Wait a second!
More handpicked essays just for you.
More handpicked essays just for you.
Discuss the physiological and psychological effects of LSD
Research paper on lsd
Discuss the physiological and psychological effects of LSD
Don’t take our word for it - see why 10 million students trust us with their essay needs.
LSD (lysergic Acid Dyethilamide)
A Swiss chemist named Dr. Albert Hoffman first produced lysergic acid Diethylmide –or best known as LSD in 1938 (Dye, 1992, p. 2). Hoffman discovered the drug while trying to synthesize a new drug for the treatment of headaches. He obtained the lysergic acid from the parasitic fungus that grows on rye plants known as ergot. From the lysergic acid, he synthesized the compound LSD. He used the compound to test for its pain killing properties on laboratory animals. Being that appeared totally ineffective, the bottle of LSD was placed on a shelf and remained untouched for five years.
On April 16, 1943, Dr. Hoffman decided to do further research with the LSD compound (Dye, 1992 p. 5). While handling the drug, he accidentally ingested an unknown amount. Then he experienced the world’s first LSD trip. About eight hours later Hoffman drifted back into normal reality and the Psychedelic Revolution was born. (Encarta 98) Three days later, in an attempt to prove that the previous episode was indeed caused by the ingestion of LSD, Dr. Hoffman ingested what he thought would be a small quantity of LSD, 250 micrograms. In actuality, this is approximately five times the dosage necessary to produce heavy hallucinations in the average adult male (Solomon, 1964, p. 34). The drug produced effects that were much more intense than the first time Hoffman took the LSD. He noted that he felt unrest, dizziness, visual disturbances, a tendency to laugh at inappropriate times, and a difficulty in concentration (Dye, 1992, p.7). Dr. Hoffman’s condition improved six hours after taking the drug, although visual disturbances and distortion continued.
LSD was first shipped to the United States in 1949 (Solomon, 1964 , p. 54). American scientists tested LSD on animals to learn of its effects. It produced dramatic behavior changes in all animals investigated.
During the 1950’s, experimentation of LSD on humans began (Solomon, 1964, p. 56). Since there were few restrictions on using humans for experimentation at the time, scientists were free to administer the drug widely, hoping to find some useful therapeutic value for the drug. Because of Hoffman’s LSD account of depersonalization produced by the drug. Early studies were done using the drug to treat various psychiatric disorders. It was felt that if a person could "step outside" themselves and...
... middle of paper ...
... other intoxicants, or while a person is in the presence of someone under the influence of LSD. Flashbacks have been known to cause psychotic and suicide reactions have been recorded as insanity.
LSD was not only restricted to big cities such as the streets of Haight and Ashbury of San Francisco. From Ken Kesey and his Merry Pranksters to the Beatles’ song ‘Lucy In The Shy With Diamonds’, LSD was gaining national recognition and had reached suburbia by the mid 1960’s. LSD inspires art, music, fashion, and culture for a generation. "Psychedelic", a word invented by scientist Dr. Humphrey Osmond to indicate the mind altering or mind expanding properties of hallucinogenic drugs, became a household term in the 1960’s. Aldous Huxley (b.1894-1963), writer of the critically acclaimed books Brave New World (1932) and The Doors of Perception (1954), was an advocate of the usage of hallucinogens. Huxley researched and experimented with mescaline and later related his studies on mescaline to LSD. In his usage of mescaline, Huxley experienced a change in every day reality. Unlike mescaline users before him, Huxley had no fantastic visions, saw no landscapes or geometrical figures.
During a visit to Mexico, Gordon Wasson, a mycologist, discovered the use of psilocybin mushroom in spiritual ceremonies by Indian tribes. Upon experiencing the spiritual and hallucinatory effects of the mushroom, Wasson returned to the area accompanied by an experienced mycologist, Roger Heim, who managed to cultivate the mushroom once in France and send samples of it to the scientist who had discovered lysergic acid, Albert Hoffman. From the mushrooms, Hoffman successfully isolated two compounds which he further named psilocybin and psilocin. Analogs of these compounds were further synthesized and were employed mainly for psychotherapeutic uses. Many tests on psilocybin were made at Harvard University in the early 1960’s. However, along with LSD, psilocybin became a scheduled substance in 1970, making it illegal. During this time, psilocybin mushrooms became a part of the psychedelic and hippy movement and were used for recreational and spiritual purposes. Research on psilocybin ended in the late 1980’s because of strict rules imposed by the government but recently scientist have started researching on this chemical once more.
Erika Dyck provides the reader and interesting view of early historical psychological research on LSD, lysergic acid diethyl-amide. This book is composed of Dyck’s scientific interpretation and dissection of earlier psychedelic psychiatry research by Humphry Osmond, and Abraham Hoffer. A Swiss biochemist named Albert Hofmann dissolved a minimal amount of d-lysergic acid diethyl-amide in a glass of water and digested this new synthetic drug in April 1943. Three hours later he begins to feel dizzy and his vision was distorted. Hofmann recollects this as a surreal journey as if what he saw was created by the famous paintings of Salvador Dali unexplained carnivalesque or at some moments even nightmarish hallucinations. The drug began gaining support from pharmaceutical companies as something that can possibly be beneficial for future scientific study. Saskatchewan soon became one of the epicenters harvesting break through biochemical innovation and experimentation with LSD from the 1950s to 1960s.
