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ANTHRAX
Anthrax is a zoonotic bacterial infection that can be transmitted either through contact with affected animals or as a biological weapon (Jones 4). Its use in biological warfare has, however, been controlled and such cases are very few. The few cases have stirred the attention of most people, which has consequently increased public awareness in the disease. It normally affects ruminant animals such as cattle, horses, goats and sheep and then transmitted to humans. Humans cannot transmit the infectious bacteria to other humans.
Causes
The main cause of anthrax was identified by Dr. Robert Koch, as the Bacillus Anthracis bacteria (Paolo 104). The German physician who was curious about the mysterious death of animals in his community.
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The area of infections swells but the ugly sore can disappear without treatment. The Bacillus Anthracis spores can also be ingested by animals after which, the spores turn into its rod-like form, and their carcasses are then ingested by other animals or humans (Jones 5). The ingestion of the anthrax causing Bacillus Anthracis can lead to a fatal infection. However, infection through inhalation is the most potent form that one can contract anthrax. Once the spores are inhaled, they move to the chest where they enter the lymph glands. They then multiply and spread as well as release toxins that often lead to fatalities. Cases of human anthrax infections in most developed countries are quite rare. The few cases reported worldwide are isolated to underdeveloped countries that do not have public health resources and regulations, which not only prevent humans from infection, but also animals, as well as its spread through animal products. Most infections through ingestion involve the slaughter of infected animals and distribution of their meat products. There have also been increased reports of skin infections mainly with individuals who work with leather and more specifically drum makers who use raw leather. However, most people in developed nations only have to worry about anthrax infections when the Bacillus Anthracis bacteria are used in biological warfare. In 2001, the US postal system was used to mail anthrax spores to …show more content…
The fact that it is a zoonotic infectious disease means that its prevention has to include both human elements, as well as animal elements. The prevention of animal infections is the first line of defense against anthrax. There are currently veterinary vaccinations for animals, which ensures that they develop immunity against the Bacillus Anthracis bacteria spores. Healthy animals do not spread zoonotic diseases to human. The second line of defense involves controlling the contact between people and any infected animals, as well as their products. There is currently a vaccine that can be used on individuals who work in anthrax prone environments such as vets, people engaged in the military duty, laboratory technicians who work with infectious diseases and workers in factories that process goat hair imported from different parts of the world. The efficacy of human vaccines is, however, low which means that they have to be administered regularly. The fact that the vaccine has possible side effects in some people has also limited its use to high risk individuals. The CDC, as well as the department of defense, have different strategies that prevent the use of anthrax as a biological weapon (Lutwick and Lutwick 12). Currently, vaccines are injected into the fat or muscle that is under the skin, but there are positive indications of an oral vaccine in the
A remarkable breakthrough in medicine occurred in the late 1800s through the work of Louis Pasteur. Pasteur's experiments showed that bacteria reproduce like other living things and travel from place to place. Using the results of his findings, he developed pasteurization, which is the process of heating liquids to kill bacteria and prevent fermentation. He also produced an anthrax vaccine as well as a way to weaken the rabies virus. After studying Pasteur's work, Joseph Lister developed antisepsis, which is the process of killing disease-causing germs. In 1865 before an operation, he cleansed a leg wound first with carbolic acid, and performed the surgery with sterilized (by heat) instruments. The wound healed, and the patient survived. Prior to surgery, the patient would've needed an amputation. However, by incorporating these antiseptic procedures in all of his surgeries, he decreased postoperative deaths. The use of antiseptics eventually helped reduce bacterial infection not only in surgery but also in childbirth and in the treatment of battle wounds. Another man that made discoveries that reinforced those of Pasteur's was Robert Koch. Robert Koch isolated the germ that causes tuberculosis, identified the germ responsible for Asiatic cholera, and developed sanitary measures to prevent disease. (1)
The 2001 anthrax attacks was one of the worst bio-weapon attacks on the US in history. The attacks where done through the mail. The anthrax was placed in envelopes with a letter and mailed from various locations to different people and organizations. The anthrax filled letters ended up killing 5 people, causing 17 to become sick and exposing anthrax it is believed to as many as 30,000 people. During the mail process spores of anthrax from the letters escaped and got on mailroom equipment exposing postal employees. If a person was exposed to enough anthrax and developed symptoms they typically died in a few days. Postal workers during the attacks where told that anthrax will appear as a white powder t...
Botulism is a rare but very serious paralytic illness that is caused by the botulinum toxin that is produced by the bacterium Clostridium botulinum. C. botulinum is a gram positive, anaerobic, spore forming bacterium that is naturally occurring in soil. Botulism dates back to the eighteenth century when the first food borne botulism was documented. During this time many people were doing home fermented sausages and this was thought to be the cause of botulism. This is how the toxin got its name since “Botulism” in Latin comes from “botulus” which means sausage. E. van Ermengen was the first to discover the microbe in 1897 after there was a food borne outbreak in Ellezelles, Belgium. To date there are six forms of botulism but only two forms were known until the twentieth century which were food borne and wound botulism. The first type of botulism is food borne which is a result of ingesting food that contains the pre-form toxin. Some foods that this typically occurs in are home canned vegetables, cured pork and ham and smoked or raw fish. Wound botulism is the result of C. botulinum spores growing in a contaminated wound with in vivo production. Most people that get wound botulism usually have deep and contained avascular areas and many people also had compound fractures. Wound botulism is on the rise in the U.S. because of the use of illicit drugs, “the majority were linked to injectable drug use, particularly with so-called ‘black tar heroin’ and others with nasal or sinus lesions due to chronic cocaine sniffing.” (CDC website) Another form of botulism is infant botulism. This is caused from the endogenous production of toxin germinating spores of C. botulinum in the intestines of the infants. Also feeding an infant...
