A pathogen is anything that causes disease such as:
• Bacteria
• Virus
• Fungi
Organisms that cause disease can variety the ordinary cold to food poisoning to meningitis. They can spread in various ways such as by contacting with body fluids, consumption of undercooked food, or swimming in dirty water. In many countries surveys have took place to see the amount of disease spread by waterborne pathogens. One of the most way pathogens are spread is through personal contact.
Life Cycle of Pathogens
Bacteria
Virus
Fungi
The Life Cycle Of Tuberculosis
TB, tuberculosis spreads when a person is affected by this disease such as coughs or sneezes and the air is inhaled by another. A person with tuberculosis will suffer the following 5 stages:
Step 1: On set (1-7 days)
The bacteria are gasped in a process of air and overcome by alveolar macrophages. In some cases the bacteria’s are able to reproduce and the new pledge can harm the victim. Furthermore, Tuberculosis spreads when the mycobacterial enters alveolar mycobacterial.
Step 2: Cooperation (7-21 days)
If the bacteria does not die in the early stage, the bacteria can reproduce and until the macrophage burst. The bacteria will enter the alveolar macrophage. In addition the macrophage combine with blood and it will engulf the bacteria in an independent manner.
Step 3: Initial Caseous Necrosis (14-21 days)
Moreover, the next process of this disease starts when the reproduction of the bacteria slows. As the bacteria reproduce, the growth slows because they kill the surrounding and goes out of the cell to spread within them. In this state the bacteria can no longer reproduce but they can stay alive.
Step 4: Tissue Damaging and Macrophage Starting Response (After 21days...
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... infection and virus replication occurs in 6 main steps.
1. Adsorption - virus binds to the host cell.
2. Penetration - virus injects its genome into host cell.
3. Viral Genome Replication - viral genome replicates using the host's cellular machinery.
4. Assembly - viral components and enzymes are produced and begin to assemble.
5. Maturation - viral components assemble and viruses fully develop.
6. Release - newly produced viruses are expelled from the host cell.
Conclusion
Finally, Tuberculosis spreads by micro-bacterium which is contagious. It spreads by victim who spits coughs, sneezes or shouts, the bacteria enter the body of others. On the other hand, HIV/AIDS spreads through unprotected sex if one partner suffers this virus. Even if one drop of the fluids such as semen vaginal fluid or blood enters the partners body, this virus will eventually affect them.
Paul Farmer was born in Massachusetts in 1959, went to Harvard Medical School, became a doctor, and ended up living and working in Haiti. He co-founded an organization in 1987 called Partners in Health (PIH). The philosophy behind the organization is that everyone, no matter who or where has a right to health care. Paul Farmer and PIH have already made amazing progress in Haiti, Peru, and several other countries, helping people get the care they need. PIH’s website lists a detailed history of they and Farmer’s work in Haiti. When Paul Farmer first came to Cange, Haiti as a medical student in 1983, the place was in shambles. In 1956, a dam was built on the Artibonite River, flooding the village and forcing the residents to move up into the hills. Many of these displaced villagers were still essentially homeless after nearly thirty years, and had little access to quality health care. With the founding of the Zanmi Lasante clinic later in 1983, Farmer and his friend Ophelia Dahl set the people of Cange on the road to recovery by providing access to doctors, medicine, and emergency care, all completely free. (“Partners”) One of Farmer’s focuses was on tuberculosis (TB) and has had much success on this front. Through new studies and methods such as active case finding and community health workers, as well as his work with multidrug-resistant TB, Paul Farmer has revolutionized treatment of tuberculosis in Haiti and around the world.
Other ways hepatitis A can be transmitted from person to person are through direct contact with an infected person, such as sexual contact, and sharing of needles for intravenous drug use. Hepatitis A can also be transmitted by coming in contact with contaminated food or water. Also, foods that are uncooked or undercooked and have been contaminated with Hepatitis A can transmit the virus. Bennett, A. J.,2016; World Health Organization, 2017) Hepatitis A can affect a person of any age group.
In crowded conditions, the rate of infection is even more rapid. The diseases brought over to America were mainly spread by the respiratory method. The pathogenesis of infection is through the ingestion of contaminated food and water. Throughout Europe during the 15th century, food and water were contaminated with fecal matter and by unsanitary habits ( i.e. the lack of bathing). The traumatic route of infection is through insect and animal bites.
Others will escape from this protective mechanism to travel and settle down at alveoli (Porth, 2011). Local inflammatory reaction occurs and macrophages are cells that act as next line defense mechanism to fight with mycobacteria. First they engulf micobacteria, try to reduce their strength and ability, and kill them. In the same way they send antigen to helper T lymphocytes to initiate a cell-mediated immune response (Knechel, 2009). The infected macrophages will send produced cytokines and enzymes to breakdown mycobacteria’s protein.
