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Evaluation essay of the overuse of antibiotics
Antibiotic resistance case study answers
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Although some pharmaceutical companies maintain active antibiotic research programs, many have halted their antibiotic programs. So despite encouraging research and development of new anitbacterial drugs is necessary, new drugs alone are not the answer. Ciprofloxacin (Cipro) was introduced in 1987, and it works by “allowing topoisomerases to cut DNA, but not “glue” the ends back together. The result is that the bacterium can no longer replicate its DNA, keeping the bacterial population in check” (Guilfoile 2007). However, Ciprofloxacin resistance is over 30 percent in some species of bacteria. Furthermore it was concluded, “Overuse of Cipro could lead to the development of bacterial resistance to the drug, which would make it useless for treating infections”(Guilfoile 2007).
In the late 1980s, about 5% of S. aureus strains were resistant. Accordingly, to avoid this rapid rise in resistance in the future, new drugs should be reserved for use in special circumstances, particularly for infections that are resistant to current antibiotics. The FDA or the CDC may need to provide regulations on the use of new antibiotics. Otherwise, if new drugs are overused or misused, resistance to the new antibiotics could also develop quickly. Consequently, it is for this reason and others mentioned above why Methicillin-Resistant Staphylococcus Aureus (MRSA) is resistant to antibiotics.
In conclusion, Methicillin-Resistant Staphylococcus aureus is an important and dangerous human pathogen. Hundreds of thousands of people acquire S. aureus infections in the United States each year, and it normally does not affect healthy individuals unless there is a break in the skin from injury or surgery where the bacteria can find a home. These ...
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...earch in this area. Plus, we also need to become better consumers for our own personal antibiotic use because bacterial infections can also derive from misuse and overuse of an antibiotic drug. We must prevent the spread of bacteria by washing our hands, fruits, and vegetables. Even raw eggs and undercooked meat are suspects in creating bacterial infections. Furthermore, to be properly vaccinated is a major fight against such infections. So “although humans are not yet close to winning the war against S. aureus, these measures may help provide the weapons we need to have a fighting chance” (Freeman-Cook and Freeman-Cook 2006). Perhaps, one day in the near future the fight against bacterial infections will be resolved and there will no longer be a need for posing the hypothesis of “Why Methicillin-Resistant Staphylococcus Aureus (MRSA) is antibiotic-resistant.”
Methicillin-resistant Staphylococcus aureus is similar to regular hospital acquired MRSA in that it is resistant to cefazolin, and antibiotics similar to cefazolin. However, it differs from MRSA in that it doesn't display MRSA’s common risk factors, and is susceptible to other various antibiotics.
Spironolactone is a light cream colored stable powder that has a faint odor (6). Spironolactone was created by G.D. Searle and is currently the only product that directly treats hyperaldosteronism, the excess production of aldosterone in the body (9). Spironolactone is in the aldosterone-receptor blockers medication category. Spironolactone is a diuretic mostly used to treat hypertension and edemas (8). The discovery that led to the development of spironolactone was aldosterone being found to be the third hormone in the adrenal cortex (6). Aldosterone is created in the zona glomerulosa that is a region of the adrenal cortex. The information know aldosterone led to research into the creation of compounds and medications
In the last decade, the number of prescriptions for antibiotics has increases. Even though, antibiotics are helpful, an excess amount of antibiotics can be dangerous. Quite often antibiotics are wrongly prescribed to cure viruses when they are meant to target bacteria. Antibiotics are a type of medicine that is prone to kill microorganisms, or bacteria. By examining the PBS documentary Hunting the Nightmare Bacteria and the article “U.S. government taps GlaxoSmithKline for New Antibiotics” by Ben Hirschler as well as a few other articles can help depict the problem that is of doctors prescribing antibiotics wrongly or excessively, which can led to becoming harmful to the body.
A successful business relies strongly on strategic planning and development. Businesses strategies define a company’s future through vision and mission statements, marketing, operations, and financial performance. The purpose of this paper is to analyze and evaluate the business strategy of a public traded company, Salix Pharmaceuticals, Inc. Throughout this paper, the writer will provide a company overview, a SWOT analysis, and explore the strategic objectives and contingency plans of Salix Pharmaceuticals, Inc.
Resistance arises from mutations that are not under the control of humans, but the evolution of bacteria has been sped along by the overexposure of antibiotics to both people and animals. The number of antibiotic-resistant strains of bacteria in an area is closely related to the frequency that antibiotics that are prescribed (Todar, 2012). Patients often unnecessarily demand antibiotics to treat common colds or simple illnesses that are not caused by bacteria. Instead, these infections are caused by viruses which, unlike bacteria, are unaffected by antibiotics. Incorrect diagnosis can also lead patients to using unnecessary antibiotics, which can sometimes be even more dangerous than otherwise left untreated. Besides the fact that antibiotics kill off beneficial bacteria in the intestines, misuse of antibiotics provides an opportunity ...
Germaphobes beware: the next incurable global epidemic is already here and, to make matters worse, you may unknowingly come in daily contact with it. Methicillin-resistant Staphylococcus aureus, commonly known as MRSA, is the villain of Maryn McKenna’s book, a terrifying tale of the negative consequences of modern medicine. It’s the kind of book that keeps you awake at night, itching to read the next chapter- and worried you could become infected. Through vivid case studies and scary scientific evidence about what appears to be an unbeatable pathogen, McKenna’s book, Superbug, is one that will make you afraid to step foot in a hospital ever again.
