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What is leukemia
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What is Leukemia? Leukemia is a cancer in blood forming cells that are in early stages of development. Most of the time the white blood cells, but some types of leukemia start in other types of blood cells. Blood cells are form in bone marrow. Any of these cells can turn into a leukemia cell, once this happens the cell does not mature like it should. The cell may start to produce rapidly and the mutated cells probably won’t go through apoptosis like they should. These cells build up in the bone marrow and crowd out the healthy cells. Typically, leukemia cells get into the blood stream rather quickly. From the blood stream they can spread to places like lymph nodes, spleen, liver, central nervous system or other organs where the leukemia cells can cause those other cells to function irregularly. To understand where and how leukemia occurs it helps to know a little about the blood and lymph systems. Bone marrow is soft inner part of the bone where blood cells are formed There are three different types of major blood cells; white blood cells, red blood cells, and platelets. In infants active blood cells are found in almost in all bones but by the teenage years they are found in mostly flat bones (skull, shoulder blades, ribs, and pelvis) and the vertebrate. Bone marrow consist of a small number of blood stem cells, more mature blood forming cells, fat cells, and supporting tissues to help the tissue grow. They go through a series of changes to make new blood cells. With this process 1 of 3 things is made- red blood cells, white blood cells, or platelets. Red blood cells carry oxygen from the lungs to all the other parts of the body and transport carbon dioxide back to the lungs. Platelets are cell fragments made by a type of bone... ... middle of paper ... ...ous cells into the spinal cord or brain. Facts about leukemia: 1. Leukemia is the most common cancer in both children and teens. It accounts for almost 1 in 3 childhood cancers. But overall childhood leukemia is a rare disease. 2. ALL is more common in white children compared to African-American and Asian-American children. It is also more common in boys than it is in girls. AML occurs almost equally in boys and girls of all races. 3. The 5-year survival rate for children with ALL is more than 85%, children with AML have a 5-year survival rate of 60% to 70%. Reported rates for children with JMML are 50%. 5-year survival rates in children with CML aren’t very helpful because some live for a long time without the leukemia being cured, but the reported rates are 60% to 80%. Rates may be higher now with new medicines but they haven’t been used long enough to be sure.
Treatment depends on number of factors like the health of a person and their age, treatments can be very strenuous on the body but almost no surgery is required. Chemotherapy and radiotherapy o combined making treatment for lymphoma very effective and giving it a high survival rate.
AML is the most common form of acute leukemia among adults and accounts for the largest number of annual deaths from leukemias in the United States with an estimated 18,860 new cases and 10,460 deaths anticipated in 2014 (Cancer Facts & Figures 2014). In the Indian scenario, even though there are not many published data in AML incidence and prevalence, it is noted that the median age diagnosis of AML is much lower when compared to the western population. The median age in Indian population is between 41-45 years (Phillip et al, Unpublished data, CMC, Vellore, Dunna, Rajappa et al. 2010, Abraham, Varatharajan et al. 2012)
Over one million Americans in the United States are living with or have been diagnosed with leukemia. That’s a big amount of people. I chose to do my research paper on leukemia because two years ago I lost my grandma to the cancer. I wanted to know more about the disease and what was happening to her. I researched the different types, risk factors, symptoms, treatment, and what kind of research is being done to help cure leukemia. Leukemia is a cancer of the blood cells that start in the bone marrow. During leukemia the bone marrow starts to make a lot of abnormal white blood cells or “leukemia cells”.
Leukemia is a cancer of the blood cells, which start in the bone marrow. The disease develops when the blood cells produced in the bone marrow grow out of control. The cause for leukemia is unknown.
While lymphoma is a complex cancer of the lymph system that can have devastating effects, it can be overcome. Over 75% of those with intermediate-risk lymphoma have at least a five year survival rate. And that rate is likely to increase as detection and treatment options improve with new genetic research and lymphoma vaccine developments. Maybe one day there will even be a cure.
Steen, Grant R. and Joseph Mirro. Childhood Cancer: A Handbook From St.Jude Children's Research Hospital . Cambridge, MA: Perseus Publisher, 2000.
