Drug Act The term orphan drug refers to a product that treats a rare disease affecting fewer than 200,000 Americans. Orphan drugs help the companies that manufacture them, under the Orphan drug act. Under the act a small company can pick up a product that would be worth anywhere from $5 million to $20 million a year. The orphan drug act has helped in the development of products to treat drug addiction, leprosy, hemophilia, and rare cancers, as well as diseases most people have never heard of, such
“The carrier rate for Tay-Sachs in the general population is 1/600” (OMIM). Sandhoff Disease is a rare genetic disorder, and it is a severe form of Tay-Sachs that progressively destroys cells in the brain and spinal cord. Since its discovery and analysis of inheritance, there have been advancements of its diagnosis, treatment, research, and its support resources for affected families. Those affected individuals lose motor skills and function of other body parts. As the disease progresses they experience
Hydrocephalus is a genetic disorder commonly described as “water on the brain.” In actuality, this is a condition in which there is an excessive accumulation of cerebrospinal fluid (CSF), a clear watery fluid that surrounds the space between the brain and spinal cord, in the brain. Normally, the production together with the absorption process of CSF is specifically balanced to ensure that the brain tissue remains buoyant, that nutrients can be delivered and waste removed, and that there is a compensation
Messi the player who was diagnosed with a growth disorder. Lionel Messi overcame it and was able to become a professional soccer player. Lionel Messi and his growth disorder. A growth disorder is a disorder that prevents a child reaching their initial height (Peak 13). Nevertheless some symptoms of a growth disorder usually deals with the height or the child could be larger or smaller than other normal height children. A child with a growth disorder can grow much faster or slower than a normal child
Leigh syndrome is a fatal disorder that causes progressive neurodegeneration in mostly young kids. It was discovered in 1951 by Denis Leigh who originally named it Necrotizing Encephalomyelopathy. Leigh originally classified it based on phenotypes found in a boy who had normal development until the age of 6 months. After this the boy showed various phenotypes including optic atrophy, deafness, and bilateral spasticity. The neurological phenotypes displayed in the boy were: neuron degeneration, gliosis
EhlersDanlos Syndrome Ehlers-Danlos sydrome (EDS) is a rare inherited group of connective tissue disorders characterized by defects of the major structural protein in the body (collagen). Collagen is a tough fibrous protein that plays an essential role in binding, holding together, strengthening, and providing elasticity to bodily cells and tissues. There are six major types of EDS that I will discuss, however I will only go into detailed discussion on two of the six types of EDS. The two major
Phenylketonuria Phenylketonuria, otherwise known as PKU, is a rare genetic disease that is caused by a person’s body being unable to metabolize the amino acid phenylalanine. The disease can cause mental retardation because the build up of phenylalanine in the body. When phenylalanine is not broken down and turned in a different amino acid, tyrosine, it can create other enzyme routes that build up in the blood stream and body tissue. This can be extremely harmful to the body and its development
Bipolar Disorder: The Angel and Devil In One There was once a family; however, it was not a happy family. The mother was sick though she did not believe she was sick. She frightens her family with her explosive personality. She would shout at her children, pushing them to the edge and over to do their best. Her husband would constantly plead with her to go to the doctors and to take her medications. She never listened to him. One day when the husband returned from work, he found that his wife had
According to the World Health Organization diagnostic criteria, ALL is diagnosed when “lymphoblasts account for more than 20% to 25% of cells”(Epocrates, 2014). Symptoms of ALL can depend on which areas of the body the cancerous cells had spread to. However generalized symptoms include
Schizophrenia affects nearly about two million people in the United States, according to the SARDAA ( Schizophrenic and Related Disorders Alliance of America). People who have schizophrenia often see and hear people's voices in their mind, they believe that such people are out to get them and trying to harm them. It is difficult to separate the people who have schizophrenia with the ones that have not. Until you hear someone speak during a schizophrenic episode, then it seems like they have lost
