Arsenic Accumulation
By Hemanth Ande Research Plan
A. Specific Aims
Arsenic is a common element that has been part of the human civilization for more than 2000 years. It has been used as medicine in the western and eastern world in ways that would not be sanctioned today. In modern times Arsenic is used in agricultural, medical use and industrial use. Although it is considered a toxic compound in high dose, humans are exposed to the compound every day. Currently there is no comprehensive report detailing levels in our accumulation of Arsenic in human body thru the food industry and their effects on health of individuals. This proposal is to research the arsenic levels found in our food source from poultry and grains to the human body. This
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Arsenic can be found in most drinking waters and foods. The amount that is accumulated is limited due to the body excreting it from the body. The arsenic that is not excreted may cause harm to bodily functions if it above a threshold. Arsenic is very reactive and may form more toxic analogs. Arsenic toxicity shows up rapidly and must be treated with chelation therapy quickly or face permanent damage. It is unable to be detected without equipment in food, because it does not change a foods texture or change the taste of food. It is element of choice for food industry but it can be quite …show more content…
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Attention-getter: Every day in America millions of people are being poisoned, and you could very well be among them.
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The proposed research will identify gene expression traits of breast cancer cells chronically exposed to arsenic during different periods of exposure. These results will allow us to develop gene profiles and identify arsenic-associated genes. By identifying arsenic-associated genes, we can determine if these genes are involved in molecular functions and biological processes. This study can assist future studies of mammary tumors with elevated arsenic levels and will provide insight into breast cancer progression due to the accumulation of arsenic. Our proposed research will demonstrate the impact of arsenic on the estrogen receptor and on breast cancer carcinogenesis. We hope this study will highlight the importance of studying the effects of prolonged arsenic exposure on breast cancer.
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Arsenic is the 20th most common element in the earth’s crust and can be found naturally in our environment. There is around 0.006 to 0.03 ppm or arsenic distributed in seawater, and 20 ppm of arsenic in soil (before pesticides). Every human will ingest about 0.5 to 1 mg of arsenic in a day from food and water, because arsenic is present in higher quantities in se...
elemental phosphorus is highly poisonous and only used for homeopathic treatment the only phosphates which are non-toxic are natural named above phosphates which are in food and the following
Genetic modification is very harmful for human beings; it has a huge negative effect on animals’ and humans’ health. The manipulation of the genes of crops and animals may cause health damage. “Animal toxicity studies have shown that genetically modified foods may toxically affect several organs and systems” (Arvanitoyannis, 162, 2011). These studies concluded that genetically modified foods are dangerous and they may become one of the most harmful issues in the world. According to Arvanitoyannis research genetically modified foods cause some common toxic effects such as: hepatic, pancreatic, renal or reproductive effects and may alter the hematological, biochemical and immuno...
Ungar, Peter S. Evolution of the Human Diet: The Known, the Unknown, and the Unknowable. Oxford: Oxford UP, 2007. Print.
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