Cancer develops when cells in the body grow out of control. Any cells in your body can become cancer and spread to other areas of the body. Childhood non-Hodgkin lymphoma (NHL) is a particular type of cancer that forms in the lymph system. The lymph system is part of the body’s immune system. The immune system plays an important role in protecting the body from foreign substances, infection, and diseases. The lymphatic system consists of a fluid (lymph), vessels that transport the lymph, and organs that contain lymphoid tissue. The cancerous cell in
“Each year in the United States alone, nearly 32,000 adults and more than 2,000 children develop leukemia, a cancer of the blood cells”. Acute and chronic leukemia are the two kinds of the disease. Acute leukemia developments much more rapidly, chronic leukemia advances gradually, and the immune system is damaged slower. (Panno 36). Leukemia is one of many systemic diseases. Each disease affects the body differently. Leukemia affects the immune system, which affects the body by "feeling extremely sick, complaining of recurrent infections, bleeding, bruising, bone tenderness, fever, chills, sweats, weakness, fatigue, headaches, or swelling in the neck, or armpits”. Otherwise, an individual might have not any indications entirely and the disease might be discovered accidental from a checkup blood examination. When finding acute leukemia typically comes to instant hospitalization. Since leukemia victims require numerous transfusions of blood, patients have to be treated at medical establishments. Acute leukemia is treated by chemotherapy, which contains two stages: an initiation stage, where an individual is forcefully treated with a mixture of strong medications to kill the leukemic cells entirely, and a consolidation stage, using the similar or dissimilar medications, and starts as soon as the illness has gone into remission (Mayfield 1). The normal action for leukemia contains radiation and chemotherapy, which destroys the ca...
Nothing seems more rewarding than being able to hear that all the hard work paid off. After months or years of fighting an uphill battle with cancer, there is finally a moment of peace when the word "remission" is spoken. Unfortunately, this word does not mean the cancer has been permanently cured, and some people never get to hear that word which is longed for from every cancer patient. In general, cancer is one of the leading causes of death in both children and adults. Unlike many other diseases, cancer is an extremely versatile illness; it can be found in many different forms with an uncountable number of causes. This creates a difficulty in finding a permanent cure. When it comes to the frequency in specific types of cancer, it greatly depends on the age and sex of a person. According to Med Net, while Leukemia is most common in adolescent years, the majority of adult males with cancer suffer from cancer of the prostate gland, and when it comes to women, the most frequent is breast cancer.
...l risk factors that are fully linked developing multiple myeloma. Therefore, preventative measures remain unknown.
Acute lymphocytic leukemia (ALL) is a form of cancer that occurs when the lymphoid stem cell is affected thereby causing abnormal white blood cells to build up in the bone marrow. This cancer rapidly produces and replaces healthy cells with immature lymphoblast. The leukemia cells moves into the bloodstream to other organs and tissues where further growth and division occurs. The proliferation of cancer cells to other area produces a variety of symptoms. ALL typically occurs in children under the age of 15, however it can happen at any age. ALL is
How does one see the symptoms for childhood cancer? First one must know that there are many different types. There are forty different types of children’s cancer, including: Leukemia, Lymphoma, Sarcomas, cancers of the nervous system, liver cancers, kidney cancer, and more. Out of these cancers, the two most common childhood cancers are Leukemia, and brain tumors. What is leukemia? It is a cancer in which the bone marrow and other organs that produce blood produce and increased amount of immature or abnormal white blood cells. The symptoms of leukemia are paleness, excessive bruising, pain in the joints, and fatigue. Brain tumors are formed when a massive amount of cells are produced on the brain. The symptoms for this are frequent headaches, vomiting, seizures, decreased coordination, weakness, and problems concerning vision.
The Phase I trial will be discussed here as it pertains to the topic at hand. The typical treatment for cervical cancer if surgery is not a viable option – like if the cancer has spread, then called locally advanced cervical cancer – is chemotherapy and radiation treatment at the same time. This phase I clinical trial is simply looking to add ipilimumab to this regimen, but once the chemo/radiation has been completed (LACC article). Chemo and radiation destroy tumor cells, which causes tumor-associated antigens to be released. Once released, these antigens are exogenous (outside the cell) and will be presented to helper T cells to initiate an immune response.
In case you're wondering what leukemia is, let me tell you. Leukemia is cancer of the body's blood-forming tissues, which is also involved with the bone marrow. Leukemia is
Leukemia is a form of blood cancer that makes more white blood cells than red blood cells in the bone marrow. The white cells don’t work the way we use the red blood cells. Our body uses red blood cells to function properly not white blood cells. All the white blood cells do is fight infections. The extra white blood cells do not work right and that causes problems in your body and that’s when leukemia starts.