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Anemias case study
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Anemia is a disease that is commonly seen in veterinary medicine. This disease can be described as having low amounts of red blood cells and a reduced amount of hemoglobin in the circulating blood, which reduces the oxygen-carrying capacity of the blood. It develops from loss, destruction or lack of production of red blood cells. Anemia is usually a secondary disease caused by another disease or medical condition. There are three different types of anemia; regenerative, non-regenerative and relative.
In regenerative anemia, the bone marrow is responding to the anemia by increasing the erythrocyte or red blood cell production. This means that there will be an increase in immature red blood cells in the circulating blood. On a blood smear it is likely to notice nucleated red blood cells (nRBCs), polychromatophils, an increase in reticulocytes, and also Howell-Jolly bodies (HJ bodies). The cause of this type of anemia is usually hemorrhage or hemolysis. Since the bone marrow is responding, it is likely that the red cell mass will eventually return to normal once the bone marrow has produced enough red blood cells to make up for the significant loss. Since the patient has lost a substantial amount of blood, albumin and globulin levels are usually decreased. The mean corpuscular volume (MCV) of the animal is going to be increased during this time because of the fact that the reticulocytes are larger than mature erythrocytes. The mean corpuscular hemoglobin concentration (MCHC) will be decreased. This is decreased as a result of the immature red blood cells, especially the reticulocytes, since they are larger cells that have less hemoglobin, because the bone marrow is trying to produce cells as quickly as possible, but due to that t...
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... the patient gets to ten percent dehydrated he or she will have sunken eyes, dry mucous membranes, a prolonged capillary refill time and a delayed skin tent. Anything past ten percent dehydration is usually fatal, the animal will become unresponsive and go into shock and eventually die.
Works Cited
ASPCA. (2014). Dehydration. Retrieved May 5, 2014. From http://www.aspca.org/pet-care/dog-care/dehydration.
Hendrix, C. M., & Sirois, M. (2007). Laboratory procedures for veterinary technicians. St. Louis, Mo: Mosby Elsevier.
Summers, A. (2007). Common diseases of companion animals. St. Louis, Mo: Mosby.
Veterinary Medical Clinic. Anemia, canine and feline. Retrieved May 5, 2014. From http://www.vetmedclinic.com/?p=288.
Voigt, G. L., & Swist, S. L. (2011). Hematology techniques and concepts for veterinary technicians. Chichester, West Sussex, UK: Wiley-Blackwell.
In this experiment, we determined the isotonic and hemolytic molar concentrations of non-penetrating moles for sheep red blood cells and measured the absorbance levels from each concentration. The results concluded that as the concentration increased the absorbance reading increased as well. A higher absorbance signifies higher amounts of intact RBCs. The isotonic molar concentration for NaCl and glucose is 0.3 M. The hemolysis molar concentration for NaCl and glucose is 0.05 M. Adding red blood cells to an isotonic solution, there will be no isotonic pressure and no net movement. The isotonic solution leaves the red blood cells intact. RBC contain hemoglobin which absorbs light, hemoglobin falls to the bottom of the tube and no light is absorbed. Determining the isotonic concentration of NaCl and glucose by finding the lowest molar concentration. In contrast to isotonic molar concentration, hemolysis can be determined by finding the
Although blood transfusions in the veterinary market are infrequent and the market scope is limited, Oxyglobin has the potential to become a lucrative investment for Biopure. Based on the approximate 355,000 blood transfusions (please see Exhibit 1 for the calculations behind this estimate) performed on animals in 1995, a definite opportunity exists for Oxyglobin within the veterinary blood market. Since the number of blood transfusions conducted in 1995 represented on average only 2.5% of animals suffering from acute blood loss, increased availability of animal blood could possibly stimulate the market.
results in the need for more blood. Since more blood is needed to fill the
In modern times, the experimentation on animals has led to just as many advances in medical science as there are in veterinary science and practice. Ibn Zuhr paved the way for basic surgical procedures that advanced over time as the anatomy of humans and animals were not seen as being one and the same. Blood transfusions came about through ...
My interest in and understanding of the field of veterinary science has only been heightened with the time I have spent on various valuable work experience placements over recent years, especially during the four weeks in small and mixed animal practices in England, Wales, and Ireland. Spending time in these four very different practices allowed me to observe a wide range of routine and emergency
Norkus, Christopher L. Veterinary Technician’s Manual for Small Animal Emergency and Critical Care. Chichester, West Sussex. UK: Ames. Iowa: Wiley-Blackwell, 2012.
The interest in studying Rhesus disease stems from an aspiration to understand blood and its’ components at a cellular level. In order to recognize what factors lead to this disease and what components of the cell can be used as indicators/markers to diagnose it, one must have a general idea of the concepts involved in cellular processes. This paper will focus on the causes of hemolytic disease, including natural and/or surgical & medicinal occurrences that cause isoimmunization; how antigens and antibodies are involved, and the effectiveness of Rh immunoglobulin will also be considered.
