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Biological influences of cocaine
Biological influences of cocaine
Phsyiological effects of cocaine research paper
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Cocaine Cocaine is a powerfully addictive drug of abuse. Individuals who have tried cocaine have described the experience as a powerful high that gave them a feeling of supremacy. However, once someone starts taking cocaine, one cannot predict or control the extent to which he or she will continue to use the drug. The major ways of taking cocaine are sniffing or snorting, injecting, and smoking (including free-base and crack cocaine). Health risks exist regardless of whether cocaine is inhaled (snorted), injected, or smoked. However, it appears that compulsive cocaine use may develop even more rapidly if the substance is smoked rather than snorted. Smoking allows extremely high doses of cocaine to reach the brain very quickly and results in an intense and immediate high. The injecting drug user is also at risk for acquiring or transmitting HIV infection/AIDS if needles or other injection equipment are shared. Health Hazards • Physical effects. Physical effects of cocaine use include constricted peripheral blood vessels, dilated pupils, and increased body temperature, heart rate, and blood pressure. Some cocaine users report feelings of restlessness, irritability, and anxiety, both while using and between periods of use. An appreciable tolerance to the high may be developed, and many addicts report that they seek but fail to achieve as much pleasure as they did from their first exposure. • Paranoia and aggression. High doses of cocaine and/or prolonged use can trigger paranoia. Smoking crack cocaine can produce particularly aggressive paranoid behavior in users. When addicted individuals stop using cocaine, they may become depressed. This depression causes users to continue to use the drug to alleviate their depression. • Long-term effects. Prolonged cocaine snorting can result in ulceration of the mucous membrane of the nose and can damage the nasal septum enough to cause it to collapse.
Cocaine is a classified ‘Schedule II’ drug, also known as “crack”, and “coke” it is a powerful drug, and addictive stimulant well known as a psychoactive substance. That comes from a plant called coca leaf that has been around since the mid-1800s and throughout the 20th century. “In the mid-1980s, addiction to the drug was seen as exaggerated or dismissed as psychological and not addiction” (Miller, Gold, Smith, 1997, p.62). In the past, cocaine’s original use was for medical purposes as local anesthetic for surgeries. Now its usage is illegal and this drug is immersed into the body through various ways. However,...
Porrino, L.J., Smith, H.R. Nader, M.A., Beveridge, T.J.R. (2007). The effects of cocaine: A shifting target over the course of addiction. Prog Nueropsychopharmocol Biol Psychiatry, 31(8), 1593-1600. (Porrine et al., 2007).
David, A.G (2013). Cocaine use disorder in adults: Epidemiology, pharmacology, clinical manifestations, medical consequences, and diagnosis. ©2014 UpToDate, Inc.
Cocaine (C17H21NO4) comes from the leaf of an Erythroxylon coca bush. It is a drug that effects the central nervous system. It causes feelings of euphoria, pleasure, increased energy and alertness. People under the influence of cocaine often do not feel the need for food or sleep. They also feel energetic and may talk a lot. However, depending on factors such as environment, dosage, and the manner in which the drug is taken, cocaine can have adverse effects such as violent, erratic behavior, dizziness, paranoia, insomnia, convulsions, and heart failure to name a few. Long- term effects of cocaine include, but are not limited to strokes, heart attacks, seizures, loss of memory, and decrease in learning capability (1).
All drugs have a negative effect on the nervous system, but few can match the dramatic impact of cocaine. Cocaine is one of the most potent, addictive, and unpredictable recreational drugs, and thus can cause the most profound and irreversible damage to the nervous system. The high risk associated with cocaine remains the same regardless of whether the drug is snorted, smoked, or injected into the user¡¯s bloodstream. In addition to the intense damage cocaine can cause to the liver, intestines, heart, and lungs, even casual use of the drug will impair the brain and cause serious damage to the central nervous system. Although cocaine use affects many components of the body, including vision and appetite, the most significant damage cause by cocaine takes place in the brain and central nervous system.
A study done by Puig and colleagues (2012) compared the effects of intermittent (once daily) and binge (three times a day) cocaine treatment for 1 and 14 days after the last cocaine injection on spontaneous locomotor activity and dopamine levels in the NAc in rats. The intermittent treatment led to a spontaneous increase in dopamine and in locomotor activity at the exact hour which rats were habituated to receive a cocaine injection (Puig, Noble & Benturquia, 2012). The binge treatment led to sensitization of locomotor effects of cocaine, associated to a dopamine release sensitization in the NAc (Puig, Noble & Benturquia, 2012). These results show the addictive nature of cocaine and the behavioural and sensitization effects it has on the animal, which can be related to the effects it can possibly have on humans (Puig, Noble & Benturquia,
Many people avoid the use of crack because of the harmful chemicals used in creating the drug. One of the reasons why crack became popular is because of not needing to inject the drug hence less risks of being infected by the AIDS virus. Carroll (2000) states cocaine is the most powerful stimulant of natural origin. Most users snort or inject the drug to enable a quicker “high.” Cocaine use brings on many health problems.
