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Acute lymphoblastic leukaemia essay
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Compare and contrast acute lymphocytic leukemia and acute myelogenous leukemia in children. What are possible presenting features and diagnostic criteria? What are the cure rates with treatment?
Acute lymphocytic leukemia (ALL) is a form of cancer that occurs when the lymphoid stem cell is affected thereby causing abnormal white blood cells to build up in the bone marrow. This cancer rapidly produces and replaces healthy cells with immature lymphoblast. The leukemia cells moves into the bloodstream to other organs and tissues where further growth and division occurs. The proliferation of cancer cells to other area produces a variety of symptoms. ALL typically occurs in children under the age of 15, however it can happen at any age. ALL is
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According to the World Health Organization diagnostic criteria, ALL is diagnosed when “lymphoblasts account for more than 20% to 25% of cells”(Epocrates, 2014). Symptoms of ALL can depend on which areas of the body the cancerous cells had spread to. However generalized symptoms include fever, weight loss, fatigue, night sweats and loss of appetite. Recurring infections, bruising easily and bleeding are common indicator of shortages of normal blood cells associated with ALL. Patients could also have swelling in the abdomen if the abnormal cells build up in the liver and spleen. Joint pain could occur if the leukemia cells increase inside the joint or near the bone. If the cells build up to the brain or spinal cord, it could cause weakness, seizures, vomiting, facial numbness or blurred vision (American Cancer Society, …show more content…
(2014). Signs and Symptoms of acute lymphocytic leukemia. Retrieved from http://www.cancer.org/cancer/leukemia-acutelymphocyticallinadults/detailedguide/leukemia-acute-lymphocytic-signs-symptoms
Cancer Treatment Centers of America. (2014). Leukemia Types. Retrieved from http://www.cancercenter.com/leukemia/types/tab/acute-lymphocytic-leukemia/
National Cancer Institute. (2014). Childhood Acute Myeloid Leukemia / Other Myeloid Treatment. Retrieved from http://www.cancer.gov/cancertopics/pdq/treatment/childAML/Patient/page1
Epocrates. (2014). Diagnostic Criteria, World Health Organization Classsification of Tumours of Haematopoietic and Lymphoid Tissues. Retrieved from https://online.epocrates.com/u/2936273/Acute+lymphocytic+leukemia/Diagnosis/Criteria
Epocrates. (2014). Acute myelogenous leukemia. Retrieved from https://online.epocrates.com/u/2936274/Acute+myelogenous+leukemia/Diagnosis/Criteria
National Cancer Institute. (2014). Childhood Acute Lymphoblatic Leukemia Treatment. Retrieved from
Pediatric oncology has been so very rewarding in many ways, but also so very cruel in a few ways. The good days are great, but the sad days are heartbreaking. But beyond the death and the suffering, there is a whole other layer of
Chronic Myeloid leukemia (CML) is a blood and bone marrow disease that slowly progresses. The disease usually occurs in middle aged or older individuals and rarely occurs in children. In CML, an unusually high number of blood stem cells become granulocytes. These granulocytes, also called leukemia cells are irregular in shape and do not develop into healthy white blood cells. Eventually, they concentrate in the blood leaving no room for healthy cells which may lead to infection, anemia, or bleeding. The typical signs of CML include fatigue, fever, night sweats, and weight loss (6).
Progress and innovation are key components to discover new possibilities to fight against childhood cancer. To begin with, my interest in healthcare sparked when I was diagnosed with childhood sarcoma cancer at the age of seven. As a cancer
Pediatric Oncology is at the heart of many organizations. There are many financial and emotional burdens associated with a loved one having cancer, and thanks to these foundations parents and children can sleep a little bit better at night knowing that someone has their back. Some of the more prominent groups that have an impact here in our community are: Alliance for Childhood Cancer, Bear Necessities Pediatric Cancer Foundation, CURE Childhood Cancer, and National Cancer Institute (Mccaul). These are organizations that make an impact in the lives of the children battling cancer and their families. Whether an organization has been started in memory of a loved one or to support a college or hospital, organizations like those listed above have
Leukemia like any other cancer is devastating especially when it affects children and especially when they are too young to understand most of what is happening to their bodies. Facts like these are what should be used to motivate researchers and caregivers to help to make the process of treatment and care for patient dealing with disease one that is pleasant and supportive. The research should be taken seriously and it is hoped that in the future a cure can be found and the cause of the disease can be explained. It is also hoped that achievements like those can give families who are coping with disease or who have lost loved ones to the disease can find closure and solace in knowing that other may not have to go through what they have.
- Acute lymphoblastic leukemia (ALL): is a cancer of the bone marrow and the blood that progresses rapidly without treatment. This cancer is very common in children 1 to 19 years old. ALL affects the blood cells and immune system. It is very important to start treatment as soon as possible after diagnosis.
