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Research thesis on brain cancer
Brain cancer paper
Research thesis on brain cancer
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Shannon Brown
Mr. Pontes
English 12 Honors
19 May 2014
According to SEER Statistics, 23,380 people are estimated to get a brain or nervous system cancer diagnosis. Out of those people, 14,320 people are estimated to die from their brain or nervous system cancer diagnosis (National Cancer Institute). Cancer is a type of dangerous tumor, or a buildup of extra cells that form a mass of tissue, that can be life threatening (National Cancer Institute). The term for a tumor that is cancerous is a malignat tumor, whereas a benign tumor does not contain cancer cells (National Cancer Institute). According to the National Cancer Institute, the causes of brain cancer are unknown, but risk factors include family history and excessive radiaton exposure. Although they are not always due to a brain tumor, comon symptoms include headaches, nausea, speech, hearing, vision, and mood changes, problems with balance and mamories, seizures, and numbness in arms and legs (National Cancer Institute). MRI and CT scans as well as surgical biposies (or the removal of part of the tumor to be examined) are used to diagnose brain cancer (National Cancer Institute). Different types of treatment options include radiation therapy, surgery to remove the tumor, and chemotherapy. According to Charles Davis, MD, PhD and Nitin Tandon, MD of WebMD.com, chemotherapy is “ the use of powerful drugs to kill tumor cells”. There are a few different types of chemotherapy, but all of which bring out the same kinds of side effects. Although the physical side effects of chemotherapy are commonly known, few people know of the emotional toll chemotherapy can take on a patient and his or her family as they go though this process.
The different types of chemotherapy include...
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...essive episodes (CareNotes). As chemo is administered, patients may aquire other issues, such as a loss in appitite, less energy, sores in the mouth, pain throughout the body, an increased heartbeat, coughing or breathing issues, and confusion (CareNotes). According to CareNotes, patients must stay away from people that are sick, due to a decreased immune system, and they must drink a lot of water to stay hydrated.
Although the physical side effects can be pretty terrible to deal with, the emotional side effects for a patient getting chemotherapy can be just as bad, if not worse. Jason Corinha, age eighteen, was diagnosed with Langerhans Cell Histiocytosis (LCH) at age thirteen. LCH is a rare form of cancer where the tumor is made up of white blood cells. This tumor grows in between the brain and the skull, causing a great deal of pressure and pain in the head.
Popular beliefs and opinions of the masses in society often become societal norms. Challenges to these societal norms can cause large-scale societal shifts or transitions. Examples of such occurrences include woman’s suffrage, the occupy movement, and falsified racial stereotyping. However, popular opinions, influenced by media, corporations, and members of the community, are sometimes flawed. “Welcome to Cancerland,” written by Barbara Ehrenreich, and “Beautiful Brains,” written by David Dobbs share a similar purpose of debunking common myths and stereotypes of specific social groups. Ehrenreich’s essay states that corporations and community members are popularizing the celebration of the “breast cancer sisterhood,” while stemming the drive
Glioblastoma Multiforme is the most aggressive and malignant form of brain cancer, with an average survival of less than 12 months.
Glioblastoma Multiforme (GMB) is the most common form of primary malignant brain tumor in adults. With the current standard therapy, median survival time hovers just over 12 months. This incurable disease is devastating with a median survival time of 6-8 months from time of recurrence (J10). The current standard of therapy at first diagnosis consists of surgery followed by radiotherapy with concommittant and adjuvant chemotherapy using the agent temozolamide (TMZ) (Multiple sources). In 2003, the United States Food and Drug administration approved the Gliadel Wafer (GW) for treatment of newly diagnosed GBM (C3). The monoclonal antibody Bevacizumab (BEV) was first used to treat recurrent GBM in 2005 and has a significant survival benefit for patients with grade IV glioma (E5). Many more promising avenues for new treatment have been and are currently being studied. Such areas include the use of antiepileptic drugs, using Convection-Enhanced Delivery of chemotherapeutic agents, and targeting specific molecular markers and pathways such as the epidermal growth factor receptor (EGFR), O6-methylguanine-DNA-methyltransferase (MGMT), and the PI3K/Akt/mTOR pathway.
According to the Central Brain Tumor Registry of the United States (CBTRUS), the incidence rate of all primary malignant and non-malignant brain and central nervous system tumors (CNS) for 2005 to 2009 was 20.6 cases per 100,00 (7.3 per 100,000 for malignant tumors and 13.3 per 100,000 for non-malignant tumors) (Fig. 1) [1].
Cancer is a disease in which cells multiply out of control and gradually build a mass of tissue called a tumor. There has been a large amount of research dedicated to the treatment and cure of cancer. Several types of treatments have been developed. The following are just some of the major examples of cancer therapy: surgery, chemotherapy, radiation therapy, biologic therapy, biorhythms, unconventional treatments, and hyperthermia. Each type of treatment is discussed in detail below.
