1. Specific Aims A recent global analyses by the World Health Organization finds almost 20% of humanity (1.52 billion) will experience clinical-level depression during their lifetime, and one-half of those diagnosed with depression are also by diagnosed with an anxiety disorder (760 million)1. 2. Specific Aims Mood disorders express in memory, attention and physiological biases. Mood (affective) disorder are a group of diagnoses in the Diagnostic and Statistical Manual of Mental Disorders International Classification of Diseases system where a disturbance in the person's mood (emotional state) is hypothesized to be the main underlying feature of ailment2, 3. Studies show complex interactions between mood, attention, and memory. The ability …show more content…
to effectively modulate attentional resources implies the effective neural storage of items in visual short-term memory (VSTM); vital to attentional decision making and constructive human interaction. When ineffective or unwanted modulation of attentional resources exists, the ramifications are expressed in affect, behavior, and somatic disturbances. Our previous studies investigated the relationship high vs low mood-scores had upon an error-detection task, the Emotional Flanker (EF)4.
Significant reaction times differences were found between high versus low mood groups’ (see Figure 1; left). As well, significant within-group compatibility effects (responses to items congruent or the same as, versus items incongruent or opposite to, the central target item). This task incorporated a spatial element (near vs. far), whereas our subsequent research, the Emotional Flanker-Gratton (EFG)5, investigated the effects of sequential mood-stimuli on emotional attention in high vs. low mood-groups (see figure 1, right). The EFG revealed significant congruency sequence effects (difference between incongruent and congruent trials is typically strongly reduced when the previous trial was incongruent compared to when congruent) and supported EF low/high group findings. Sequence effects are calculated via the subject’s reaction times, which correspond to electrical brain impulses; measureable by various biomedical equipment. When the brain up-regulates the amount of control (i.e., electrical activity) in the Anterior Cingulate Cortex and Dorsal Lateral Prefrontal Cortex, more intense attentional control is exerted – resulting in a faster response, after a slower (compatibility effect) response to stimuli. Interestingly, high mood-score groups show consistent differences to control groups during attention tasks when viewing emotion-related
stimuli (even when set size, color, spatial frequency, object orientation where held constant).
Kaplan, H. I., Sadock, B. J., & Grebb, J. A. (1994). Synopsis of psychiatry: behavioral sciences,
I am quite fascinated by generalized control mechanisms and the role they play in the nervous system. I am also quite curious about the relationship between different generalized control mechanisms. The concept of mood and depression in particular have always interested me. I have always wondered what actually causes depression. Why can some people be in a perfectly good mood one day and then less than a week later start exhibiting the signs of clinical depression? I have always been curious about the role that experience and chemical imbalances play in depression and other mood disorders. I donUt totally understand how chemical depression can originate as the result of severe outside stressors in a personUs life. How can this stress go from simply stress in the experiences and environment of a person to a chemical imbalance? I have also wondered why certain people are more susceptible to depression than others. I am curious about whether genetics play a role in depression and whether certain people are more susceptible to depression because of the environment they live in or because of pharmacological reasons and genes. Throughout our class this year, I have wondered about the role that the I-function plays in depression. I find it interesting that it is possible to wake up one morning and be in a nasty mood even if I want to be in a good mood and my I-function is thinking RhappyS thoughts. Through my research for this paper I wanted to find out more about the different kinds of depression and exactly what goes on chemically in the brain when a person is depressed. I also wanted to do a little research on how depression can be treated. I wanted to try and determine how and when the line of simp...
...n fear and arousal (Schmahl, Berne, Krause, Kleindienst, Valerius, Vermetten &ump; Bohus, 2009). The work of dampening this arousal is carried out by the pre-frontal region of the brain. Brain imaging has revealed that personal differences in the capacity to activate areas of the prefrontal cerebral cortex, which is believed to activate inhibitory responses, predict the capacity to repress negative feelings (Williams Sidis, Gordon &ump; Meares, 2006). Acetylcholine and norepinephrine in addition to serotonin are the main neurotransmitters in the circuit involved in the regulation of emotions. Imbalance of these neurotransmitters in conjunction with increased GABA activity is believed to have the capacity to result in intense mood swings similar to those of borderline personality disorder (Schmahl, Berne, Krause, Kleindienst, Valerius, Vermetten &ump; Bohus, 2009).
Watson, D., & Tellegen, A. (1985). Toward a consensual structure of mood. Psychological Bulletin, 98(2), 219-235. doi: 10.1037/0033-2909.98.2.219
Weisman, M.M., Livingston, B.M., Leaf, P.J., Florio, L.P., Holzer, C. (1991). Psychiatric Disorders in America. Affective Disorders. Free Press.
