Is Clopidogrel effective in the prevention of secondary stroke in a 65 year-old male who recently had a stroke? Ischemic Stroke is caused due to a blood clot in an area of the brain, leading to loss of neural function if last for more than 24 hours. In the United States, ischemic stroke affects 2.7% of men and 2.5% of women of age range 18 years and older. In addition, it has reported that annually about 610,000 and 185,000 of new strokes and recurrent strokes cases occur in US1. Moreover, it has
Figure 3. This figure shows the mechanism of action of Clopidogrel (Guzman, F. 2008). Clopidogrel inhibits aggregation for 7 to 10 days which is the average lifespan of a platelet, it produces a dosage dependent effect which begin 2 hours after a single dose and the inhibition is approximately 40% to 60% in adults (L. Buck, M. and D, P., 2010). • Pharmacokinetic Implications ( a description of the mechanism of the patient response) Clopidogrel is taken orally and is rapidly absorbed having a bioavailability
of these effects are only apparent at much higher doses. CLOPIDOGREL An ADP receptor antagonist that competitively inhibits ADP from binding to platelet receptor, preventing ADP-mediated up regulation of glycoprotein (GP) IIb/IIa receptor, again blocking amplification of platelet aggregation. o Direct comparison of Clopidogrel may indicate that it is a slightly more effective Antiplatelet drug than aspirin. o More importantly, Clopidogrel is routinely used In the treatment of acute coronary syndrome
Abdellatif Elmansouri English Composition 1 Jesse Holcomb March 19, 2014 Tobacco Shouldn’t Be Banned Tobacco is one of the most popular products in the United States and one of the most used drugs in the world, especially in the form of cigarettes. Even though many countries put restrictions on using tobacco, the numbers of people that smoke everyday has increased, even when they know it is harmful to their health. Smokers make up approximately 26% of the United States population, so a ban of this
There is research that suggests that alcohol and cigarette usage can prevent brain altering diseases in elderly years, even though substance abuse is directed linked to dementia. Alcohol consumption can decrease the risk of dementia. Tobacco products have many health benefits. However, reducing alcohol consumption can prevent dementia. Making the conscious decision to abstain from alcohol can positively impact brain health dramatically. Cutting back on cigarettes and tobacco products lessens the
In the years of 2007 to 20112 the U.S. Centers for Disease Control conducted a survey on prescription drug usage. They reported that 49% of the people in the U.S. had taken at least one prescription drug in the past months, and around 22% had taken more than one prescription drug in the same time period. This percentage of people was significantly larger than the same research data founded over a decade earlier. Prescription were made for many important medicinal reasons that span in severity like:
implantation.EuroIntervention 2009;5:78–85. 27-Ussia GP, Scarabelli M, Mulè M, et al. Dual antiplatelet therapy versus aspirin alone in patients undergoing transcatheter aortic valve implantation.Am J Cardiol 2011;108:1772–6. 28- Aspirin Versus Aspirin þ Clopidogrel Following Transcatheter Aortic Valve Implantation: the ARTE trial. 2012. Available at: http://clinicaltrials.gov/ct2/show/nct01559298?term¼nct01559298&rank¼1.Accessed May 30, 2012. 29-Jean-Philippe Collet, Gilles Montalescot, Antithrombotic and
Goals and Objectives for Acute Myocardial Infarction In order to know what myocardial infarction is, it is important to know when to diagnose the condition and to do it as soon as possible. It is vital to be able to know the sign and symptoms for a myocardial infarction and how to treat them to prevent any further damage to the myocardium. Since damage can occur to the myocardium, heart muscle, one of the goals is to save as much of the heart muscle as possible through procedures to be able to open
AN ELDERLY MALE WITH NEUROLOGICAL DETERIORATION: A CASE REPORT OF RECURRENT STROKE WITH WORSENING PARKINSON DISEASE. Ahmad Sahli Mahzuz Bin Ismail Abstract Stroke is the third most common cause of death (11% of all death in UK) and the leading cause of adult disability worldwide. Stroke rates increases with age but one quarter of all stroke occur before the age of 65. It is important to differentiate between stroke and transient ischemic attack
Patient with chronic stable angina may develop UA or been the first manifestation of CAD. Unlike chronic stable angina UA is unpredictable and represents an emergency. Nitroglycerin, morphine and O2. Blood thinners (antiplatelet drugs Aspirin, clopidogrel. heparin (or another blood thinner Nursing interventions in the initial included pain assessment and relieve, physiological monitoring promotion of rest and comfort, alleviation of stress and anxiety and understanding the patients emotional and