It is crucial to understand that, unlike most transmissible diseases, AIDS/HIV is not transmitted through sneezing, coughing, eating or drinking from common utensils, or even being around an infected person. Casual contact with AIDS/HIV infected persons does not place others at risk. HIV/AIDS can be passed through unprotected sex with an infected person, sharing contaminated needles, from infected mother to baby during pregnancy, birth or breastfeeding, and through direct exposure to infected blood or blood
Tuberculosis is an air-borne disease, hence, it can be passed from an infected person to a healthy individual through coughing, sneezing and other salivary secretions. Tuberculosis is caused by the transfer of Mycobacteriun Tuberculosis (M. Tuberculosis) also known as Tubercle Bacillus, a small particle of 1-5 microns in diameter, due to the small size, when an infected person sneezes or coughs, about 3,000 particles are expelled. M. Tuberculosis responsible for tuberculosis is able to stay in the air for a long period of time (about 6hoursAnother way of acquiring Tuberculosis is by drinking unpasteurized milk, milk straight from cow, although this is not a common mode of transmission, it can be found in rural areas. Ingestion of contaminated cow milk transmits Mycobacterium Bovis, the animal form which is still potent enough to cause tuberculosis in humans. ). Tuberculosis transmission is affected by exposure, socioeconomic status of person, proximity, immune status of uninfected individual (%&&%&? CDC).
Tuberculosis has many forms that can invade the body. Many cures involve drugs and multiple combinations of the drugs. Drugs are used in combinations because tuberculosis can travel to different parts of the body. One of the causes for the spread of tuberculosis around the world is the emergence drug- resistance strain. Tuberculosis can become resistant to most, if not all, of the drugs that are used to treat tuberculosis.
Pathogens are a type of microorganism that spreads viral and bacterial diseases. These diseases when present in human blood and body fluids are known as blood borne pathogens, and can spread from one person to another. (Worcester polytechnic institute) The most serious types of blood borne diseases are the hepatitis B virus (HBV) and hepatitis C virus (HCV), which can cause liver damage; and HIV (human immunodeficiency virus), which is responsible for causing AIDS (acquired immune deficiency syndrome). The blood borne pathogens can be spread when the blood or body fluids (semen, vaginal fluid, breast milk, and amniotic fluid) of an infected individual comes into contact with mucous membranes or an open sore or cut on the skin of another person. Mucus membranes are located in the eyes, nose, mouth, and other areas as well. ("Bloodborne pathogens: MedlinePlus Medical Encyclopedia") Two of the most common ways that pathogens are transmitted is through the exchange of fluids during sexual intercourse or by sharing infected IV needles. (Worcester polytechnic institute)
TB germs enter the body, the immune system builds a wall around them. While TB
Viruses can be transmitted in many ways. Being in contact with an infected person will most likely transfer the virus. One can also obtain the virus through swallowing, inhaling, and unsafe sex. Poor hygiene and eating habits usually increase the risk of catching a viral infection. Contracting a viral infection is followed by adverse s...
The final stage in which the biofilm reaches critical mass and disperses bacteria which continues to colonize other surfaces, occurs in the subsequent days, weeks and months following the initial stage of biofilm formation. Bacteria that live in biofilms are difficult to treat for many reasons. Oral biofilms are varied and complex and each has its own individual micro-ecology. This micro-ecology changes as it matures and during the maturation process the density of microbes increases. The mature biofilm becomes more difficult to treat because the maturation process provides protection against antibiotics.
Tuberculosis is transmitted by inhalation of aerosols containing the tubercle bacilli. The required inoculum size for infection is usually high, but easily occurs with exposure to a patient who is currently infected. The products of dried aerosols, droplet nuclei, are particularly infectious because they remain in the air for an extended time, and upon inhalation easily move to the alveoli. The severe damage related to infection is caused by the reaction of the host. The tuberculosis infection has two phases, primary and secondary.
Recent research shows that, there are three major means by which infections can be transmitted and they include direct transmission, indirect transmission and airborne transmission (Hinman,Wasserheit and Kamb,1995). Direct transmission occurs when the physical contact between an infected person and s susceptible person takes place (division of public health, 2011). An example is a health care worker who attends to an Ebola patient, without gloves, gown and mask plus forget to wash his or her hand with soap and hot water and or a person having flu without the use of mask or washes his hand after sneezing easily passes the infection to the other through hand shake or surface touch, living the bacteria there for another vulnerable person to also touch if the surface is not disinfected with bleach. Studies makes it clear that, the spreads takes effect when disease-causing microorganisms pass from the infected person to the healthy person through direct physical contact such as touching of blood, body fluids, contact with oral secretion, bites kissing, contact with body lesions and even sexual contact. However, measles and chicken pox are said to be conditions spread by direct
There are 5 main pathways of environmental transmission of pathogens. Those are air-borne, food-borne, water-borne, vector-borne and blood-borne. Air-borne transmission refers to any disease that is caused by a pathogen and transmitted through the air. These pathogens can be spread by coughing, sneezing, stirring dust, liquid spraying, or generally any activity that generate aerosol particles or droplets. These pathogens can include viruses, bacteria, or fungi. Some common examples of pathogens that are spread via air-borne transmission are rhinovirus, hantavirus, adenovirus, and influenza, among many others (cdc.gov).
Researchers have also identified a list of other factors associated with TB transmission such as environmental, organism and host factors, but these unfortunately, are outside the scope of the present paper. 16