According to Gawin (1991), cocaine addicts report that during binges everything including: nourishment, sleep, money, family, responsibilities, and survival, are all focused on cocaine. After long-term cocaine use, cocaine addicts can develop digestive disorders, weight loss, physical deterioration, deterioration of the nervous system, increase heart rate and blood pressure which can lead to heart attack and stroke (The Columbia Encyclopedia, 2013). Cocaine produces its effect of euphoria when an accumulation of dopamine is form in the synapse (NIDA,
Cocaine is made from leaves of the coca plant. It's highly addictive and dangerous to the user's health. In 2014, approximately 1.5 million people ages 12 or older were current users of the drug. https://www.drugabuse.gov/publications/research-reports/cocaine/what-scope-cocaine-use-in-united-states
The use of cocaine can result in heart and brain damage. It can cause strokes and constricting arteries in the heart, causing heart attacks (Dictionary.com). Cocaine use is associated with an increased risk of a range of somatic, psychological, and social problems, such as cardiac toxicity, psychosis, mood and anxiety disorders, aggression and crime” (Burda, DesLauriers & Goldstein,2009). Cocaine is also the most frequent drug related cause of emergency room visits in the United States (Burda et al., 2009). Cocaine causes some symptoms in the central nervous system like euphoria and increased self confidence when taken at a lower dose. When it is taken at a higher does it causes hallucinations, aggressiveness and disorientation. Continued use of cocaine caused the depletion of stored dopamine and this causes intense cravings for cocaine. With all the reported cocaine overdoses in the news and the fact that as children we are told about the effects of drugs, people still use them every day. Knowing just doesn’t seem like enough of a deterrent. We even see drug addicts on street corners and still it’s not enough. The drug addictions and drug overdoses will continue until a person has everything taken from them, and then maybe they will learn that the high is just not worth
Cocaine use makes the fight center in the limbic center hyper-activated, as well as the emotional triggers are over stimulated, which makes sense as to why Jordan slaps his wife and then tries to kidnap his own child after snorting cocaine. All of this rage and emotion were running through him and it made him explode. They also state that cocaine raises the heart rate and constricts blood vessels, Jordan’s physical state showed signs of heart rate acceleration and then he would do another line of cocaine. Throughout the movie, cocaine was used which meant that Jordan was a compulsive cocaine user. Inaba, Cohen and Pharm (2014) state that besides hereditary and environmental vulnerability, like Jordan’s case of stress with the FBI investigating him, people use cocaine compulsively to recapture that first rush they had, cocaine changes the way the brain works and, therefore, makes it more vulnerable to cravings, and to control the symptoms of depression. I think this movie shows every stage of cocaine use. From when he had stress, so he had to find a way to cope, to feeling the symptoms, to leading to other drugs, to getting in trouble with the law, to finally trying to sober up. What is great about this movie is that it shows something that can happen to someone and as well was based on something that actually happened
The powder cocaine is heated and a solid material isolates the boiling assortment. Next, it is removed and dried out and cut into “rocks” ( Streetdrugs). Crack cocaine gets its name from the crackling sound it makes when it’s simmered. Since coca trees grow primarily in South America, it is very easy to produce crack and many statistics show that US and Canada has the most crack addicts. Crack cocaine is also considered a stimulant because it increases the action of the central nervous system and speeds up the metabolism resulting in increased energy and alertness. Since it’s a stimulant and a narcotic, once a person takes it he yearns for it more. Taking crack cocaine produces a sense of euphoria, well-being (University Of Maryland). Symptoms of crack cocaine are both physical and psychological. Physical and psychological withdrawal begins if the addict lacks crack cocaine. Once he hits on the drug, his tolerance level boosts; he takes increased amounts of the drug each time to get desired effects. Psychological indications include the following: excessive thoughts over buying crack cocaine, regular craving ...
Therefore, there is no reuptake and the dopamine increases, creating this intense euphoria (NIDA, 2013). Cocaine carries a high risk of addiction, since tolerance continually increases. Heart attack, stroke, and malnourishment are other side effects (Ackerman, 2014). The emotional effects include paranoia, anxiety, and irritability (Ackerman, 2014). Cocaine is a potent substance, and the effects on a pregnancy can be devastating.
Cocaine is a powerful addictive drug that affects the whole body in different ways. This drug has been around in America since 1855. In this year there were products that the average person used that had amounts of cocaine in it. The products that had cocaine in it were the beverage coke cola and medicine for numbing your gums. But before manufactures’ were using cocaine in things we use, three thousand years before the ancient Inca people use to chew coca leaves, which is one of the ingredients of making cocaine. They chewed coco leaves to get there heart racing and to speed up their breathing so they can work longer hours and because they lived where there was thin air. Also by them chewing the coco leaves it would tell their body that they aren’t hunger because they didn’t have enough food to eat. Cocaine was really popular between 1970s and 1980s in New York City. It was a large amount of people that died from this drug around this time.
Many people that have smoked marijuana also try other drugs to get another type of high. Cocaine is a powerful stimulant that effects the brain directly. This powerful drug takes effect in very small doses by making a person feel more alert or energetic. Though people may think the drug helps them perform tasks faster with fewer complications, it also carries a list of effects. Some include constricted blood vessels, dilated pupils, high temperature, high heart rate, and bizarre behavior. Some...