In 1967 the Beatles were in Abbey Road Studios putting the finishing touches on their album Sgt. Pepper's Lonely Hearts Club Band. At one point Paul McCartney wandered down the corridor and heard what was then a new young band called Pink Floyd working on their hypnotic debut, The Piper at the Gates of Dawn. He listened for a moment, then came rushing back. "Hey guys," he reputedly said, "There's a new band in there and they're gonna steal our thunder." With their mix of blues, music hall influences, Lewis Carroll references, and dissonant experimentation, Pink Floyd was one of the key bands of the 1960s psychedelic revolution, a pop culture movement that emerged with American and British rock, before sweeping through film, literature, and the visual arts. The music was largely inspired by hallucinogens, or so-called "mind-expanding" drugs such as marijuana and LSD (lysergic acid diethylamide; "acid"), and attempted to recreate drug-induced states through the use of overdriven guitar, amplified feedback, and droning guitar motifs influenced by Eastern music. This psychedelic consciousness was seeded, in the United States, by countercultural gurus such as Dr. Timothy Leary, a Harvard University professor who began researching LSD as a tool of self-discovery from 1960, and writer Ken Kesey who with his Merry Pranksters staged Acid Tests--multimedia "happenings" set to the music of the Warlocks (later the Grateful Dead) and documented by novelist Tom Wolfe in the literary classic The Electric Kool-Aid Acid Test (1968)--and traversed the country during the mid-1960s on a kaleidoscope-colored school bus. "Everybody felt the '60s were a breakthrough. There was exploration of sexual freedom and [...
Lee, Martin A. Acid dreams: The Complete Social History of LSD: The CIA, the Sixties, and Beyond. Grove Press. 1985.
5)Groff, S. Realms of the Human Unconcious: Observations from LSD Research. Jeremy Tarcher Inc., LA. 1980, pp 87-99.
Sildenafil Citrate, more commonly known by the brand name Viagra, has become one of the most commonly prescribed drugs in America. Viagra is used to treat erectile dysfunction, also known as impotence. Erectile Dysfunction is best defined as the inability to maintain an erection necessary for sexual satisfaction. Sildenafil has been shown to be effective for a "broad range ED patients, including those with a history of mellitus, depression, … hypertension, diabetes, …and spinal chord injury" (Sildenafil Citrate, par. 29).
The controversial purchase of LSD by the USA in 1951 was the first step in one of the CIA’s secret operations called MK-Ultra. This was a method to test the methods of experimentation of the LSD through mind control throughout the 50’s and 60’s due to the tense situation during the Cold War. But this wasn’t the full origin of this type of experiment, no. “Dr. Joseph Mengele of Auschwitz notoriety was the principal developer of the trauma-based Monarch Project and the CIA’s MK Ultra mind control programs” (Adachi, 2005). This first project, MK-Ultra, was the fundamental value project of all the future mind-control experiments that were to follow in the future of humanity.
A psychedelic drug is one that alters the brains perception and cognition. Drugs of this sort can cause visual hallucinations. People have said it feels as though everything is alive, breathing, dancing. Of course, like any drug, there is the possibility of having a “bad trip.” This is where things seemingly go wrong. The person tripping feels trapped, frightened, and extremely uncomfortable. The
A very minute does can significantly alter ones perception to the point of hallucination. Hallucination is when a person hears, or sees thing that don’t really exist. LSD is the most potent hallucinate. Approximately 100 times stronger than psilocybin, and 4000 times stronger than mescaline.
Hofmann, A. (1970, January 1). The Discovery of LSD. The Discovery of LSD. Retrieved May 12, 2014, from http://www.psychedelic-library.org/hofmann.htm
These may include sleeplessness, trembling, and raised heart rate, and blood pressure. LSD users may feel several emotions at once (including extreme terror), and their senses may seem to get crossed, giving the feeling of hearing colors and seeing sounds. Even a tiny speck of LSD can trigger these effects. Many LSD users have flashbacks: sudden repetitions of their LSD experiences, days or months after they stop using the drug. LSD has a slightly bitter taste.
“Of all the Buddhist groups in America, those focusing on meditation have been most attractive to young people from the drug scene, and it is these groups that have taken the strongest stand against drug use. The psychological literature as well as the literature on Zen abounds in descriptions of the altered states of consciousness experienced under the influence of LSD-25 and other hallucinogenic drugs. Descriptions of these drug-induced states often compare them with the experience of satori or enlightenment which may result from Buddhist meditation. Frequently the opinion is expressed that, under certain circumstances, the LSD experience is a satori experience. ”
Nichols, D. E., & Chemel, B. R. (2011). LSD and the serotonin system's effects on human
C.S. Lewis’s The Chronicles of Narnia are often linked to his Christianity and how he portrays his faith through his characters. Because early Christianity portrays women as less than men, many believe that Lewis expresses his ideas of gender inequality throughout his writings. The Chronicles of Narnia comprises of seven stories that follow different characters and their experiences in the land of Narnia; the first novel that was written was The Lion the Witch and the Wardrobe in 1950. Throughout the novel The Lion the Witch and the Wardrobe, C.S. Lewis’ female protagonists are strong developed characters that reflected the new ideas of gender roles and equality in the 1950s.