Tuberculosis or known as TB remains a leading cause of morbidity and mortality in the world, especially in developing countries. A combination of factors including high costs, limited resources and the poor performance of various diagnostic tests make the diagnosis of TB difficult in developing countries. According to Centers for Disease Control and Prevention (2014), one third of the world’s population is infected with tuberculosis. In 2012, nearly nine million people around the world become sick with tuberculosis disease, and there were around one point three million TB related deaths worldwide. A nurse admitted a patient to the hospital with a possible diagnosis of active tuberculosis (TB). The patient was noted on admission to have a fever of 99.9°F. The patient has a cough with hemoptysis. On physical examination, the nurse notes an increased respiratory rate of 24, crackles in the lungs, and a regular heart rate of 88. Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis, in which bacteria may invade many parts of the body, such as the brain, the kidneys, and the spine. Mycobacterium tuberculosis is a rod shaped, aerobic bacterium that is resistant to destruction and can persist in necrotic and calcified lesion for prolonged periods and remain capable of reinstating growth (Porth, 2011). However, the most common target is the lungs (Wouk, 2010). The Tuberculosis bacteria severely damage the lungs that it is difficult for a person to breathe. According to Wouk, there are two main types of Tuberculosis. The first type is latent, which means a person carries the tuberculosis germ, but he or she is not sick and can not pass the germ on to the other person, and the other type is active tuberculosis. P... ... middle of paper ... ...n of purified protein derivative or PPD, which is derived from cultures of M tuberculosis (Nayak & Acharjya, 2012). According to Nayak and Acharjya (2012), a person who has been exposed to the bacteria is expected to mount an immune response in the skin containing the bacterial proteins. A positive skin test means an infection with M tuberculosis has occurred, but does not prove tuberculosis disease. However, false positive results can occur with exposure to, or disease of, nontuberculous mycobacteria (Alguire, 2009). In addition, the causes of false positive TB skin test include previous BCG vaccination, incorrect method of skin test administration, incorrect interpretation of reactions, or incorrect bottle of antigen used (Nayak & Acharjya, 2012). Due to the test’s low specificity, most positive reactions in low-risk individuals are false positive (Starke, 1996).
Paul Farmer designed several studies that he used to help create new TB treatment methods, including a study about a system called active case finding, which helps find TB cases more quickly. The previous system of tuberculosis case finding is known as passive case finding. Passive case finding is when tu...
On December 1, 2012, a patient by the name of John Dough walks into the medical assistant’s office. The patient is five foot 11 inches tall, currently he is 70 years old and weighs approximately 211 pounds. The patient has no known allergies does not smoke and has a relatively clean health record. After filling out the patient medical history forms, the patient is seen by the doctor. The patient explains to the doctor that lately he has had trouble lifting object he would not normally have trouble with, as well as walking short distances, and being very fatigued. After further examination the patient explains how he recently found a tick on his back and removed it, but now there is a red bullseye on his back. The physician suggests a blood sample be taken and sent to the laboratory. To help with weakness and fatigue he recommends the patient to get a good nights sleep and drink plenty of fluids to avoid dehydration. He also wants the patient to limit medication intake that could contribute to fatigue such as cold and allergy medicines and make sure to finish all daily exercising three to four hours before bed. The patient schedules a check up two weeks later.
Bacterial resistance to antibiotics has presented many problems in our society, including an increased chance of fatality due to infections that could have otherwise been treated with success. Antibiotics are used to treat bacterial infections, but overexposure to these drugs give the bacteria more opportunities to mutate, forming resistant strains. Through natural selection, those few mutated bacteria are able to survive treatments of antibiotics and then pass on their genes to other bacterial cells through lateral gene transfer (Zhaxybayeva, 2011). Once resistance builds in one patient, it is possible for the strain to be transmitted to others through improper hygiene and failure to isolate patients in hospitals.
Its epidemiological importance is illustrated by World Health Organization Prevention of Tuberculosis includes better living conditions, proper nutrition, and positive health practices” (Fogel, 2015, p.530). Positive health practices include covering nose and mouth when coughing and frequent hand washing. Bacille Calmette-Gurin (BCG) vaccine tends to be given in other countries. Tuberculosis is known as one of the main causes of mortality in the world. This communicable disease is a serious public health conundrum. “The disease still puts a strain on public health, being only second to HIV/AIDS in causing high mortality rates” (Matteelli, Roggi, & Carvalho, 2014, p.