Aplastic Anemia is a form of cancer that affects the bone marrow. Bone marrow is a soft tissue that is located on the inside of larger bones. This disease I rare and is not restricted for any gender. Aplastic Anemia occurs when the bone marrow stops producing enough red blood cells, white blood cells and platelets for the body. Platelets are another form of cell that do not contain a nucleues. They circulate in the blood and keep us from bleeding. When the marrow produces these cells, the cells are normal in the way they function, but the marrow does not produce enough of the cells in order for the body to function properly. The word Aplastic actually means “a failure in development”.This disease was first discouvered in 1888 by Dr. Paul Ehrilch. He discouvered this disease after he studied a case where a preganant women died of bone marrow failure. In 1904 this condition was classified as Aplastic Anemia. The causes of this disease are un known. Risk factors of this condition tthat can increase your chnace of Aplastic anemai include exposure to envoirnmental toxins, paint , oil and coal emmsiosns, industrial soilvents, certain viruses or medications, medications used to treat rheumatoid arthiritis,bone marrow diseases and preganancy. This disease can be inhearited or caused by envoirnmental substances. When Aplastic anemia is heriditary it is less comon. Heriditary Anemia is caused by the genes being passed down from parent to child. People who have heriditary anemia have other development or genetic abberants. Faconi is the name used when aplastic Anemia is herediatary. Children with abnormal chromosomes are likely to inherit this condition. One who has herediatary Aplastic Anemia will have abnormalities in...
...essive episodes (CareNotes). As chemo is administered, patients may aquire other issues, such as a loss in appitite, less energy, sores in the mouth, pain throughout the body, an increased heartbeat, coughing or breathing issues, and confusion (CareNotes). According to CareNotes, patients must stay away from people that are sick, due to a decreased immune system, and they must drink a lot of water to stay hydrated.
Steen, Grant R. and Joseph Mirro. Childhood Cancer: A Handbook From St.Jude Children's Research Hospital . Cambridge, MA: Perseus Publisher, 2000.
Kids are meant to be happy, play outside, go to school, and have fun. They aren’t meant to sit in hospitals, losing weight by the pound, carrying around IV poles filled with poison. It’s ridiculous and immature that we don’t have a cure for childhood cancer. The only “treatment” that we have is chemotherapy- a chemical that seems to help fight off cancer. Chemo doesn’t just fight off cancer cells though- it fights off healthy cells in your blood, mouth, digestive system, and hair follicles. The most frustrating thing about childhood cancer is that only 4% of federal funding is exclusively dedicated to childhood cancer research. It is true that more adults get diagnosed with cancer than kids, but does that mean that adults are 96% more important than children? The average age of diagnosis for an adult with cancer is age 67, and the average number of years lost is 15. 15 years are definitely many years, but not that many compared to the average number of years lost for a child- 71. Also, age 67 is a lot older than the average age of diagnoses for a child- age 6. At least the adults get to grow up and have the ability to even have cancer- some of these kids can’t even get through a fifth of their lives.
The most noticeable signs of lymphedema of the affected limb or body area include swelling on part of or all of the limb or area, a heavy feeling, tightness, difficulty moving or bending the hand, wrist, foot, or ankle, achiness, recurring skin infections, fatigue, and thickening and hardening of the skin. Swelling for lymphedema ranges from non-visible, people can see slight swelling with a heavy feeling; reversible, swelling at the distal end of the extremity and it reduces upon elevation; irreversible, fibrosis is present with thickening and one extremity is bigger than the other; and severe, limbs become abnormally larger than the rest of the body. In the course of cancer treatments lymphedema might not occur until months or years later. People with this condition are more at risk for developing cellulitis, lymphangitis, or edema may worsen over time. If left untreated cellulitis can lead to septicemia, abscesses, ulcerations, and/or
Infant Leukaemia: A Report From The Children's Oncology Group." Paediatric & Perinatal Epidemiology 25.6 (2011): 559-565. Academic Search Premier. Web. 28 Jan. 2014.
Kanwar, V.S. (2013, Sep 16). Diseases & Conditions - Medscape Reference. Pediatric Acute Lymphoblastic Leukemia. Retrieved January 13, 2014, from http://emedicine.medscape.com/article/990113-overview#a0156
"Late Effects of Treatment for Childhood Cancer (PDQ®)." The Canadian Press n.d.: n. pag. - National Cancer Institute. Web. 14 Mar. 2014.
Chemotherapy, which is a cancer treatment that uses drugs to target and destroy the cancer cells, is the most-common route of a patient diagnosed with Leukemia. It can come via pill, cream on your skin, or even an injection. Although this treatment sounds harmless, it can actually start affecting other parts of your body that were otherwise healthy, and can also cost a fortune. Another treatment option is radiation. This treatment option uses high-energy waves to destroy cancerous cells. A disadvantage of this procedure is that it has a likely-chance of killing normal cells which are not doing any harm to the body. Side effects will depend on certain situations. The third procedure is bone marrow transplant. As described earlier, the bone marrow transplant has to come from a relative or someone with the same body structure as the patient. Any donor must be healthy and willing. The bone marrow is crucial to your body,and if anything goes wrong, it could affect the whole body. Each of these solutions for a child with cancer have pros and