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Tuberculosis
Primary prevention of tuberculosis disease
Tuberculosis
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Recommended: Tuberculosis
Treatment for Tuberculosis
Tuberculosis has many forms that can invade the body. Many cures involve drugs and multiple combinations of the drugs. Drugs are used in combinations because tuberculosis can travel to different parts of the body. One of the causes for the spread of tuberculosis around the world is the emergence drug- resistance strain. Tuberculosis can become resistant to most, if not all, of the drugs that are used to treat tuberculosis.
Tuberculosis is a bacteria infection that affects many people over the world. Treatment for the disease helps people but it is limited. Vaccination is sought but, like treatment, is limited. Because of these limitations Tuberculosis spreads and kills easily. Tuberculosis can be cured by constant drug therapy.
One of the first steps to treating Tuberculosis is identifying which form has developed in the body. The two forms that could progress in the body are latent Tuberculosis infection and active Tuberculosis infection (CDC, Morbidity and Mortality Weekly Reports). Latent Tuberculosis is the dormant form of the bacteria, meaning that it is inactive and doesn?t cause an infectious reaction in the body. Even if the latent form enters the body, treatment should be sought (CDC, Morbidity and Mortality Weekly Reports). Latent Tuberculosis can become active Tuberculosis easily though, especially if the immune system is compromised by another infection, like HIV (CDC, Morbidity and Mortality Weekly Reports). Active Tuberculosis infects the body immediately. Symptoms show in the body meaning the bacteria is effecting the cells of the body. Identifying the form is important because treatment is dependent upon it. Testing for TB involves a skin test, usually within seven work-days of contact with the bacteria. Without knowing what is in the body, the drugs won?t be as effective and might even cause drug-resistance.
After diagnosing which form is in the body, treatment and therapy can begin. After the test, an infected person should inform the health-care provider with information about other people that might be infected. This will help control the spread of Tuberculosis (CDC, Morbidity and Mortality Weekly Reports). Treatment for the infected person means continual drug therapy.
Treatment for active Tuberculosis and latent Tuberculosis is usually similar because both forms of the bacteria invade multiple environments of the body. Tuberculosis originates in the lungs, because it enters through air, and sometimes spreads to other organs, called extrapulmonary Tuberculosis (World Health Organization19).
our everyday lives bacteria is constantly surrounding us, some of the bacterium that we encounter are beneficial to us but then there are the ones that are severely detrimental to our health. The way that they effect a persons body can differ from person to person. Many of the “microscopic foes” are very resilient and have a very fast reproduction rate. Not only do they reproduce quickly they sometimes seem to outsmart our immune system and not allow our bodies to fight the infection making it almost impossible to stop them. One thing that a lot if people rely on is the assistance of prescription drugs to get them better but even the drugs are not being effective and we can’t stop the pathogens from invading our personal places such as work, home, school, or anywhere. Even though modern medicine is advancing the pathogens could still get the get the best of us. The scary thing is we never know when the next pandemic or epidemic is going to arise. All it needs is some ordinary microbe to swap genes with a deadly germ to produce a “super pathogen” and it could happen to anyone, anywhere, as it did to Jeannie Brown who is from “our neck of the woods”.
Treatment: Chemotherapy is on treatment method. Most infected people benefit from the treatments. To of the best drugs for treatment are Praziquantel and Oxamniquine. The side effects are mild and transient, some of then are as followed:
Signs and Symptoms of Active Tuberculosis Mycobacterium tuberculosis (MT) is a slender, rod-shaped, aerobic bacillus which causes tuberculosis. Tuberculosis (TB) is an airborn infection which is transmitted via inhaling droplet nuclei circulating in the air. These droplets are expelled from the respiratory secretion of people who have active TB through coughing, sneezing, and talking (Porth, 2011). Some bacilli stay in the upper airway and are swept out by mucus-secreting goblet cells and cilia on the surface of the airway.
Drug resistance in mycobacterium tuberculosis (TB) has become a severe global health threat. The fight against TB is now facing major challenges due to the appearance of Multi-Drug Resistant Tuberculosis (MDR-TB) and more recently, the virtually untreatable Extensively Drug Resistant Tuberculosis (XDR-TB). MDR-TB are strains that are resistant to both top first-line drugs, Isoniazid and Rifampin, while XDR-TB are MDR-TB strains that are also resistant to any fluoroquinolone and one or more of 3 injectable drugs. With this new resistance, there emerges a great need to find new drugs that are as effective, yet bypass the problem of resistance. One method of research is to find new vulnerabilities of tuberculosis to use as new target sites of drugs. This method is highly expensive (Scheffler, Colmer, Tynan, Demain, & Gullo, 2013), and requires intense and lengthy research just to implicate the new target site. An alternative is to develop new drugs that work on the same already known target as the first-line drugs, but by a different mechanism, thereby bypassing the resistance of the TB to the drug.