Drug resistance in mycobacterium tuberculosis (TB) has become a severe global health threat. The fight against TB is now facing major challenges due to the appearance of Multi-Drug Resistant Tuberculosis (MDR-TB) and more recently, the virtually untreatable Extensively Drug Resistant Tuberculosis (XDR-TB). MDR-TB are strains that are resistant to both top first-line drugs, Isoniazid and Rifampin, while XDR-TB are MDR-TB strains that are also resistant to any fluoroquinolone and one or more of 3 injectable drugs. With this new resistance, there emerges a great need to find new drugs that are as effective, yet bypass the problem of resistance. One method of research is to find new vulnerabilities of tuberculosis to use as new target sites of drugs. This method is highly expensive (Scheffler, Colmer, Tynan, Demain, & Gullo, 2013), and requires intense and lengthy research just to implicate the new target site. An alternative is to develop new drugs that work on the same already known target as the first-line drugs, but by a different mechanism, thereby bypassing the resistance of the TB to the drug.
The patient is a 55-year-old man admitted to the hospital for dehydration secondary to vomiting. The physical examination of the patient revealed dry mucous membranes and vital signs as follows: Pulse 110, blood pressure 100/60, and respirations of 20.
Tuberculosis is an air-borne disease, hence, it can be passed from an infected person to a healthy individual through coughing, sneezing and other salivary secretions. Tuberculosis is caused by the transfer of Mycobacteriun Tuberculosis (M. Tuberculosis) also known as Tubercle Bacillus, a small particle of 1-5 microns in diameter, due to the small size, when an infected person sneezes or coughs, about 3,000 particles are expelled. M. Tuberculosis responsible for tuberculosis is able to stay in the air for a long period of time (about 6hoursAnother way of acquiring Tuberculosis is by drinking unpasteurized milk, milk straight from cow, although this is not a common mode of transmission, it can be found in rural areas. Ingestion of contaminated cow milk transmits Mycobacterium Bovis, the animal form which is still potent enough to cause tuberculosis in humans. ). Tuberculosis transmission is affected by exposure, socioeconomic status of person, proximity, immune status of uninfected individual (%&&%&? CDC).
Hansen’s Disease also known as Leprosy dates back to at least 4000b.c. Evidence of the disease’s presents in ancient times was found on an Egyptian papyrus dating from around 1500bc. These earlier cultures believed it was a curse or punishment from the gods. During the middle ages, the afflicted wore special clothing and rang bells to alert the uninfected of their presence. The first known origin of this disease is Egypt from here Roman Crusaders contracted the disease and brought it back to Europe and from Europe to America.
is positive; three Sputum Test reveals if TB germs are in thick liquid a person
My hypothesis on Tuberculosis is that it is a very deadly disease that causes a persons lungs to fill with blood. This can harm the body by making the body suffocate itself when the lungs fill with blood.
Hepatitis B is a DNA viral infection that causes damage and inflammation to the liver. It was first discovered in 1965 by Dr. Baruch Blumberg. The HBV virus is very contagious and is even thought to be the most serious form of viral hepatitis and the most common viral infection on Earth. “HBV is 100 times more infectious than HIV.” (Green, 2002, pg. 7) The virus can survive for about one week outside the body on a dry surface. According to Green (2002, pg. 7), “One in twenty Americans has been infected with the virus at some point in their lives.” Between the ages of 15-39 is when 75% of new HBV infections occur, according to Green (2002, pg.8).
Tuberculosis is transmitted by inhalation of aerosols containing the tubercle bacilli. The required inoculum size for infection is usually high, but easily occurs with exposure to a patient who is currently infected. The products of dried aerosols, droplet nuclei, are particularly infectious because they remain in the air for an extended time, and upon inhalation easily move to the alveoli. The severe damage related to infection is caused by the reaction of the host. The tuberculosis infection has two phases, primary and secondary.
The patient has high temperature, and extreme sweating as well as visible chills on body.
Tuberculosis has plagued mankind for a long time. This disease, which was previously believed to be eradicated, has once again shown up and begun attacking the lives of many humans. Tuberculosis infects a third of the population and kills a fraction of them. Many approaches have been used including different varieties of infection control, bodily defenses, and treatments to try to protect humans from tuberculosis. The best way to prevent tuberculosis infections is to contain the source of tuberculosis. The most common source of tuberculosis infection is from infected humans. By diagnosing, containing, and treating people with latent tuberculosis before they get active, contagious tuberculosis, tuberculosis can be quickly contained. Once someone has been diagnosed with TB, they should be placed under isolation.
According to the Malaysian Medical Association (MMA), close to half of foreign workers who underwent medical tests last year are infected with the contagious airborne disease tuberculosis (TB). Local daily The Star reported today MMA president Dr H. Krishna Kumar (12 March 2015) as saying that illegal foreign workers who do not go for medical screenings are the biggest factor behind the rise in TB cases, noting that medical tests found last year that 17,981 foreign workers are infected with TB, or 47 per cent of those tested. Thus, I strongly agree that over reliance on foreign workers can cause contagious diseases to be spread in the host countries. (Dr H. Krishna Kumar,