Linkous, J. (2004). More details on new anthrax search. Retrieved Oct. 06, 2005, from CBS News Web site: http://www.cbsnews.com/stories/2004/10/05/national/main647441.shtml.
On September 18th and the weeks following, a multitude of letters containing the Bacillus Anthracis bacterium were mailed to various New York news stations. Individuals at 5 different stations became ill with similar symptoms that included vomiting and shortness of breath. This began the nationwide panic known as the Amerithrax Investigation. The Amerithrax investigation was said to be the worst biological attacks in all of US History. Three weeks later, on October 9th, two more letters, containing the anthrax bacterium was mailed to two Democratic senators. In all of the 7 attacks, over 22 people developed infections, over half being life-threatening. The letters themselves confused federal investigators. In the sets of letters addressed to the media, certain T’s and A’s were bolded. When added together, the groups of letters formed 3 codons that corresponded to 3 amino acids. These amino acids pointed federal investigators towards a possible culprit, Bruce Edwards Ivins, a scientist for the US government in Frederick, Maryland.
Necrotizing Fasciitis (flesh eating bacteria ) from an essay by Katrina Tram Duong, edited by S.N. Carson M.D.
Hochadel, M. (2014). Mosby's Drug Reference for Health Care Professionals (fourth edition ed.). : Elsevier.
Bacillus anthracis or anthrax is bacteria that infect thousands of people a year worldwide. Mostly found in the hinds and hair of grazing animals like cattle and sheep, the bacteria can stay dormant for years until contacted. Contact can occur through broken skin, eating infected meat, or inhaling infected dust from hides through the mouth or nostrils. Normal contact through the skin begins forming malignant skin ulcers that are dark black in appearance. If left untreated, the blisters lead to blood poisoning and eventually death. Eating contaminated meat not fully cooked can cause intestinal infection also leading to death. Surprisingly, many people survive contact of the skin and very few cases of intestinal infection exist. However, inhalation of infected dust or spores are much more deadly because the symptoms resemble a common cold...
Louis Pasteur, in 1881, discovered the anthrax vaccine. Anthrax is an infection caused by many bacteria cells called “Bacillus”. These bacteria make “spores” which have a protective shell. This disease is most common in farm animals. They live in soil, and affect domestic a...
...merithrax Investigation :. : Journal of Biosecurity, Biosafety and Biodefense Law., 31 July 2012. Web. 23 Apr. 2014. .
Humans are not the only ones who can be infected with Anthrax; livestock can also be infected with the bacteria. Animals such as cattle, sheep, or goats infected with anthrax will display the following symptoms; weakness, staggering fever, and difficulty breathing. These animals will also experience blood stained or tarry discharge from the nose or anus that continues to ooze even after the animal dies.
Wear gloves and proper cloths if handling the infected animals to prevent the direct contact.
There are thing that make people more susceptible to contracting zoonotic diseases. Either it’s knowingly or unknowingly, humans are prone to the dangers of being direct targets of zoonotic diseases. Zoonotic diseases are transmittable in various ways weather through ingestion or direct contact. There are countless numbers of zoonotic diseases some more commonly known than others but all equally important. Preventing the contraction or spread of zoonotic diseases is easily manageable with medication and vaccines along with following small tips that not only protect humans but the animal population as well.
Treatment of zoonotic infections in both animals and humans is not only a humanitarian action, but also shortens the length of sickness and, hence, the period of communicability, thereby providing a valuable measure in countering and controlling of the spread of zoonotic diseases (Mantovani, 1992; Webber, 2005). However, the diminishing utility of current antibiotics in the face of rising bacterial resistance and the stagnant development of new antibiotics constitute the main obstacles for achieving an effective treatment which further underscores the urgent need for the development of alternative therapeutic options (Mohamed et al., 2014). This scourge is further compounded by intracellular zoonotic pathogens, such as Mycobacterium, Salmonella, Listeria, and Brucella that reside and thrive inside mammalian cells (Seleem et al., 2009a, 2009b; Nepal et al., 2015). Treatment of infections caused by these intracellular pathogens is very challenging because most antibiotics are unable to access intracellular replicative niches and achieve the optimum therapeutic concentrations within the infected cells (Seleem et al., 2009a, 2009b). For instance, the mortality rate in human listeriosis remains high (20-30%) even
It all started because Great Britain was afraid that Germany and Japan had a great advantage in biological technology in comparison to them. They were testing to see the range of spread of the anthrax spores. Great Britain tested its weapons on the coast of the Island of Gruinard in Scotland were they thought it was far enough from they coast so it would not contaminate or hurt the mainland. In the year of 1943 throughout many experiments that were conducted it was proven that sheep and cattle were affected with anthrax. The British government thought of decontaminating the island that that meant that they had to brushfire they entire island to kill all of th...