Topic: Emperor Penguins Organization: Topically Specific purpose: To teach my audience about an overlooked species. I. Introduction A. Attention Getter Can you imagine living in a state of pure cold? Where the temperature is constantly sub-zero? How about an entire colony living in such conditions? This is the life of an emperor penguin. B. Relevance Everyone loves penguins. And if you don’t I will kindy have to ask you to leave. Just kidding, Everyone has seen movies centered around Penguins,
days at work, calling in sick more frequently. The employee seems to have trouble concentrating. The worker may be descending into an emotional tailspin. The condition of malaise that may be experienced could very well be depression. "Depressive disorders represent one of the most common behavioral health problems in the work force." In this stress-filled world that we live and work in, it is important that today’s workforce managers and supervisors recognize the signs and symptoms of depression
People check things twice, but what if you feel the urge to repeat things ten times. Obsessive Compulsive Disorder is an anxiety disorder that is characterized by obsessions and compulsions. People use obsessions and compulsions to relieve their anxiety. Without treatment obsessions and compulsions can eventually take over a person’s life. These obsessions and compulsions can be treated with medication or therapy making a person’s life more bearable. Dr. Dorothy Grice had said in an interview with
There are many disabilities that affect the Musculoskeletal System. One disability is Spina Bifida, which is a series of spinal cord defects caused by abnormal fetal development. We don’t know all the causes of spina bifida. Genetics and the environment may play a role in causing spina bifida. Spina bifida can range from mild to extreme. Some people may have little to no disability while others people may be limited in the way they move. Some people may even be paralyzed or unable to walk or move
Attention Hyperactive Deficit Disorder “You know how it feels when you’re leaning back in your chair and it’s just about to fall over? I feel like that all the time!” This is how a person affected with Attention Deficit Hyperactive Disorder (ADHD) feels every day. ADHD refers to a family of related disorders that interfere with an individual's capacity to regulate activity level, inhibit behavior, and attend to tasks in developmentally appropriate ways. Some statistics: 75% people with
paranoid schizophrenia. This fictional character in Ken Kesey’s One Flew Over The Cuckoo’s Nest struggles with extreme mental illness, but he also falls victim to the choking grasp of society, which worsens Bromden’s condition. Paranoid schizophrenia is a rare mental illness that leads to heavy delusions and hallucinations among other, less serious, symptoms. Through the love and compassion that Bromden’s inmate, Randle Patrick McMurphy, gives Chief Bromden, he is able to briefly overcome paranoid schizophrenia
Its no accident that off-spring resemble their parents. Deoxyribonucleic acid or DNA, located within each cell nucleus is a special chemical, that determines our genetic inheritance in a very orderly way. Under the microscope DNA looks like a mass of tangled threads which consist of tiny subunits called genes. Genes carry instructions, sometimes called the blueprint of life, for various characters like hair color, height, eye color. Our genes are received from both mother and father, half from each
form, which affects people at approximately age 60. Most people diagnosed with this disease do not live past five years of its onset(1). Currently, not much is known about Binswanger's Disease; in many ways it resembles various other neurological disorders making it difficult to diagnose. The trademark of this disease is damage to the blood vessels in the deep white matter of the brain(1),(4),(5). The pons, basal ganglia, and thalamus are typical sites for these lesions(5),(7). A Magnetic Resonance
As humans, we are all fascinated by the idea of love. We believed that only love can save us from our emptiness and brokenness. The feelings of being with someone you love is astonishing, because the mental connection is rare. The desire of wanting to give everything and care for that person is usually valid in dating. One feels butterflies in their stomach, their heart races when one sees their significant others, flushed cheeks, disorganized thoughts etc. But what if the feeling of heavy breathing
the victim and their families. In the beginning stages, the child grows slowly without any weight gain resulting in the appearance of aging. The child's life is also affected due to the symptoms, tests, and treatments they experience. Progeria is a rare ailment in adolescents that stems from a specific genetic abnormality for which there is no current cure, and it dramatically impacts the life of the individual physically, mentally, and emotionally. The main cause of Progeria is a genetic mutation