referred to as a crab. The constellation is visible from the northern hemisphere from late winter to early spring.
Hodgkin’s lymphoma is a form of cancer in the lymphatic system. This type of lymphoma originates in the white blood cells, and spreads throughout the lymph nodes in the body. The cause of Hodgkin’s lymphoma is unknown, and it is sometimes found by chance. This disease is typically treated with chemotherapy and radiation and, if found in the early stages, the patient has a good chance of being fully cured.
The Emperor of All Maladies by Siddhartha Mukherjee is an in-depth analysis of the history of cancer. The book discusses the beginning stages of cancer when it was merely a confusing phenomenon for doctors that occurred for over a century. For example, "Childhood leukemia had fascinated, confused, and frustrated doctors for more than a century. The disease had been analyzed, classified, sub-classified, and divided meticulously” (Mukherjee 12). Mukherjee is a passionate physician and displays this in his work as a cancer researcher. Mukherjee book consists of his professional experiences working at the Dana-Farber
There are two types of lymphoma, Hodgkin disease and Non-Hodgkin lymphoma, and even though they are different they both begin the same way. Like other cancers, lymphoma results when cells divide too quickly or do not die because of a discrepancy in their genes. The cells that are affected in this type of cancer are white blood cells called lymphocytes. Lymphocytes make up around 20 to 40 percent of all white blood cells, and are divided into two categories, B or T. Both types help support the immune system by destroying infectious or foreign substances, but B lymphocytes make antibodies to fight these substances while T lymphocytes directly attack the unwanted substances. These cells work in the lymph system which is a part of the immune system. The main jobs of the lymph system are to protect the body from unwanted substances and to transport waste. The system includes many vital organs such as lymph nodes, spleen, bone marrow, thymus, and the digestive tract. When lymphocytes become cancerous they collect in the lymph nodes therefore blocking the passage of waste and other white blood cells while also using the nodes as a system to travel and spread to other parts of body. These cancerous cells do not die and become a burden for the body because they can no longer fulfill their ...
Elphee, E. E. (2008). Understanding the Concept of Uncertainty in Patients With Indolent Lymphoma. Oncology Nursing Forum, 35(3), 449-454.
The Phase I trial will be discussed here as it pertains to the topic at hand. The typical treatment for cervical cancer if surgery is not a viable option – like if the cancer has spread, then called locally advanced cervical cancer – is chemotherapy and radiation treatment at the same time. This phase I clinical trial is simply looking to add ipilimumab to this regimen, but once the chemo/radiation has been completed (LACC article). Chemo and radiation destroy tumor cells, which causes tumor-associated antigens to be released. Once released, these antigens are exogenous (outside the cell) and will be presented to helper T cells to initiate an immune response.
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...l risk factors that are fully linked developing multiple myeloma. Therefore, preventative measures remain unknown.
The lymphatic system is a link of tissues and organs that help clear the poisonous toxins, waste and further unwanted elements that are inside the human body. The key function of the lymphatic system is to transport lymph which is a watery fluid substance holding infection that are fighting white blood cells, all over the human body.
To classify ALL, physicians used to use what is called the French-American-British (FAB) classification to divided the disease into three categories called L1, L2, or L3, based on how the leukemia cells looked under a microscope(American Cancer Society, 2013)54. This method is now a thing...
Since 1979 the diagnoses of cancer have gone up nearly 20% in a generation as there is more people smoking, drinking, obesity and unfitness (theguardian website, 2011, para. 1). There has been in increase of women with the diagnosis, the diagnoses have risen up by 50% (459 per 100,00), men have risen from 20,000 to 24,000 (the guardian website, 2011, para. 2). Socioeconomic class does have an effect in some cases as cervical and lung cancers are more common in poor people while rates of breast cancer and melanoma are higher in the wealthy (ScienceDaily website, 2008, para. 1). Demographics could also have some effect as those of the wealthier group have more exposure to UV by traveling abroad for the holidays (ScienceDaily website, 2008, para. 5). In regards to smoking, deprived groups continue to smoke while the wealthier groups have quit smoking (ScienceDaily website, 2008, para. 7). Researchers have linked cancer to not only demographics, socioeconomic class but also race and
Bone cancer is classified into primary bone cancer & secondary bone cancer. Basically, Primary bone cancer starts in the bone; then the cancer initially forms in the cells of the bone; while the secondary cancer starts elsewhere in the body and gets spread to the bone.