Aplastic Anemia is a form of cancer that affects the bone marrow. Bone marrow is a soft tissue that is located on the inside of larger bones. This disease I rare and is not restricted for any gender. Aplastic Anemia occurs when the bone marrow stops producing enough red blood cells, white blood cells and platelets for the body. Platelets are another form of cell that do not contain a nucleues. They circulate in the blood and keep us from bleeding. When the marrow produces these cells, the cells are normal in the way they function, but the marrow does not produce enough of the cells in order for the body to function properly. The word Aplastic actually means “a failure in development”.This disease was first discouvered in 1888 by Dr. Paul Ehrilch. He discouvered this disease after he studied a case where a preganant women died of bone marrow failure. In 1904 this condition was classified as Aplastic Anemia. The causes of this disease are un known. Risk factors of this condition tthat can increase your chnace of Aplastic anemai include exposure to envoirnmental toxins, paint , oil and coal emmsiosns, industrial soilvents, certain viruses or medications, medications used to treat rheumatoid arthiritis,bone marrow diseases and preganancy. This disease can be inhearited or caused by envoirnmental substances. When Aplastic anemia is heriditary it is less comon. Heriditary Anemia is caused by the genes being passed down from parent to child. People who have heriditary anemia have other development or genetic abberants. Faconi is the name used when aplastic Anemia is herediatary. Children with abnormal chromosomes are likely to inherit this condition. One who has herediatary Aplastic Anemia will have abnormalities in...
Blood transfusions allow for infected blood cells to be cycled out and replaced by fresh new blood cells in hope that hemoglobin levels will be restored within the body. When treating a person with liver disease it’s almost routine for them to experience several blood transfusions a month in order to help restore properly working blood cells back into their bodies. Blood transfusions are also a more structurally sound medical procedure when compared to several medications or radiation therapy alternatives, which can in turn cause a number of other problems. Another example of a disease that can be supported by the cycling of blood is Anemia. There several different types of anemia including aplastic, fanconi, hemolytic, and sickle cell anemia. The Mayo Clinic describes Anemia as “condition in which you don't have enough healthy red blood cells to carry adequate oxygen to the body's tissues”. Hematologists have been prescribing their anemia patients with several blood transfusions a month in hopes of training their bodies to make proper working blood cells once again. A study posted in the Journal of Palliative Medicine was conducted on 64 volunteer patients with several different forms of anemia to see if blood transfusions would benefit their hemoglobin values over a 15-day period. It turns out that 95 percent of the patients had some
When dogs don’t drink enough, it causes them to be dehydrated. “Dehydration is a lack of water in the body” (Dehydration and Water Needs in Dogs). Most of the body of dogs is water. Some dogs get way too hot outside and can get dehydrated. Dehydration can cause many effects to dogs. Dogs will drink more to stay hydrated if it is hotter. Water is used for most dogs systems. You have to keep clean water out at all times. If dogs get too dehydrated, their organs could shut down and they could die (The Importance of Water for Dog Nutrition). Some dogs can get dehydrated easier then other if they have problems or illnesses. Some symptoms of dehydration are dry mouth or depression. If your dogs are dehydrated, they
Red blood cells are carriers of oxygen. A percentage of these cells contain hemoglobin, which has the capacity to combine with iron. It's the iron-hemoglobin molecular structure that helps carry oxygen-rich blood from the lungs to your tissues and in return, delivers carbon dioxide back to the lungs to be expelled. A CBC with Differential that shows low red blood cell levels can indicate anemia. RBCs comprise about 40% of total blood volume; the RBC count is the number of red blood cells per cubic millimeter of blood (Rauen, 2012). Normal red blood cells values vary a...
...tment. It is important to treat the underlying cause of the disease first before attempting to treat the animal for iron-deficiency anemia (Grace, 2011). Retrovirus diseases are more common in Cats that have suffered anemia due to their weakened immune system. Contraction of other infections and diseases whilst undergoing treatment may also affect prognosis. (Brown, 2012)
Thalassemia is a blood disorder transferred through families. It occurs when the body makes less hemoglobin than needed or an unusual form of hemoglobin. Hemoglobin is the protein in red blood cells that carry oxygen. The disorder makes an excessive amount of destruction of red blood cells. This eventually leads to anemia.
What is anemia it is a medical condition in which the red blood cell count or hemoglobin is less than normal. Anemia can appear on anyone short, tall, skinny and or fat anyone can get it is not some condition that can be spread by physical contact. Having anemia is caused by the levels of blood cells ether decreasing or increasing.
"Humane Care and Use of Laboratory Animals." AALAS Foundation. 2005. American Association for Laboratory Animal Science. 2012 .