Curare, also known scientifically as, Chondrodendron tomentosum is a substance which is bitter and grows on the stems and barks of some South American plants. Curare is known to paralyze the motor nerves. Traditionally, curare was used by South American Indians to poison their arrows by combining the curare obtained from plants and various poisons from animals and then mix everything up to make syrup like substance. The Indians then would coat the syrup on to their arrows and use the arrows to kill prey and later eat them. When the South American Indians eat the dead prey, they do not get poisoned because in order to get poisoned by curare, you need it to be in your blood stream. Once the curare is in your bloodstream it acts as a neuromuscular blocking agent, basically it disrupts the signals between nerve cell and muscle cells. First, curare begins to affect the muscles of the toes, ears, and eyes. After curare moves on to the muscles of the neck and limbs and finally it affects the muscles that help the lungs function, this induces …show more content…
The discovery of Curare dates back to seventeen-thirty five. French explorer Charles Marie de la Condamine, who spent couple of years in South America exploring, took samples of curare back to France. In the nineteenth century, doctors had tried to use curare as a muscle relaxant for the treatment of rabies, tetanus, and epilepsy but failed due to a number of reasons. In the eighteen-seventies, in England, curare was used to keep animals still during procedures but was later banished because of public outcry. The first successful use of curare was developed by Harold King in nineteen-thirty five, when he isolated the active principal of curare, tubocurarine. Daniele Bovet, a Swiss-Italian pharmacologist created an artificial curare because in nineteen-forty seven the side effects of curare were unknown. Bovet made the artificial curare known as
Attention-getter: Every day in America millions of people are being poisoned, and you could very well be among them.
A remarkable breakthrough in medicine occurred in the late 1800s through the work of Louis Pasteur. Pasteur's experiments showed that bacteria reproduce like other living things and travel from place to place. Using the results of his findings, he developed pasteurization, which is the process of heating liquids to kill bacteria and prevent fermentation. He also produced an anthrax vaccine as well as a way to weaken the rabies virus. After studying Pasteur's work, Joseph Lister developed antisepsis, which is the process of killing disease-causing germs.
SUMMARIZE: The article focuses on studies related to anesthesia which were conducted on dogs by researchers. Topics discussed include Arthur Guedel anesthetizing a dog using tracheal tube and cocaine crystals numbing cornea. It also goes on to talk about the numbing of Nazi dogs by Jews using cocaine. Also the use of curare by a surgeon named Mario Jascalevich which resulted in a neuronal cell death. Numerous stories on chemicals tested on animals, preferably dogs and facts were presented. (78
Animal testing has gone back as far as three hundred B.C.E with the Greek physician and philosopher, Aristotle (*). Then there was Galen, a Greek physician, who studied animals in Rome and learned more about medicine, made advancements in understanding anatomy, physiology, pathology, and pharmacology. To modern society, Galen is referred to as being the father of vivisection. In the twelfth century in Spain, Ibn Zuhr, an Arab physician who made use of animal experimentation that led to testing the effectiveness of surgical procedures, first on animals, and then applying the information to human patients. Though most of his testings were on goats, much of his research went into postmortem autopsies and dissections. (Hajar) (Naik)
Incapacitating agents, in some form, have been experimented with since as early as 600BC when Greek King Solon ordered his troops to throw Hellebore roots into streams that provided water for his enemies. King Solon’s goal was to incapacitate the enemy with diarrhea. Then in 200BC an officer in Hannibal’s army, Maharbal, poisoned wine with Mandragora and left if for the uprising tribes in Africa he was facing. The tribe greedily drank the wine and the Maharbal either killed or captured the disabled enemy soldiers. In one incident in 1672 the Bishop of Muenster used grenades filled with Belladonna; however ...
There is no doubt that the particular layout of space of the 1893 World’s Columbian Exposition reflected the gender inequalities that existed within American society at the time. In particular, the Women’s Building offered a microcosm of the prejudices that dominated the overall landscape of the 1893 World’s Columbian Exposition. Although the men who organized the Columbian Exposition were unable to exclude women’s achievements altogether from the exposition, they were successful in relegating them into a bounded unit that overwhelmingly categorized their contributions as different and marginal, framing womanliness as “soft,” “delicate,” and “refined.” Discussions of the Women’s Building’s architectural aesthetics highlights such gendered dimensions of the Columbian Exposition quite clearly.