Overview of medical and pharmacological Management Pharmacologic management of PAD typically involves statins, which help manage cholesterol, and antihypertensives to decrease blood pressure. Anti-platelets including aspirin (for later stages) and clopidogrel (Plavix) can be used to reduce the risk of vascular accidents in patients with PAD.4 Cliostazol (Pletal) and pentoxifylline (Trental) are both newer drugs for treating intermittent claudication; they inhibit platelet aggregation and dialate arteries
Every year tobacco is responsible for over 480,000 deaths. That includes people who have died from secondhand smoke. When statistics like this exist it is hard to understand why tobacco is still legal. This number increases every year that passes and most people believe it isn’t shrinking anytime soon. Tobacco should be banned because it’s deadly to not only the users, it’s highly addictive, and the tobacco industry is corrupting information promoting its harmful product. Society shouldn’t have to
medication and to monitor the liver function throughout the drug therapy. If the patient develops muscle tenderness, the nurse will need to assess CK levels in the patient (Deglin, Vallerand and Sanoski, 2014, p. 642). 75 mg by mouth at bedtime of Clopidogrel, which is an antiplatelet agent, is being used to reduce atherosclerotic events. When giving this medication, the nurse needs to assess for symptoms of stroke, PVD, or MI periodically during treatment. Also, the nurse needs to monitor for signs
“Extreme high heart rate, ‘cold’ sweat, and dizziness,” is what Kevin Olinger, a person living with atrial fibrillation (afib), experiences during an afib episode (1). Atrial fibrillation, a very serious heart arrhythmia, is found in over two million people living in the United States (2 What is 1). According to Gary Riddle, doctor at Memorial Hospital Health Care Center, he cares for roughly 40 patients diagnosed with afib each year in Ferdinand, Indiana (Riddle 1). People the age of 40 and over
Myocardial infarction and stroke are both very destructive to the human body especially in terms of possible organ and tissue damage. This essay will discuss topics involving MI and stroke and various treatments, risk factors, causes, and other items surround the two. The causes of MI include, but are not limited to, bad cholesterol (i.e. high levels of low-density lipoprotein (LDL) cholesterol) leading to increased risk of arterial occlusion, high amounts of saturated fats leading to an increased
Stroke Medications and Treatment “Time is brain” is the repeated catch phrase when addressing the treatment and management of stroke (Saver, 2006). Access to prompt and appropriate medical care during the first few hours of stroke onset is critical to patient survival and outcomes. Recent changes in the guidelines for acute stroke care released by the American Heart Association (AHA) and the American Stroke Association (ASA) have improved patient access to treatment. Stroke treatment now follows
People trust their physicians to know how to diagnose what is wrong with them using diagnostic skills which include patient interview, medical tests and physical observation. We have become accustomed the mindset that there is a pill to fix what is making US feel bad. Doctors in the United States of America a lot less than 20 minutes for each patient, and this time most people would never think to ask the physician if there is more than one way to treat their illness. In fact most people do not ask
Introduction and patient profile This assignment is a case study that aims to explore the biospychosocial impacts of a myocardial infarction on a service user. It will focus on the interventions used by healthcare professionals throughout the patient’s journey to recovery. To abide by the NMC’s code of conduct (2015) which states that all nurses owe a duty of confidentiality to all those who are receiving care, the service user used in this case study will be referred to as Julie. Julie is a 67 year
Chapter-2 Efficient ZnO NPs catalyzed Friedlander annulations in the synthesis of diverse quinolin-2(1H)-ones 2.1.1 INTRODUCTION OF QUINOLINONES AND QUINOLINES The quinolinone and quinoline ring is highly prevalent in natural compounds. There are synthetic and potential agents, which show various pharmacological properties (Priya et al., 2012). Quinolinones are important structural intermediates for synthesis of functionalized quinolines (Baston et al., 2000). Quinolines have demonstrated various