According to USA Today, U.S. doctors are prescribing enough antibiotics to give to 4 out of 5 Americans every year, an alarming pace that suggests they are being excruciatingly overused. In fact, Dr. Aunna Pourang from MD states, “to give you an idea of how high the pressure is to prescribe antibiotics, I didn’t get a job once because during the interview I told the lead physician that I only prescribe antibiotic prescriptions when they are warranted.” The development and widespread obsession of antibiotics, or drugs that kill bacteria and thereby reduce infection, has helped billions of people live longer, healthier lives. Unfortunately, the more we rely on and abuse antibiotics, the more bacteria develop resistance to them, which makes treating infections that much more challenging and leads to the growth of drug-resistant strains of bacteria. Research from the Center of Disease Control found that two million people in the United States become infected with antibiotic resistant bacteria, while 23,000 people die from such infections each year. Americans often aren’t informed on the power of the human body and rush to assumptions when perfection isn’t present. In a nutshell, the obsession of antibiotics is quite deadly and needs to be addressed before it’s too
Over the years humans have tried every possibility to overcome the health problems, spread of epidemics and infections, disease control and have worked towards a healthy society free of disease and health problems. They have succeeded to a great extent. The book “Good germs, bad germs” describes that though the life expectancy is now far more as it was in previous eras. Epidemic problems and infectious diseases are now getting lesser and lesser and humans are being treated successfully. The hygienic conditions have also been improved so as to ensure least growth of microbes, germs, parasites and bacteria. Antibiotics have been invented to address diseases and infections caused by bacteria and viruses. With all these substantial efforts the biologists, physicians and scientists have triggered another epidemic which is even more severe. They have killed those microbes and bacterial species which were human friendly and as a result of either their disruption or mutation, pathogenic bacteria have even become more active and resistant to treatments. This has led to increased ineffectiveness of antibiotic drugs, low immunity and various infections and inflammatory diseases. The chlorinated water for drinking and food processing along with excessive hygienic conditions indicates our fight against these bacteria and germs. Further, these antibiotics are even given to the livestock which becomes our food and as result many of their resistant germs end up in our digestive tract and other organs. Thus, the war against microbes through excessive cleanliness and use of antibiotics has resulted in antibiotic resistance among humans, which has become one of the prominent problems of medical science
Even though S. aureus is mainly associated with food poisoning, the bacterium can penetrate the skin or other mucous membranes to invade a range of tissues which will cause a variety of infections. Superficial infection of the skin can cause boils, impetigo, styes (infection of the glands or hair follicles of the eyelids), folliculitis, and furnacles. All of these infections are charac...
Staphylococcus aureus is a bacteria that is abundant in many places. It can even be found in some of our bodies. These bacteria are harmless as long as none of them are Methicillin resistant Staphylococcus aureus (MRSA). Methicillin is the name of a family of antibiotics that includes penicillin. This MRSA is the deadly superbug that has developed resistant to antibiotics. Statistics show that MRSA contributes to more US deaths than does HIV. It has become a huge threat to every country as the outbreaks can be a surprising one. This threat is caused by the evolution of the bacteria. These superbugs have evolved a resistance of antibiotics which makes them extremely difficult to treat. One article states, “In the early 1940s, when penicillin was first used to treat bacterial infections, penicillin-resistant strains of S. aureus were unknown — but by the 1950s, they were common in hospitals. Methicillin was introduced in 1961 to treat these resistant strains, and within one year, doctors had encountered methicillin-resistant S. aureus. Today, we have strains of MRSA that simultaneously resist a laundry list of different antibiotics, including vancomycin — often considered our last line of antibacterial defense.” [1]
This turn of events presents us with an alarming problem. Strains of bacteria that are resistant to all prescribed antibiotics are beginning to appear. As a result, diseases such as tuberculosis and penicillin-resistant gonorrhea are reemerging on a worldwide scale (1). Resistance first appears in a population of bacteria through conditions that favor its selection. When an antibiotic attacks a group of bacteria, cells that are highly susceptible to the medicine will die.
The most effective way to combat pathogenic bacteria which invade the body is the use of antibiotics. Overexposure to antibiotics can easily lead to resistant strains of bacteria. Resistance is dangerous because bacteria can easily spread from person to person. Simple methods for preventing excessive bacterial spread are often overlooked. Not all preventative measures are even adequate. Doctors and patients often use antibiotics unnecessarily or incorrectly, leading to greater resistance. Antibiotics are used heavily in livestock and this excessive antibiotic use can create resistant bacteria and transfer them to humans. In order to reduce resistant bacteria,
Infection control is very important in the health care profession. Health care professionals, who do not practice proper infection control, allow themselves to become susceptible to a number of infections. Among the most dreaded of these infections are: hepatitis B (HBV), hepatitis C (HCV), and human immunodeficiency virus (HIV). Another infection which has more recently increased in prevalence is methicillin-resistant Staphylococcus aureus (MRSA). These infections are all treated differently. Each infection has its own symptoms, classifications, and incubation periods. These infections are transmitted in very similar fashions, but they do not all target the same population.
There are many medical professionals who believe that the rise of antibiotic resistance is a result of the overuse and misuse of antibiotics. Dr. Jim Wilde, a paediatric emergency medicine physician at the Medical College of Georgia believes that the medical profession is losing the war against resistance...