Since chronic stress can turn into depression, it is essential to lay it out more clearly that 1 in 10 Americans experiences depression at one point or
Bearing in mind that an anxiety response is a result of various factors, there are different types of anxiety disorders. The most common type of anxiety disorders as described as specific phobias, social anxiety disorder (SAD), panic disorder (PD), generalized anxiety disorder (GAD), obsessive compulsive disorder (OCD) and post-traumatic stress disorder (PTSD). According to Anxiety and Depression Association of America (ADAA) (2016), specific phobias affect about 19 million adults in the U.S, while SAD affects 15 million, PD affects 6 million, GAD affects about 6.8 million, OCD affects about 2.2 million and PTSD affects 7.7 million adults respectively. Considering that anxiety disorders are the most common mental illness in the U.S, yet only about one-third of those suffering receive treatment (ADAA, 2016).
As many as 19 million Americans million are affected by mood disorders ( The two main types of mood disorders are bipolar disorder and major depressive disorder which are described as disturbances in mood, behavior and emotion.“ Bipolar disorder is a complex disorder in which the core feature is pathological disturbance in mood ranging from extreme elation, or mania, to severe depression usually accompanied by disturbances in thinking and behavior, which may include psychotic symptoms, such as delusions and hallucinations” (Craddock, Jones 1999). Major depressive disorder or unipolar depression is characterized by a consistent low mood and lack of interest in things typically enjoyed .A second classification of major depressive disorder, is dysthymic disorder which is a chronic but less severe form of major depression (John W. Santrock 2007). Also major depression has many subgroups including seasonal affect disorder and postpartum depression. While there are many treatment options for the symptoms of mood disorders and promising scientific research, much is still unknown about a disorder that affects so many lives.
Clinical depression is very common. Over nine million Americans are diagnosed with clinical depression at some point in their lives. Many more people suffer from clinical depression because they do not seek treatment. They may feel that depression is a personal weakness, or try to cope with their symptoms alone. On the other hand, some people are comfortable with admitting their symptoms and seeking help. Such a discrepancy may account for the differences in reported cases of depression between men and women, which indicate that more than twice the numbers of women than men are clinically depressed. According to the numbers of reported cases of depression, 25% of women and 10% of men will have one or more episodes of clinical depression during their lifetimes.
The topic of this essay will be to review the evidence that attentional bias causes anxiety. “There is widespread evidence of an attentional bias towards threat material in clinical anxiety” (MacLeod, Mathews & Tata, 1986; Mogg, Mathews & Eysenck, 1992). Certain treatments have been created for anxiety disorders that have been shown to reduce cognitive biases such as attentional bias, Fox et al (2005). This indicates that attentional bias is present within anxiety disorders. Stroop tasks have further developed research on attentional bias within anxiety as shown by Macleod (1991) and Macleod and Mathews (2002). Participants with anxiety disorders produce slower reaction times towards threat stimuli than the controls, indicating that attentional bias for threat related stimuli exists and has a greater effect on anxious individuals.
Journal of Attention Disorders. 17(2), 141-141. pp. 141-
Davison, G. D., Neale, J. M., & Kring, A. M. (2004) Abnormal Psychology (9th ed.). Hoboken, NJ: John Wiley & Sons, Inc.
There is a fine line between anxiety and depression. A line that is often times blurred. Although there are differences between the two, they also share many similarities, which can lead to false diagnoses for patients. It only gets more complicated when both illnesses are present. For example, The National Institute of Mental Health (2009) did a study of anxiety disorders and found that 53.7% of people reported they also experienced major depression as a secondary condition. These researchers also stated that people who are severely depressed do become anxious. In order to have a better understanding of anxiety and depression one must first clearly define the two conditions, understand the causes, look at the symptoms involved, and review the different treatment options available.
Many people feel apprehensive and miserable every now and then, but when does it take over their whole lives? Losing a loved one, doing poorly in school or work, being bullied and other hardships might lead a person to feel sad, lonely, scared, nervous and/or anxious. Some people experience this on an everyday basis, sometimes even or no reason at all. Those people might have an anxiety disorder, depression, or both. It is highly likely for someone with an anxiety disorder to also be suffering from depression, or the other way around. 50% of those diagnosed with depression are also diagnosed with an anxiety disorder.
Depression is one of the most common psychological problems. Each year over 17 million Americans experience a period of clinical depression. Thus, depression affects nearly everyone through personal experiences or through depression in a family member or friend.