A Brain Tumor is a mass of abnormal cells that vary in size. They can also be classified as Benign or Malignant. Benign Tumors are non-cancerous, and have definite borders that make removal of the entire mass possible. On the other hand, Malignant (Cancerous) Brain Tumors spread, aggressively invading nearby tissue, and have a higher chance of recurring after surgical removal.
For cancer patients there are several treatment options. Surgery can remove cancerous tumors, chemotherapy uses drugs for treatment, and radiation therapy. The doctor in charge of the patient’s treatment may also choose to use radiation therapy. “Radiation
I was a child when my aunt got sick, and my fascination about the field of medicine began. She had brain cancer. While I watched the disease progress I was flooded, not only with sadness and grief, but with questions. With two psychologists for parents I had a lot of support and understanding of my feelings, but I was left curious about the medical aspect of the disease and why there was no cure. The notion that the brain could change someone’s entire personality and physical function was amazing to me. Spending a lot of time in hospitals, I observed so much about the impact of a cancer diagnosis on patients and their families, and about what happens to people through the disease process. I noticed the enormous influence that the medical professional’s
The side effects brought on by chemotherapy are very harsh on the body. These side effects occur because the chemo agents are poisonous and cancer cells and normal cells are very similar so it is very difficult to leave normal cells unharmed causing the patient to experience side effects while undergoing chemo. These side effects can include nausea, vomiting, diarrhea, hair loss, mouth sores, skin changes, and low blood counts. These side effects don't...
...effects that can come with chemotherapy such as nausea, vomiting, hair loss, fatigue, mouth sores, and more. Radiation therapy is pretty bad but not as painful with side effects. Side effects for radiation therapy are coughing, fever, fullness of chest, soreness and scaring. Many times surgery is not an option but when is it is one of the best options due to the fact there are less side effects and no strenuous treatment. One of the reasons cancer is such a bad thing is because the treatment is not good but research is taking place and working to get more effective.
The implications of becoming aware that you have been afflicted with this disease may extend far beyond just a physical condition. Learning that you have cancer can significantly affect a person’s mental, emotional, and physical health. This could cause tension in social relationships, finances, or other lifestyle choices. Becoming more anxious or depressed can considerably hinder a person’s ability to make rational decisions when it concerns their well-being. For these reasons, it is crucial for one to seek professional help for all aspects of their lives when they become aware of any serious changes.
Between the ages of one and fourteen, one of the three most common reasons for fatality is cancer (. Though the types of childhood cancers are endless, the most frequent one is leukemia, which is a cancer of the blood cells. This occurs when the number of white blood cells is abnormally high and the number of red blood cells and platelets are abnormally low. In a normal blood sample the red blood cells greatly outnumber the white blood cells, making up about half of blood components in itself. When a patient has leukemia, the white blood cells increase greatly and the red blood cells decrease, causing an inability to transfer the necessary amount of oxygen throughout the body. In youth patients there are two major types of Leukemia; the ...
How does one see the symptoms for childhood cancer? First one must know that there are many different types. There are forty different types of children’s cancer, including: Leukemia, Lymphoma, Sarcomas, cancers of the nervous system, liver cancers, kidney cancer, and more. Out of these cancers, the two most common childhood cancers are Leukemia, and brain tumors. What is leukemia? It is a cancer in which the bone marrow and other organs that produce blood produce and increased amount of immature or abnormal white blood cells. The symptoms of leukemia are paleness, excessive bruising, pain in the joints, and fatigue. Brain tumors are formed when a massive amount of cells are produced on the brain. The symptoms for this are frequent headaches, vomiting, seizures, decreased coordination, weakness, and problems concerning vision.
What exactly is Chemotherapy and why would it also kill “good” cells? Cancer could be described as the disease that sends cells out of control, rapidly multiplying the cells, until it harms the body. Chemotherapy is an effective drug treatment intended to treat individuals with various forms of cancer. Generally, this type of treatment is nonspecific, and non-molecular that uses chemical agents to break down all dividing cells. Chemotherapy, or chemo for short, destroys cancer cells, and can also cease the reproduction or spreading of these cells. Despite having apparent benefits, this type of treatment comes at a cost, presenting several disadvantages and side effects. Chemotherapy comes with a heavy burden, nausea and vomiting, diarrhea, anemia, infections, and fatigue is a few of the short-term side effects. This analysis examines chemotherapy as a type of cancer treatment, as well as evaluating complimentary and alternative medicines.
Introduction: Did you know that brain cancer that has one of the lowest success rates of all cancers? It is true, after one year after diagnosis there is a 50% survival rate, but this drastically changes to a terribly low 19% after 5 years. Brain cancer is a deadly disease where cancer and brain cells clump together to form a brain tumor (a huge lump of cancerous, and brain) flesh. Brain Tumours that are cancerous are malignant, and non-cancerous Tumours are benign. These deadly lumps of cancer can be found in the brain and spine.