Essay On Multiple Myeloma

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Multiple Myeloma
What is Multiple Myeloma?
Multiple myeloma, also known as myeloma, hematologic cancer, or cancer of the blood is a plasma cell cancer, a type of white blood cell made in the bone marrow that is responsible for creating antibodies. A Multiple myeloma diagnosis means a group of these plasma cells has become cancerous and is multiplying. This cancerous multiplication of plasma cells raises the the level of abnormal proteins in circulating blood, and reduces the space available in the bone marrow for making healthy plasma cells . Health problems caused by multiple myeloma can affect your bones, immune system, kidneys and red blood cell count. The lifetime risk of getting multiple myeloma is 1 in 149 (0.67%).

What different types of multiple myeloma exist?
IgG is the uncontrolled production of abnormal immunoglobulin (IgG) proteins, which fight bacteria and viruses. This abnormal immunoglobulin has no benefit in the body, and, as it increases in amount, it crowds out normally functioning immunoglobulins. This is the most common types of myeloma, accounting for 60-70% of all cases.

Light chain myeloma is the production of incomplete immunoglobins. Light chain myeloma causes only a portion of the immunoglobin protein (the light chain) to be produced, rendering these immunoglobins incapable of fighting infection. Light chain myeloma accounts for 20 percent of all multiple myeloma diagnosis.

Nonsecretory myeloma forms the level of M protein by producing myeloma cells too low to be detected by standard testing; it accounts for 1-2% of multiple myeloma diagnosis.

What are some symptoms of multiple myeloma?
There are no specific symptoms to detect multiple myeloma early. While symptoms may be present, they are often ve...

... middle of paper ...

...l risk factors that are fully linked developing multiple myeloma. Therefore, preventative measures remain unknown.

Famous people with multiple myeloma:
- Geraldine Ferraro – American attorney (Democratic Party politician)
• http://www.freebase.com/view/en/geraldine_ferraro
- Steve Boros – American Baseball Infielder, Coach, Manager
• http://www.freebase.com/view/en/steve_boros
- Phil Smith – American Professional Basketball player
• http://www.freebase.com/view/en/phil_smith
- Warren William – Broadway & Hollywood actor
• http://www.freebase.com/view/en/warren_william

Created by: Mikayla D. Williams

Peer Reviewed by:
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Websites:
- http://www.themmrf.org/
- http://www.cancer.org/cancer/multiplemyeloma/index
- http://myeloma.org/Main.action

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