...macrophage to kill bacteria that might have escaped from granuloma. Latent TB is characterized by absence of disease activity. It can be detected by TBT and Interferon-γ release assay (IGRA) and chest x-rays. The chest x-ray usually result normal due to the inactivity of the disease. TNF-α helps contain latent TB infection and keeps it from becoming active TB. Patient that have been treated withTNF antagonist are at greater risk of reactivation of LTBI to active TB
There is a tremendous positive change in TB eradication every year. However, it does not mean that TB has stopped to be a threat to public health in the United States and in the World.
Tuberculosis (TB) has various infections that can completely immobilize one's body. Its infections are varied and it generally eats away lung tissues and forms boils that releases pus. As disease proceeds, lungs would mercilessly be devoured and the victim will become pallid and fragile, coughing up blood and becoming unable to breathe. The word consumption originated from this sickness because o Infections in digestive tract can cause serious vomiting, bloody diarrhea, and acute pain. Aside from lungs, it can also infect bloodstream and even kidneys. TB can also cripple people's nervous system and their bones. Basically, it can destroy one's body completely. Surprisingly, the germ causing it (Mycobacterium tuberculosis) is extremely small.
While a patient may show signs and symptoms of Lyme Disease, the only way to confirm Lyme Disease is by taking a blood test. Once confirmed treatment is fairly simple. Patients are simply given antibiotics to kill the Lyme disease bacteria. Patients with Stage One Lyme will be given a weaker antibiotic such as amoxicillin, while more advanced cases will be given a more potent antibiotic such as penicillin. While Lyme Disease is fairly easy to treat, ten to twenty percent of patients that had Lyme Disease still may have what is called Post-treatment Lyme Disease Syndrome (CDC).
Preventing serious infections by making a person immune to the infection is called immunization. This process is usually performed by the administration of a vaccine to stimulate the person’s immune system to protect them against a subsequent infection or disease. According to the World Health Organization (2016), more than 5 million deaths were prevented annually between 2010 and 2015 due to vaccinations that were used around the world. Vaccines work with the natural ability of the human immune system to develop immunity to fight disease. When a foreign infectious pathogen such as bacteria or a virus enters the body, it multiplies and becomes an infection and in many cases, this infection leads to an illness. To understand how vaccines
Antibiotics are chemical agents that specifically target certain bacterial strains and disable the bacteria by preventing their reproduction and growth. Before or right when symptoms start occurring in a body following an infection, usually the white blood cells of the human body can cope with the infection. But when it gets past the power of WBCs, antibiotics are prescribed to prevent permanent damage to the body, permanent internal damage, sepsis or even death. The first antibiotic was Penicillin and this is a big component of modern day antibiotic medications such as ampicillin, amoxicillin and benzylpenicillin. Antibiotic resistance is when an antibiotic has lost its ability to effectively control or kill bacterial growth due to the bacterial organism changing its genetic makeup. In other words, the bacteria become resistant and continue to multiply despite the presence of therapeutic levels of an antibiotic. When a disease becomes antibiotic resistant, it is often considered incurable, and can pose a serious public health threat as a consequence.
The symptoms are spread out and take some time to occur so early treatment must be taken on first sight of the effects, tetanus injections are a relatively available resource in medicine so continuing to get booster shots ever 10 years throughout adulthood should counteract the disease. However easy suggestions to stop the infection are simple like wearing closed in shoes and covering previous wounds that may come into contact with the
Primary tuberculosis is the initial infection of the host, usually being mild and asymptomatic. A healthy person recently infected with the mycobacterium may exhibit flu-like symptoms and has no reason to suspect tuberculosis. Left untreated, the bacilli infect and multiply within pulmonary alveolar macrophages, migrating to the hilar lymph nodes. An immune response is exhibited by the T-helper cells, and inflammation develops at multiple sites. A person may test positive in the tuberculin skin test at this point, and a chest x-ray may shows opacities in the lungs.
Active tuberculosis only develops in about 10% of infected persons, remaining dormant in the rest; although the latent infection may later progress to active disease years later, especially in immune-compromised individuals. 9 Infection by MTBC may involve any organ of the body, but clinical presentation is most common in the lungs (pulmonary TB). General symptoms include fever, loss of appetite, weight loss, fatigue and severe cough with bloody sputum (hemoptysis) which may lead to death if untreated. 10 Mortality rates without treatment are high: in a study of natural history of TB in HIV-negative patients, 70% died within 10 years. 11 Tuberculosis remains a major health problem in the world...
The 1.7 HIV-related deaths a year and 990 thousand deaths from tuberculosis is an urgency
There are several ways to prevent tuberculosis. One is to control existing infections from those infected including people, pets, and cows. Unfortunately, more than 1/3 of the population has tuberculosis, making it hard to contain every case of tuberculosis. The BCG vaccine exists, but it is not very useful in countries like the US. The body’s defenses against tuberculosis are effective but fail once the immune system becomes suppressed. Antibiotics can be used to help prevent tuberculosis, but tuberculosis quickly grows resistant to antibiotics. Much needed research is being done to find a way to fight off and prevent tuberculosis.