Black Elderberries Research Paper

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Black elderberries (Sambucus nigra L.), a deciduous shrub is often used as a traditional medicine, and it is used for common cold and influenza. The bioactive chemical of Sambucus nigra is the anthocyanins. Anthocyanins, plant colorants that responsible for colors such as red, purple, or blue, and in addition, it also provides various health benefits. Studies have shown that anthocyanins for animal and in vitro have decreased necrotic and apoptotic cell death and lower the infarct risks through anti-inflammatory and relaxant effects on coronary arteries. Krawitz and colleagues conducted a study to find out if a standardized elderberry liquid extract will work against bacterial infections and influenza types A and B. They investigated the ability of the extract of elderberries to weaken or decrease the growth of of human pathogenic influenza A and B virus strains. Krawitz and colleagues worked with A/Thailand/KAN-1/2004 (KAN-1, H5N1) and B/Massachusetts/71 (B/Mass) in cell culture. …show more content…

The ratio of the extract is 18:1, and the anthocyanin concentration is 3.2%. The concentration of anthocyanin is done by using a mechanical filtration procedure, where semipermeable members separate substances based on molecular sizes. Bacterial strains, S. Pyogenes, group C and G Streptococci, and B. catarrhalis, were obtained from patient samples and cultivated in sheep blood agar plates at 37 degree Celsius. The antimicrobial activity was determined by the growth of the bacteria in the plated agar gels with elderberry liquid extract concentrations of 5%, 10%, 15% and 20%. Viral strains of KAN-1, H5N1 and B/Mass were used for the experiment. MTT assay and focus size reduction assay were the methods for testing the inhibitory activity of elderberry liquid extract of the viruses in cell

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