In the past, poisoning was one of the most popular forms of murder. There are countless natural substances in the world that when ingested into the body in high doses, can become lethal to the human body. What made this form of murder so famous is that most poisons mimic common medical diseases, leading physicians to believe a victim died of natural causes (Ramsland, n.d.). Aside from murder, this forensic discipline is also essential for determining accidental deaths and suicides. As stated earlier, forensic toxicology is the examination of toxic substances in human tissues, organs, and body fluids that may have contributed or caused death to an individual (Tilstone, Savage, Clark,
In the year 3000, the planet Earth is a desolate wasteland. It has been a little over a half a century since the “big one” hit the Earth. The majority of the human race has been eliminated with only a few hundred remaining. The only ones who have survived barely made it on to the spaceship as the big one smashed the Earth. Marcus is one of the many survivors coping with solar winds and debris floating around the Moon. After half a century, the survivors are running out of supplies on the moon. The crew must go back to post-apocalyptic Earth and explore the wasteland. Marcus knows that this journey will not be an easy one. They encounter different
This particular English 102 class pertains to going in depth of the heroic. This means to me that we will discuss what characteristics it takes to be a hero and how those characteristics have evolved in classic stories that many of us all know in today’s society. This course will help me develop better research skills, different and more efficient writing styles, and how to communicate with others. The objective is to be able to research a specific topic from a certain academic aspect that inspires myself, which in my case is nursing. For example, nurses have a duty like heroes and they are much alike, to help save people from something that is endangering that specific person whether it be a disease or a villain. The goals for English 102
The Inupiat people inhabit the Northern Slope Borough. This is the Northwestern most part of Alaska. It contains the Northern most American city Barrow, known as Utqiaġvik in Inupiaq, the Inupiat’s native language. There are four main types of Inupiat, the Bering Strait Inupiat, the Kotzebue Sound Inupiat, the Northern Alaska Coast Inupiat also known as Tareumiat and the Interior North Inupiat also known as Nunamiut however each clan has its own traditions and customs and within each town there can be 1 or more clans. (cite) There are roughly 13,500 Inupiat in Alaska. The Inupiat are a part of a group called Inuit which includes tribes in Greenland and Canada. They prefer the term Inuit or Inupiat to Eskimo so for the sake of this paper the term Inuit will be used when discussing the people as a whole. All Inuit speak a form of the language
Today in America, personal ambition serves the common good. Motivates successful individuals drive social and economic progress and set strong examples for others. In order to help the common good, the common good must first help themselves. Instead of relying on others and the government for assistance, we should all reflect on ourselves and see what we can do for ourselves. If everyone helped themselves no one would need to be helped. Reliance on others is a huge problem with in our society, including a reliance on the government, other citizens and technology, and a reliance on others to help us achieve everyday activities. If we all tried self helping ourselves the world would be a much better place.
Insite is the first legalized drug injection site in North American, it is located in Vancouver, Canada. Insite offers a safe place to inject or smoke illegal drugs, primarily heroin. Insite does not provide the drugs but they do offer medical help to anyone needing it. In 2009, 276,178 visits were recoded, and 484 overdoses occurred with no deaths, (Wikipedia, n. d).
Many scientists believe that it might be true that rhino horn can cure poison because they are made up of keratin, and poison is strongly alkaline and many alkaline react chemically with keratin. Rhino horn is also used as a symbol of someone’s success and wealth. Rhinos use their horns foe parental care, to protect their calves from predators, also use them for foraging behaviour, mate choice and for defending their territory. Dehorning helps them from not killing each other with their horns while fighting for their
Physostigmine is a white crystalline alkaloid extracted from the beans of Physostigma Venenosum plant. The poisonous effects of Physostigma Venenosum have been known since nineteenth century. William Freeman Daniel was the first scientist who observed the first use of calabar beans. He traveled to Africa with a exploring discovering mission. Somehow, he ended up at the Old Calabar near the Niger river. He observed the people, the culture, they way of life that they were lived in, and government. He documented everything that he saw at the Old Calabar. Interestingly, he noticed that justice system was harsh. The documented that court was composed of the king and several chiefs and Calabar beans were used as a justice system.
My Honors research is a composite of work done both here at Howard University and at the National Institutes of Health in Bethesda, Maryland. Here on campus, I am in the laboratory of Dr. Mark Burke, an assistant professor in the Department of Physiology and Biophysics of Howard University’s College of Medicine. I began in the lab at the beginning of this year, where my primary responsibility was to learn and develop the relevant skills and techniques to succeed within his laboratory. These included: primate brain tissue processing (sectioning and slide mounting/dehydration), immunohistochemistry, tissue staining and keeping an updated lab notebook. In the spring of this year, I was accepted into the Amgen Scholars Program, which gave me the opportunity to conduct my own research project at the National Institutes of Health over the summer. I was in the lab of Dr. Hans Ackerman in the Sickle Cell Branch of the National Heart, Lung, and Blood Institute, and the nature of my project focused on the expression of a tight junction protein known as